Biology (MindTap Course List)
11th Edition
ISBN: 9781337392938
Author: Eldra Solomon, Charles Martin, Diana W. Martin, Linda R. Berg
Publisher: Cengage Learning
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Chapter 12.3, Problem 10LO
Summary Introduction
To define: Telomere and describe the possible connections between telomerase and cell aging and between telomerase and cancer.
Introduction: A telomere region has a specialized sequence of repetitive
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Describe the action of telomerase and identify the celltypes in which it continues to be synthesized.
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Chapter 12 Solutions
Biology (MindTap Course List)
Ch. 12.1 - Summarize the evidence that accumulated during the...Ch. 12.1 - Prob. 2LOCh. 12.1 - Prob. 1CCh. 12.1 - Prob. 2CCh. 12.2 - Explain how nucleotide subunits link to form a...Ch. 12.2 - Describe how the two strands of DNA are oriented...Ch. 12.2 - Prob. 5LOCh. 12.2 - Prob. 1CCh. 12.2 - Prob. 2CCh. 12.2 - Prob. 3C
Ch. 12.3 - Cite evidence from Meselson and Stahls experiment...Ch. 12.3 - Prob. 7LOCh. 12.3 - Explain the complexities of DNA replication that...Ch. 12.3 - Discuss how enzymes proofread and repair errors in...Ch. 12.3 - Prob. 10LOCh. 12.3 - How did the ability to distinguish old and newly...Ch. 12.3 - What feature of DNA structure causes DNA...Ch. 12.3 - What is the reason that eukaryotic cells require...Ch. 12 - When Griffith injected mice with a combination of...Ch. 12 - Which of the following inspired Avery and his...Ch. 12 - In the Hershey-Chase experiment with...Ch. 12 - The two complementary strands of the DNA double...Ch. 12 - If a segment of DNA is 5 CATTAC 3, the...Ch. 12 - Each DNA strand has a backbone that consists of...Ch. 12 - The experiments in which Meselson and Stahl grew...Ch. 12 - The statement DNA replicates by a semiconservative...Ch. 12 - Topoisomerases (a) synthesize DNA (b) synthesize...Ch. 12 - A lagging strand forms by (a) joining primers (b)...Ch. 12 - The immediate source of energy for DNA replication...Ch. 12 - Which of the following statements about eukaryotic...Ch. 12 - Prob. 13TYUCh. 12 - Prob. 14TYUCh. 12 - Prob. 15TYUCh. 12 - INTERPRET DATA In the Hershey-Chase experiment,...Ch. 12 - EVOLUTION LINK How does DNA being the universal...
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- A). Briefly describe the function of telomerase. B). How does the structure of telomerase allow it to complete the function you described?arrow_forwardIn your own words, explain how cancer cells differ from normal cells in regard to the following: Telomeres, which are products of telomerase enzymearrow_forwarddescribe the telomere shortening problem and how it is solved by telomerase?arrow_forward
- Discuss the levels of chromosomal organization with reference to the following terms: a. nucleotide b. DNA double helix c. histones d. nucleosomes e. chromatinarrow_forwardWhich of the following statements are correct about telomeres (select all that apply)? A. A total of 6 nucleotides are lost at the end of each chromsome during each replication cycle. B. Addition of telomerase to cells that have undergone breakage-fusion-bridge cycles can reverse crisis C. Shortening of telomeres prevents cells from becoming cancerous even if they have oncogenes and defective tumor suppressor genes D. All cancer cells express high levels of telomerase E. Chromosomes without telomeres tend to undergo end-to-end fusionsarrow_forwardHow might our knowledge about telomeres and telomerase be applied to anti-aging strategies? Are such strategies or therapies developed?arrow_forward
- Question -Search for a change in telomerase activity related to aging or a disease. Describe how the length of telomeres is changed. How does the change in telomerase activity relate to a symptom of the disorder or aging.arrow_forwardwhat telomerase does and why it's necessary?arrow_forwardIf telomeres are normally shortened after each round of replication in somatic cells (see Chapter 12), what prediction would you make about the length of telomeres in Dolly, the first cloned sheeparrow_forward
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