EBK LIFE: THE SCIENCE OF BIOLOGY
11th Edition
ISBN: 8220103935432
Author: Sadava
Publisher: MAC HIGHER
expand_more
expand_more
format_list_bulleted
Concept explainers
Question
Chapter 13.3, Problem 4R
Summary Introduction
To review:
The dideoxycytidine drug and its interaction with the DNA molecule.
Introduction:
DNA is deoxyribonucleic acid and it is known to be a genetic material for all the organisms, expect viruses. Dideoxycytidine is a drug which is widely used to treat the viral infections. This drug interacts with the DNA and inhibits the synthesis of the DNA and hence it stops the growth of the virus.
Expert Solution & Answer
Want to see the full answer?
Check out a sample textbook solutionStudents have asked these similar questions
DNA in the form of a double helix must be associated with cations, usually Mg²+ . Why is this requirement the case?
Why do think nucleotides are also sometimes referred to as “bases” or “nucleotide bases”?
What is the difference between a nucleotide and a nucleoside? Explain by giving an example, using structures.
What kind of bond links a base to some sugar? Is the sugar an alpha or beta anomer? In what position(s) of the sugar does this occur? In what position(s) of the base does this occur?
Instead of the term “Formation of a nucleoside”, what could the name of the reaction be? What functional group is being formed?
Define the primary structure of DNA/RNA. Compare and contrast to the primary structure of proteins.
Draw the RNA dinucleotide formed if deoxyguanidine 5'phosphate and deoxythymidine 5'phosphate monophosphates
undergo a condensation reaction.
Label the 5' and 3' ends of your structure.
0-P-O-CH2
NH2
--P-O-CH2
Identify the phosphodiester bond.
\H
KH
H.
H
H
H
H
ОН
H
ОН
H
G
Chapter 13 Solutions
EBK LIFE: THE SCIENCE OF BIOLOGY
Knowledge Booster
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.Similar questions
- Match the following nucleobases (designated AD) with their names and answer questions about them. NH, NH, C D NH2 Note that some of the items from the answer list should NOT be used. Guanine 1. Aand B - Cytosine 2 Cand D • Adenine 3. Not shuwn v Thymine 4. D v Uracil 5. B a Aand C v Which of tho shown bases are pyrimidines? 7. A and O v Which of the shown bases form canonical A-T Watson-Crick base pair? S. A v Which of the shown bases form canonical G-C Watson.Crick base-pair? 9. Band C 10. C 11. Band Darrow_forward5-Bromouridine is known to induce mutations in DNA. One of the characteristics of this compound is that the enol form is favored relative to the keto form. Draw the keto- and the eno- tautomers of the base. Determine (and draw) which base (A, T, G, or C) would most likely interact with each of the two forms by base-pair.arrow_forwardIn pyrimidine nucleosides the anti conformation predominates because of steric interactions with pentose. Do thepurine nucleosides have similar interactions?arrow_forward
- The disaccharide α,β-trehalose differs from the α, α structure as shown by having an (α1→ β1) linkage. Draw its structure as a Haworth projection.arrow_forwardWhich of the following nucleotides found in DNA is dGTP? Note, hydrogens bound to carbon atoms are not shown.arrow_forwardName the following nucleotide: HN -0-P -0-CH2 OHarrow_forward
- The structure below shows that of a trisaccharide that is composed of (going from top left to bottom right) galactose, glucose, and fructose. The galactose residue is linked to glucose via a/an [alpha linkage, beta linkage] and the glucose residue is linked to fructose via a/an [alpha linkage, beta linkage].arrow_forwardA nucleoside consists of an organic base, bound to ribose or deoxyribose. Draw the structure for deoxyguanosine, formed from guanine and deoxyribose.arrow_forwardSnake venom phosphodiesterase hydrolyzes nucleotides from the 3' end of any oligonucleotide and cleaves between the 3' hydroxyl of the ribose or deoxyribose and the phosphoryl group of the next nucleotide. It acts on single-stranded DNA or RNA and has no base specificity. Which nucleotide would be released first from the oligonucleotide shown below upon treatment with snake venom phosphodiesterase? choices a. Deoxythymidine 5'-monophosphate b. Deoxyguanosine 3'-monophosphate c. Deoxyguanosine 5'-monophosphate d. Guanosine 5'-monophosphate e. Deoxythymidinearrow_forward
- The alkaline hydrolysis of pAUGCAGC oligonucleotide produces: O A. Uridine 2'-monophosphate, uridine 3'-monophosphate, cytosine 2'-monophosphate O B. Adenosine 2'-monophosphate, adenosine 3'-monophosphate, adenosine 21,5'-bisphosphate OC. Guanosine 2'-monophosphate, guanosine 3'-monophosphate, cytosine 3'-monophosphate O D. Cytidine 3'-monophosphate, guanosine 2'-monophosphate, adenine 2'-monophosphate O E. Adenine 3,5'-bisphosphate, guanine 2,5'-bisphosphate, uridine 2'-monophosphate O F. Uridine 2'-monophosphate, uridine 3'-monophosphate, guanine 3'-monophosphatearrow_forwardDraw the structure of the following nucleotide: adenosine 3'-monophosphate or guanosine 2-monophosphatearrow_forwardIdentify if the following is a pyrimidine/purine nucleotide or a pyrimidine/purine nucleoside and write whether the sugar moiety is a ribose or deoxyribose. NH2 NH2 HO-P-o HO В. ÓH ÓH ОН H3C. NH HN но С. OCH2 CH2 D. H. OH он OHarrow_forward
arrow_back_ios
SEE MORE QUESTIONS
arrow_forward_ios
Recommended textbooks for you
- Human Anatomy & Physiology (11th Edition)BiologyISBN:9780134580999Author:Elaine N. Marieb, Katja N. HoehnPublisher:PEARSONBiology 2eBiologyISBN:9781947172517Author:Matthew Douglas, Jung Choi, Mary Ann ClarkPublisher:OpenStaxAnatomy & PhysiologyBiologyISBN:9781259398629Author:McKinley, Michael P., O'loughlin, Valerie Dean, Bidle, Theresa StouterPublisher:Mcgraw Hill Education,
- Molecular Biology of the Cell (Sixth Edition)BiologyISBN:9780815344322Author:Bruce Alberts, Alexander D. Johnson, Julian Lewis, David Morgan, Martin Raff, Keith Roberts, Peter WalterPublisher:W. W. Norton & CompanyLaboratory Manual For Human Anatomy & PhysiologyBiologyISBN:9781260159363Author:Martin, Terry R., Prentice-craver, CynthiaPublisher:McGraw-Hill Publishing Co.Inquiry Into Life (16th Edition)BiologyISBN:9781260231700Author:Sylvia S. Mader, Michael WindelspechtPublisher:McGraw Hill Education
Human Anatomy & Physiology (11th Edition)
Biology
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:PEARSON
Biology 2e
Biology
ISBN:9781947172517
Author:Matthew Douglas, Jung Choi, Mary Ann Clark
Publisher:OpenStax
Anatomy & Physiology
Biology
ISBN:9781259398629
Author:McKinley, Michael P., O'loughlin, Valerie Dean, Bidle, Theresa Stouter
Publisher:Mcgraw Hill Education,
Molecular Biology of the Cell (Sixth Edition)
Biology
ISBN:9780815344322
Author:Bruce Alberts, Alexander D. Johnson, Julian Lewis, David Morgan, Martin Raff, Keith Roberts, Peter Walter
Publisher:W. W. Norton & Company
Laboratory Manual For Human Anatomy & Physiology
Biology
ISBN:9781260159363
Author:Martin, Terry R., Prentice-craver, Cynthia
Publisher:McGraw-Hill Publishing Co.
Inquiry Into Life (16th Edition)
Biology
ISBN:9781260231700
Author:Sylvia S. Mader, Michael Windelspecht
Publisher:McGraw Hill Education
DNA vs RNA (Updated); Author: Amoeba Sisters;https://www.youtube.com/watch?v=JQByjprj_mA;License: Standard youtube license