Principles of Biology
2nd Edition
ISBN: 9781259875120
Author: Robert Brooker, Eric P. Widmaier Dr., Linda Graham Dr. Ph.D., Peter Stiling Dr. Ph.D.
Publisher: McGraw-Hill Education
expand_more
expand_more
format_list_bulleted
Concept explainers
Question
Chapter 13.4, Problem 4CC
Summary Introduction
To analyze:
If cell can become cancerous or not, in case both the copies of Rb gene and E2F gene are inactivated.
Introduction:
The cancer cells can be characterized as the cells that that divide in an uncontrolled manner, which can form solid tumors and invade other tissues. They are result of mutation in the genes that promote the uncontrolled division.
Expert Solution & Answer
Want to see the full answer?
Check out a sample textbook solutionStudents have asked these similar questions
why EGFR play a role in CRC and other cancer?
Explain why p53 is mutated in the vast majority of human cancers.
Why does a single mutation in a proto-oncogene, turning it into an oncogene potentially lead to a cancerous phenotype, while it takes two mutations in tumor suppressor genes to lead to a cancerous phenotype?
Chapter 13 Solutions
Principles of Biology
Ch. 13.1 - Prob. 1CCCh. 13.1 - Prob. 2CCCh. 13.1 - Prob. 1TYKCh. 13.1 - Prob. 2TYKCh. 13.2 - Prob. 1CCCh. 13.2 - Prob. 2CCCh. 13.2 - Prob. 1TYKCh. 13.2 - Prob. 2TYKCh. 13.3 - Prob. 1CCCh. 13.3 - Prob. 1TYK
Ch. 13.4 - Prob. 1CCCh. 13.4 - Prob. 1BCCh. 13.4 - Prob. 2CCCh. 13.4 - Prob. 3CCCh. 13.4 - Prob. 4CCCh. 13.4 - Prob. 1TYKCh. 13.4 - Prob. 2TYKCh. 13 - A mutation removes a single base pair within the...Ch. 13 - Prob. 2TYCh. 13 - Prob. 3TYCh. 13 - Prob. 4TYCh. 13 - Prob. 5TYCh. 13 - Prob. 6TYCh. 13 - Prob. 7TYCh. 13 - Prob. 8TYCh. 13 - Prob. 9TYCh. 13 - Prob. 10TYCh. 13 - Prob. 1CCQCh. 13 - Prob. 2CCQCh. 13 - Prob. 3CCQCh. 13 - Prob. 1CBQCh. 13 - Prob. 2CBQ
Knowledge Booster
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.Similar questions
- Can you think of two ways in which the function of p53 can be disrupted?arrow_forwardAccording to the multi-hit model, more than one mutation must occur in a cell for cancer to develop. Once an oncogene has been formed by a mutation, what other type of gene must also mutate?arrow_forwardExplain the molecular mechanisms of cancers caused by a P53 gene mutation.arrow_forward
- How do oncogenes differ from tumor suppressor genes?arrow_forwardHow can the role of epigenetics in cancer be reconciled with the idea that cancer is caused by the accumulation of genetic mutations in tumor-suppressor genes and proto-oncogenes?arrow_forwardwhat are the rolls that the p53 gene and RAS protein take on when trying to stop a cancer cell from further replicating. Also, what would happen if a mutation were to occur in both genes?arrow_forward
- Do you think there are more unique alleles of p53 that lead to cancer or more unique alleles of Ras that lead to cancer? Please explain.arrow_forwardSome cancers are consistently associated with the deletion of a particularpart of a chromosome. Does the deleted region contain an oncogene or atumor-suppressor gene? Explain.arrow_forwardDescribe how mutations in genome maintenance factors promote tumorigenesis. Why would inactivation of a mis- match repair gene cause colon cancer?arrow_forward
- How do normal cells protect themselves from accumulating mutations in genes that could lead to cancer? How do cancer cells differ from normal cells in these processes?arrow_forwardWhat are Two kinds of cancer-producing mutations?arrow_forwardDefine oncogene, proto-oncogene, and tumor-suppressor gene.arrow_forward
arrow_back_ios
SEE MORE QUESTIONS
arrow_forward_ios
Recommended textbooks for you
- Human Anatomy & Physiology (11th Edition)BiologyISBN:9780134580999Author:Elaine N. Marieb, Katja N. HoehnPublisher:PEARSONBiology 2eBiologyISBN:9781947172517Author:Matthew Douglas, Jung Choi, Mary Ann ClarkPublisher:OpenStaxAnatomy & PhysiologyBiologyISBN:9781259398629Author:McKinley, Michael P., O'loughlin, Valerie Dean, Bidle, Theresa StouterPublisher:Mcgraw Hill Education,
- Molecular Biology of the Cell (Sixth Edition)BiologyISBN:9780815344322Author:Bruce Alberts, Alexander D. Johnson, Julian Lewis, David Morgan, Martin Raff, Keith Roberts, Peter WalterPublisher:W. W. Norton & CompanyLaboratory Manual For Human Anatomy & PhysiologyBiologyISBN:9781260159363Author:Martin, Terry R., Prentice-craver, CynthiaPublisher:McGraw-Hill Publishing Co.Inquiry Into Life (16th Edition)BiologyISBN:9781260231700Author:Sylvia S. Mader, Michael WindelspechtPublisher:McGraw Hill Education
Human Anatomy & Physiology (11th Edition)
Biology
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:PEARSON
Biology 2e
Biology
ISBN:9781947172517
Author:Matthew Douglas, Jung Choi, Mary Ann Clark
Publisher:OpenStax
Anatomy & Physiology
Biology
ISBN:9781259398629
Author:McKinley, Michael P., O'loughlin, Valerie Dean, Bidle, Theresa Stouter
Publisher:Mcgraw Hill Education,
Molecular Biology of the Cell (Sixth Edition)
Biology
ISBN:9780815344322
Author:Bruce Alberts, Alexander D. Johnson, Julian Lewis, David Morgan, Martin Raff, Keith Roberts, Peter Walter
Publisher:W. W. Norton & Company
Laboratory Manual For Human Anatomy & Physiology
Biology
ISBN:9781260159363
Author:Martin, Terry R., Prentice-craver, Cynthia
Publisher:McGraw-Hill Publishing Co.
Inquiry Into Life (16th Edition)
Biology
ISBN:9781260231700
Author:Sylvia S. Mader, Michael Windelspecht
Publisher:McGraw Hill Education
An Introduction to the Human Genome | HMX Genetics; Author: Harvard University;https://www.youtube.com/watch?v=jEJp7B6u_dY;License: Standard Youtube License