Essentials of Genetics, Books a la Carte Plus Mastering Genetics with eText -- Access Card Package (9th Edition)
9th Edition
ISBN: 9780134319070
Author: William S. Klug, Michael R. Cummings, Charlotte A. Spencer, Michael A. Palladino
Publisher: PEARSON
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Textbook Question
Chapter 14, Problem 10PDQ
Why are frameshift mutations likely to be more detrimental than point mutations, in which a single pyrimidine or purine has been substituted?
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Why are frameshift mutations likely to be more detrimental than point mutations, in which a single pyrimidine or purine has been substituted?
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Chapter 14 Solutions
Essentials of Genetics, Books a la Carte Plus Mastering Genetics with eText -- Access Card Package (9th Edition)
Ch. 14 - CASE STUDY| Genetic dwarfism Seven months...Ch. 14 -
CASE STUDY | Genetic dwarfism
Seven months...Ch. 14 -
CASE STUDY| Genetic dwarfism
Seven months...Ch. 14 - CASE STUDY | Genetic dwarfism Seven months...Ch. 14 -
HOW DO WE KNOW?
1. In this chapter, we focused on...Ch. 14 - Review the Chapter Concepts list on page 257....Ch. 14 - What is a spontaneous mutation, and why are...Ch. 14 -
4. Why would a mutation in a somatic cell of a...Ch. 14 - Why is a random mutation more likely to be...Ch. 14 - Most mutations in a diploid organism are...
Ch. 14 - What is meant by a conditional mutation?Ch. 14 -
8. Describe a tautomeric shift and how it may...Ch. 14 - Contrast and compare the mutagenic effects of...Ch. 14 - Why are frameshift mutations likely to be more...Ch. 14 - Why are X rays more potent mutagens than UV...Ch. 14 -
12. DNA damage brought on by a variety of natural...Ch. 14 - Contrast the various types of DNA repair...Ch. 14 -
14. Mammography is an accurate screening...Ch. 14 - Describe how the Ames test screens for potential...Ch. 14 - What genetic defects result in the disorder...Ch. 14 - In a bacterial culture in which all cells are...Ch. 14 - Human equivalents of bacterial DNA mismatch repair...Ch. 14 - A number of different types of mutations in the...Ch. 14 -
20. Some mutations that lead to diseases such as...Ch. 14 - In maize, a Ds or Ac transposon can cause...Ch. 14 -
22. Presented here are hypothetical findings from...Ch. 14 -
23. Cystic fibrosis (CF) is a severe autosomal...Ch. 14 -
24. Electrophilic oxidants are known to create...Ch. 14 - Skin cancer carries a lifetime risk nearly equal...Ch. 14 -
26. The initial discovery of IS elements in...Ch. 14 -
27. It is estimated that about 0.2 percent of...Ch. 14 -
28. It has been noted that most transposons in...Ch. 14 - Two related forms of muscular dystrophy–Duchenne...
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Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.Similar questions
- What is the likely consequence of a frameshift mutation?arrow_forwardWhat type of mutation is shown in the diagram?  Why do you think this type of mutation is referred to by this term?arrow_forwardExplain why STR mutations are found at a much higher frequency than single nucleotide changes?arrow_forward
- What is a transposon? Explain why the insertion of a transposon into the DNA of a cell can lead to a mutationarrow_forwardWhat three different types of mutations involve changes in a single base, and what effect can each of them have on a coding sequence? Which type is the most common? Which type has the most severe effect on the function of the encoded protein?arrow_forwardWhich of the above mutations will result in a shift in the reading frame?arrow_forward
- What type of mutation (missense, silent, and non-sense) was introduced in your sequence when G was substituted with C?arrow_forward. Can a missense mutation of proline to histidine bemade with a G • C → A • T transition-causing mutagen?What about a proline-to-serine missense mutation?arrow_forwardHow does the effect of nonsense mutation differ from that of a frameshift mutation? Why?arrow_forward
- A mutant strain of bacteria is isolated in which the amino acid glutamine is often erroneously substituted for glutamic acid during protein synthesis. What kind of mutation might be underlying this defect? How could you test this hypothesis?arrow_forwardWhat is the purpose of the random hexamer primers? Why can’t a researcher use a poly-T primer in a reverse transcriptase reaction that utilizes prokaryotic mRNA as a template?arrow_forwardWhat type DNA mutation is TACAT?arrow_forward
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