The antibiotic, nigericin or valinomycin, which would have the greater effect on oxidative phosphorylation when administered to respiring mitochondria, needs to be predicted by assuming that antibiotics are added to a suspension of mitochondria in equimolar amounts. Briefly explain your reasoning. Introduction: Proton motive force (pmf) is the energy inherent in the difference in proton concentration across the mitochondria membrane. PMF has two components: The chemical potential energy due to the difference in the H+ concentration across the membrane. The electrical potential energy when a proton crosses the membrane without a counter ion. The electrochemical gradient generated by the ion pump is: ΔG = ( 5 .70kJ/mol ) ΔpH + 96 .5 kJ/V . mol) ΔΨ . . . . ( equation 1 )

Question

Want to see the full answer?

Answer 1

Question

Chapter 14, Problem 20P

Interpretation Introduction

Interpretation:

The antibiotic, nigericin or valinomycin, which would have the greater effect on oxidative phosphorylation when administered to respiring mitochondria, needs to be predicted by assuming that antibiotics are added to a suspension of mitochondria in equimolar amounts. Briefly explain your reasoning.

Introduction:

Proton motive force (pmf) is the energy inherent in the difference in proton concentration across the mitochondria membrane. PMF has two components:

The chemical potential energy due to the difference in the H+ concentration across the membrane.

The electrical potential energy when a proton crosses the membrane without a counter ion.
The electrochemical gradient generated by the ion pump is:
ΔG = (5.70kJ/mol) ΔpH + 96.5 kJ/V. mol) ΔΨ . . . . (equation 1)

Expert Solution & Answer

Want to see the full answer?

Check out a sample textbook solution

See solution

Answer 2

Question

Chapter 14, Problem 20P

Interpretation Introduction

Interpretation:

The antibiotic, nigericin or valinomycin, which would have the greater effect on oxidative phosphorylation when administered to respiring mitochondria, needs to be predicted by assuming that antibiotics are added to a suspension of mitochondria in equimolar amounts. Briefly explain your reasoning.

Introduction:

Proton motive force (pmf) is the energy inherent in the difference in proton concentration across the mitochondria membrane. PMF has two components:

The chemical potential energy due to the difference in the H+ concentration across the membrane.

The electrical potential energy when a proton crosses the membrane without a counter ion.
The electrochemical gradient generated by the ion pump is:
ΔG = (5.70kJ/mol) ΔpH + 96.5 kJ/V. mol) ΔΨ . . . . (equation 1)

Expert Solution & Answer

Want to see the full answer?

Check out a sample textbook solution

See solution

Answer 3

Question

Chapter 14, Problem 20P

Interpretation Introduction

Interpretation:

The antibiotic, nigericin or valinomycin, which would have the greater effect on oxidative phosphorylation when administered to respiring mitochondria, needs to be predicted by assuming that antibiotics are added to a suspension of mitochondria in equimolar amounts. Briefly explain your reasoning.

Introduction:

Proton motive force (pmf) is the energy inherent in the difference in proton concentration across the mitochondria membrane. PMF has two components:

The chemical potential energy due to the difference in the H+ concentration across the membrane.

The electrical potential energy when a proton crosses the membrane without a counter ion.
The electrochemical gradient generated by the ion pump is:
ΔG = (5.70kJ/mol) ΔpH + 96.5 kJ/V. mol) ΔΨ . . . . (equation 1)

Expert Solution & Answer

Want to see the full answer?

Check out a sample textbook solution

See solution

Answer 4

Question

Chapter 14, Problem 20P

Interpretation Introduction

Interpretation:

The antibiotic, nigericin or valinomycin, which would have the greater effect on oxidative phosphorylation when administered to respiring mitochondria, needs to be predicted by assuming that antibiotics are added to a suspension of mitochondria in equimolar amounts. Briefly explain your reasoning.

Introduction:

Proton motive force (pmf) is the energy inherent in the difference in proton concentration across the mitochondria membrane. PMF has two components:

The chemical potential energy due to the difference in the H+ concentration across the membrane.

The electrical potential energy when a proton crosses the membrane without a counter ion.
The electrochemical gradient generated by the ion pump is:
ΔG = (5.70kJ/mol) ΔpH + 96.5 kJ/V. mol) ΔΨ . . . . (equation 1)

Expert Solution & Answer

Want to see the full answer?

Check out a sample textbook solution

See solution

Answer 5

Chapter 14, Problem 20P

Interpretation Introduction

Interpretation:

The antibiotic, nigericin or valinomycin, which would have the greater effect on oxidative phosphorylation when administered to respiring mitochondria, needs to be predicted by assuming that antibiotics are added to a suspension of mitochondria in equimolar amounts. Briefly explain your reasoning.

Introduction:

Proton motive force (pmf) is the energy inherent in the difference in proton concentration across the mitochondria membrane. PMF has two components:

The chemical potential energy due to the difference in the H+ concentration across the membrane.

The electrical potential energy when a proton crosses the membrane without a counter ion.
The electrochemical gradient generated by the ion pump is:
ΔG = (5.70kJ/mol) ΔpH + 96.5 kJ/V. mol) ΔΨ . . . . (equation 1)

Answer 6

Chapter 14, Problem 20P

Interpretation Introduction

Interpretation:

The antibiotic, nigericin or valinomycin, which would have the greater effect on oxidative phosphorylation when administered to respiring mitochondria, needs to be predicted by assuming that antibiotics are added to a suspension of mitochondria in equimolar amounts. Briefly explain your reasoning.

Introduction:

Proton motive force (pmf) is the energy inherent in the difference in proton concentration across the mitochondria membrane. PMF has two components:

The chemical potential energy due to the difference in the H+ concentration across the membrane.

The electrical potential energy when a proton crosses the membrane without a counter ion.
The electrochemical gradient generated by the ion pump is:
ΔG = (5.70kJ/mol) ΔpH + 96.5 kJ/V. mol) ΔΨ . . . . (equation 1)

Answer 7

Chapter 14, Problem 20P

Interpretation Introduction

Interpretation:

The antibiotic, nigericin or valinomycin, which would have the greater effect on oxidative phosphorylation when administered to respiring mitochondria, needs to be predicted by assuming that antibiotics are added to a suspension of mitochondria in equimolar amounts. Briefly explain your reasoning.

Introduction:

Proton motive force (pmf) is the energy inherent in the difference in proton concentration across the mitochondria membrane. PMF has two components:

The chemical potential energy due to the difference in the H+ concentration across the membrane.

The electrical potential energy when a proton crosses the membrane without a counter ion.
The electrochemical gradient generated by the ion pump is:
ΔG = (5.70kJ/mol) ΔpH + 96.5 kJ/V. mol) ΔΨ . . . . (equation 1)

Answer 8

Expert Solution & Answer

Answer 9

Expert Solution & Answer

Answer 10

Want to see the full answer?

Check out a sample textbook solution

See solution

Answer 11

Ch. 14 - Prob. 1P Ch. 14 - When pure reduced cytochrome c is added to...Ch. 14 - Freshly prepared mitochondria were incubated with...Ch. 14 - Prob. 4P Ch. 14 - Prob. 5P Ch. 14 - Prob. 6P Ch. 14 - Intramitochondrial ATP concentrations are about 5...Ch. 14 - Prob. 8P Ch. 14 - Prob. 9P Ch. 14 - Years ago there was interest in using uncouplers...

Concept explainers

Videos

Want to see the full answer?

Chapter 14 Solutions