On adding GTPgammas which is a non-hydrolysable analog of GTP, the increase in the duration of hormone response needs to be explained. Concept introduction: GTPgammas is a non-hydrolysable or slowly hydrolysable G-protein which is an activating equivalent of guanosine triphosphate(GTP). These get bound to GTP and are inactivated through phosphodiester bond hydrolysis.

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Chapter 14, Problem 7P

Interpretation Introduction

Interpretation:

On adding GTPgammas which is a non-hydrolysable analog of GTP, the increase in the duration of hormone response needs to be explained.

Concept introduction:

GTPgammas is a non-hydrolysable or slowly hydrolysable G-protein which is an activating equivalent of guanosine triphosphate(GTP). These get bound to GTP and are inactivated through phosphodiester bond hydrolysis.

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