The reason why most cell surface receptors use long, indirect signaling cascades to start transcription in the nucleus instead of notch cell surface receptors, which can rapidly activate transcription in short steps. Concept introduction: Notch-Delta system of receptors has direct and rapid amplification steps to reach the nucleus and begin gene transcription. The receptor is activated when the ligand binds to the extracellular site of the receptor. A part of Delta receptor gets cleaved on the intracellular side and it is diffuses along the cytosol from the plasma membrane and reaches the nucleus to initiate transcription by activating transcription factors.

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Answer 1

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Chapter 16, Problem 10Q

Summary Introduction

To explain: The reason why most cell surface receptors use long, indirect signaling cascades to start transcription in the nucleus instead of notch cell surface receptors, which can rapidly activate transcription in short steps.

Concept introduction: Notch-Delta system of receptors has direct and rapid amplification steps to reach the nucleus and begin gene transcription. The receptor is activated when the ligand binds to the extracellular site of the receptor. A part of Delta receptor gets cleaved on the intracellular side and it is diffuses along the cytosol from the plasma membrane and reaches the nucleus to initiate transcription by activating transcription factors.

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Answer 2

Question

Chapter 16, Problem 10Q

Summary Introduction

To explain: The reason why most cell surface receptors use long, indirect signaling cascades to start transcription in the nucleus instead of notch cell surface receptors, which can rapidly activate transcription in short steps.

Concept introduction: Notch-Delta system of receptors has direct and rapid amplification steps to reach the nucleus and begin gene transcription. The receptor is activated when the ligand binds to the extracellular site of the receptor. A part of Delta receptor gets cleaved on the intracellular side and it is diffuses along the cytosol from the plasma membrane and reaches the nucleus to initiate transcription by activating transcription factors.

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Answer 3

Question

Chapter 16, Problem 10Q

Summary Introduction

To explain: The reason why most cell surface receptors use long, indirect signaling cascades to start transcription in the nucleus instead of notch cell surface receptors, which can rapidly activate transcription in short steps.

Concept introduction: Notch-Delta system of receptors has direct and rapid amplification steps to reach the nucleus and begin gene transcription. The receptor is activated when the ligand binds to the extracellular site of the receptor. A part of Delta receptor gets cleaved on the intracellular side and it is diffuses along the cytosol from the plasma membrane and reaches the nucleus to initiate transcription by activating transcription factors.

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Answer 4

Question

Chapter 16, Problem 10Q

Summary Introduction

To explain: The reason why most cell surface receptors use long, indirect signaling cascades to start transcription in the nucleus instead of notch cell surface receptors, which can rapidly activate transcription in short steps.

Concept introduction: Notch-Delta system of receptors has direct and rapid amplification steps to reach the nucleus and begin gene transcription. The receptor is activated when the ligand binds to the extracellular site of the receptor. A part of Delta receptor gets cleaved on the intracellular side and it is diffuses along the cytosol from the plasma membrane and reaches the nucleus to initiate transcription by activating transcription factors.

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Answer 5

Chapter 16, Problem 10Q

Summary Introduction

To explain: The reason why most cell surface receptors use long, indirect signaling cascades to start transcription in the nucleus instead of notch cell surface receptors, which can rapidly activate transcription in short steps.

Concept introduction: Notch-Delta system of receptors has direct and rapid amplification steps to reach the nucleus and begin gene transcription. The receptor is activated when the ligand binds to the extracellular site of the receptor. A part of Delta receptor gets cleaved on the intracellular side and it is diffuses along the cytosol from the plasma membrane and reaches the nucleus to initiate transcription by activating transcription factors.

Answer 6

Chapter 16, Problem 10Q

Summary Introduction

To explain: The reason why most cell surface receptors use long, indirect signaling cascades to start transcription in the nucleus instead of notch cell surface receptors, which can rapidly activate transcription in short steps.

Concept introduction: Notch-Delta system of receptors has direct and rapid amplification steps to reach the nucleus and begin gene transcription. The receptor is activated when the ligand binds to the extracellular site of the receptor. A part of Delta receptor gets cleaved on the intracellular side and it is diffuses along the cytosol from the plasma membrane and reaches the nucleus to initiate transcription by activating transcription factors.

Answer 7

Chapter 16, Problem 10Q

Summary Introduction

To explain: The reason why most cell surface receptors use long, indirect signaling cascades to start transcription in the nucleus instead of notch cell surface receptors, which can rapidly activate transcription in short steps.

Concept introduction: Notch-Delta system of receptors has direct and rapid amplification steps to reach the nucleus and begin gene transcription. The receptor is activated when the ligand binds to the extracellular site of the receptor. A part of Delta receptor gets cleaved on the intracellular side and it is diffuses along the cytosol from the plasma membrane and reaches the nucleus to initiate transcription by activating transcription factors.

Answer 8

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Answer 11

Ch. 16 - Prob. 1Q Ch. 16 - Prob. 2Q Ch. 16 - Prob. 3Q Ch. 16 - Prob. 4Q Ch. 16 - Prob. 5Q Ch. 16 - Prob. 6Q Ch. 16 - Prob. 7Q Ch. 16 - Prob. 8Q Ch. 16 - Prob. 9Q Ch. 16 - Prob. 10Q

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