To explain: The consequences of ryanodine calcium channels present in the sarcoplasmic reticulum. Unlike IP3 opened channels, these are opened by the binding of calcium itself.
Concept introduction: Sarcoplasmic reticulum is a special type of endoplasmic reticulum found in the muscle cells. They have more number of calcium channels than normal. PL C cleaves the phosphatidyl inositol to generate secondary messengers: inositol triphosphate (IP3) and diacylglycerol (DAG). IP3 then opens the Ca2+ ion channels present on the membrane of the endoplasmic reticulum (ER).The above is the case of normal ER. In the case of muscle cells where troponin is present, there is a requirement of higher amount of Ca2+ ions, as it has high affinity for it and large number of calcium ions are required for muscle contraction signaling. So, a special type of calcium channel called ryanodine channel is present. Ryanodine channel is opened by the presence of calcium ions itself.
Want to see the full answer?
Check out a sample textbook solution- Human Anatomy & Physiology (11th Edition)BiologyISBN:9780134580999Author:Elaine N. Marieb, Katja N. HoehnPublisher:PEARSONBiology 2eBiologyISBN:9781947172517Author:Matthew Douglas, Jung Choi, Mary Ann ClarkPublisher:OpenStaxAnatomy & PhysiologyBiologyISBN:9781259398629Author:McKinley, Michael P., O'loughlin, Valerie Dean, Bidle, Theresa StouterPublisher:Mcgraw Hill Education,
- Molecular Biology of the Cell (Sixth Edition)BiologyISBN:9780815344322Author:Bruce Alberts, Alexander D. Johnson, Julian Lewis, David Morgan, Martin Raff, Keith Roberts, Peter WalterPublisher:W. W. Norton & CompanyLaboratory Manual For Human Anatomy & PhysiologyBiologyISBN:9781260159363Author:Martin, Terry R., Prentice-craver, CynthiaPublisher:McGraw-Hill Publishing Co.Inquiry Into Life (16th Edition)BiologyISBN:9781260231700Author:Sylvia S. Mader, Michael WindelspechtPublisher:McGraw Hill Education