(a)
To explain: How deficiency of insulin receptor affects the levels of circulating glucose instantly after a meal.
Concept introduction: The insulin is a natural occurring hormone that is secreted from the pancreas in response to high level of circulating glucose. The hormonal stimulation by insulin enhances the rate of glucose transport into several types of cells those have both insulin receptors and insulin-sensitive glucose transporters on the surface of the cell.
(b)
To explain: How deficiency of insulin receptor affects the rate of glycogen synthesis in muscle.
Concept introduction: The insulin is a natural occurring hormone that is secreted from the pancreas in response to high level of circulating glucose. The hormonal stimulation by insulin enhances the rate of glucose transport into several types of cells those have both insulin receptors and insulin-sensitive glucose transporters on the surface of the cell.
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