a)
Interpretation:
The flaw in the synthesis given is to be stated.
Concept introduction:
In aromatic electrophilic substitution reactions, alkyl groups are ortho and para directing and activating groups while carboxylic acid group are meta directing and deactivating group. While oxidizing with KMnO4 the alkyl groups in the side chain are oxidized and the aromatic ring remains unaffected.
To state:
The flaw in the synthesis given.
b)
Interpretation:
The flaw in the synthesis given is to be stated.
Concept introduction:
In aromatic electrophilic substitution reactions, halogens are ortho and para directing groups. Friedal-Crafts alkylation is not possible with
To state:
The flaw in the synthesis given.
c)
Interpretation:
The flaw in the synthesis given is to be stated.
Concept introduction:
In aromatic electrophilic substitution reactions, alkyl groups are ortho and para directing and activating groups while carbonyl group is a meta directing and deactivating group. When treated with H2/Pd the –C=O group gets reduced to –CH2 group and –NO2 gets reduced to –NH2 group.
To state:
The flaw in the synthesis shown.
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Chapter 16 Solutions
Bundle: Organic Chemistry, Loose-leaf Version, 9th + LMS Integrated for OWLv2, 4 terms (24 months) Printed Access Card
- Please devise syntheses of the product compounds below from their respective starting materials. Each of the synthesis will require multiple steps.arrow_forwardProvide a structure for the major products of the reactions and include the steps for each reaction.arrow_forward3 Propose a synthesis for the compounds below from benzene.arrow_forward
- Propose a synthesis for the following molecules, starting from benzene or a named variant.arrow_forwardComplete the following syntheses by filling in the missing structures or reagents! Thank you!arrow_forwardProvide the correct conditions and their major products for the two reactions below:arrow_forward
- Organic Chemistry: A Guided InquiryChemistryISBN:9780618974122Author:Andrei StraumanisPublisher:Cengage LearningOrganic ChemistryChemistryISBN:9781305580350Author:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. FootePublisher:Cengage Learning