Biological Science (7th Edition)
7th Edition
ISBN: 9780134678320
Author: Scott Freeman, Kim Quillin, Lizabeth Allison, Michael Black, Greg Podgorski, Emily Taylor, Jeff Carmichael
Publisher: PEARSON
expand_more
expand_more
format_list_bulleted
Concept explainers
Textbook Question
Chapter 17, Problem 11PIAT
What better not be for dinner?
Eating even a single death cap mushroom (Amanita phalloides) can be fatal due to a compound called α-amanitin, a toxin that inhibits transcription.
What would you predict to be the immediate outcome of adding α -amanitin to a cell?
a. reduced DNA synthesis
b. reduced production of one or more types of RNA
c. reduced binding of tRNAs to anticodons
d. reduced activity of ribosomes translating mRNA
Expert Solution & Answer
![Check Mark](/static/check-mark.png)
Want to see the full answer?
Check out a sample textbook solution![Blurred answer](/static/blurred-answer.jpg)
Students have asked these similar questions
1)You add a drug to cells that can pass through hydrophilic or hydrobic environments (e.g., membranes & cytosol). The drug specifically prevents the binding of KDEL (ER retention signal) to any other molecules. In the short term, what would happen to the synthesis and localization of translocon proteins?
a. New complete translocon proteins would be made, but they would end up in the golgi apparatus.
b. New complete translocon proteins would be made, but they would end up at the plasma membrane
c. No new intact translocon proteins would be synthesized
d. New complete translocon proteins would be made, but they would be secreted
e. New complete translocon proteins would be made and localized normally
The structure of a prodrug used for treating people with HIV virus (human immunodeficiency virus) and AIDS is shown below. This molecule is a precursor of a protease inhibitor that competitively inhibits HIV protease due to its resemblance to the proteolytic site of the enzyme. Which process in the viral life cycle does this inhibitor target directly ?
Group of answer choices
a. viral protein processing for making new viruses
b. viral mRNA synthesis
c. viral DNA integration into the host cell DNA
d. viral DNA synthesis
What is the role of ribosomes in protein synthesis? *
A. they carry proteins to the site of action
B. they provide a source of amino acids
C. they provide a site from tRNAs to link to mRNAs
D. they translate the basic DNA code using tRNA
Consider the following DNA bases sequence 3' TAT CGG 5'. what dipeptide is formed if a DNA point mutation converts CGG to CGT? *
A. Val-Ala
B. Asp-Glu
C. Ala- Ala
D. Gly-Ala
A tRNA molecule possesses the anticodon 5' CGU 3' , which amino acid will this tRNA molecule carry? *
A. Threonine
B. Valine
C. Alanine
D. Arginine
What will most likely be the effect of the change in the DNA molecule? *
A. the change will cause a harmful mutation
B. the DNA molecule will be unable to replicate…
Chapter 17 Solutions
Biological Science (7th Edition)
Ch. 17 - Prob. 1TYKCh. 17 - Prob. 3TYKCh. 17 - Prob. 4TYKCh. 17 - 5. RNases and proteases are enzymes that destroy...Ch. 17 - Prob. 6TYUCh. 17 - The nucleotide shown below is called cordycepin...Ch. 17 - Prob. 10TYPSSCh. 17 - What better not be for dinner? Eating even a...Ch. 17 - 12. α-Amanitin inhibits transcription by binding...Ch. 17 - Prob. 13PIAT
Knowledge Booster
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.Similar questions
- 1. "Interferons (IFNs)‐α and ‐β are expressed in response to a virus infection and are released from the cell in which they are produced. IFNs induce an antiviral state in other neighboring cells. a. Which cellular process is inactivated when IFN‐treated cells are infected with a virus? b. One arm of the IFN‐induced antiviral state is the synthesis of 2′,5′‐oligoA in response to viral infection. In one sentence or a simple diagram, what is the effect of this on the cell? c. Another arm of the IFN‐induced antiviral state is activation of the protein kinase in response to viral infection. In one sentence or a simple diagram, what is the effect of this on the cell? d. All cells contain the genes for IFNs. IFN synthesis is stimulated by virus infection. Would you expect a cell that has been treated with IFN to synthesize IFN in response to a viral infection? Explain your answer."arrow_forwardtRNAs a. carry amino acids b. bind to the anticodon present in the mRNA c. adapt the genetic information to the ribosome d. catalyze the peptide bondarrow_forwardSynthesis of new molecules of deoxyribonucleic acid is the process of A. replication B. translation C. transcription D. ossification E. cytokinesisarrow_forward
- One of the following is CORRECT: a. By each cycle the polypeptide has grown by one residue and consumed four GTP b. Peptidyl transferase mediates the release of amino acids from the growing chain c. Elongation process involves the addition of amino acids to the carboxyl end of the growing polypeptide chain d. Ribosomal RNAs are translated into proteinsarrow_forwardBased on its molecular structure what would you expect to be the biological mechanism of the hypothetical anti-cancer drug shown below. OH OMe OMe ö HỌ HỌ Please choose one: a. DNA intercalation b. Dihydrofolate reductase inhibition c. DNA strand breaking D. DNA alkylation to Estrogen eceptor modulationarrow_forwardThe addition of the poly-A tail adds more than 200 units of adenine to the strand of mRNA, yet no protein has a continuous line of more than 200 phenylalanines in its structure. Why is this so? A. RNA splicing occurs and removes the noncoding sequences. B. The poly-A tail and 5' GTP cap do not translate into proteins. C. The adenines are reabsorbed by the cell and help to form other forms of RNA. D. The tRNA does not recognize the poly-A tail.arrow_forward
- Which of the following statements below is incorrect? * A. the genetic code is overlapping B. the genetic code is universal C. degenerate codon specify the same amino acids D. the genetic code is triplet Which protein can break covalent bond? * A. Helicase B. Primase C. SSB D. DNA gyrase What is the complementary hnRNA base sequence produced from the DNA base sequence 5' C-T-A-T-A-C 3'? * A. 3' C-A-T-A-T-C 5' B. 3' G-A-T-A-T-G 5' C. 3' G-A-U-A- U-G 5' D. 3' C-U-A-U-A-G 5' Which of the following statements concerning the " cloverleaf" shape of tRNA molecules is correct? * A. four hairpin loops are present B. three hairpin loops and one open end are present C. two hairpin loops and two open ends are present…arrow_forwardWhich of the following statements about ribosomes is correct? * a. the number of ribosomes in a cell seldom exceeds 50 b. the active site of a ribosome contains mostly protein molecules c. structurally, ribosomes have two rRNA- protein subinuts d. no correct response What is the complementary hnRNA base sequence produced from the DNA base sequence 5' C-T-A-T-A-C 3' ? * a. 3' C-T-A-G-A-T 5' b. 3' C-G-G-A-T-A 5' c. 3' G-A-U-A-U-G 5' d. 3' G-A-T-A-T-G 5' The product of the first phase in protein synthesis is * a. DNA molecules b. RNA molecules c. both RNA and DNA molecules d. neither RNA and DNA moleculesarrow_forwardWhat statement is FALSE regarding the molecule ppGpp? 1.This molecule is a bacterial second messenger. 2. This molecule is produced in response to low concentrations of amino acids. 3.This molecule acts as an inhibitor of RNA polymerase. 4.This molecule is produced directly from GTP and ATP. 5.This molecule will reduce the synthesis of rRNA.arrow_forward
- 1.1 What is the best description of a Ribosome? a. An enzyme that uses ribose to synthesize amino acids b. A protein/RNA complex that synthesizes protein c. A ribozyme that uses RNA as an enzyme to directly ligate free amino acids to tRNAs d. A multi-subunit protein complex that charges tRNA with amino acids 1.2 In RNA processing? A. Exons are added to the ends of mRNA for protection B. Intron sequences are removed before the mRNA is translated C. The RNA transcript that leaves the nucleus may be much longer than the original primary transcript D. All RNA transcripts will be processed and leave the nucleus.arrow_forwardYou plan to synthesize a peptide to be used as a vaccine to treat melanoma, a particularly aggressive form of skin cancer. Normally, gp100, a protein on the surface of melanocytes, activates cell growth when it is bound by its ligand. Activation of the growth pathway depends on the presence of threonine in the ligand. The effective peptide vaccine will mimic the natural ligand, but won’t cause cell growth and division. Below is the sequence of the natural ligand: LDMKTAG In order to ensure your newly designed peptide vaccine does not cause cell growth upon binding, you must substitute the Threonine residue at position 5. What amino acid would you replace it with, bearing in mind that the peptide should still be similar enough to bind to the gp100 protein in the surface of melanocytes. Explain your choice. Your vaccine will be administered as a topical cream, and you require your peptide to have an overall neutral charge in order to be functional. At what pH should you formulate…arrow_forwardChaperones are: please explain the answer a.proteins that promote proper amino acid incorporation b.proteases that degrade improperly folded proteins c.proteins that promote proper polypeptide folding d.proteases that degrade improperly coded polypeptide chains e,proteins that promote rRNA stabilityarrow_forward
arrow_back_ios
SEE MORE QUESTIONS
arrow_forward_ios
Recommended textbooks for you
- Human Anatomy & Physiology (11th Edition)BiologyISBN:9780134580999Author:Elaine N. Marieb, Katja N. HoehnPublisher:PEARSONBiology 2eBiologyISBN:9781947172517Author:Matthew Douglas, Jung Choi, Mary Ann ClarkPublisher:OpenStaxAnatomy & PhysiologyBiologyISBN:9781259398629Author:McKinley, Michael P., O'loughlin, Valerie Dean, Bidle, Theresa StouterPublisher:Mcgraw Hill Education,
- Molecular Biology of the Cell (Sixth Edition)BiologyISBN:9780815344322Author:Bruce Alberts, Alexander D. Johnson, Julian Lewis, David Morgan, Martin Raff, Keith Roberts, Peter WalterPublisher:W. W. Norton & CompanyLaboratory Manual For Human Anatomy & PhysiologyBiologyISBN:9781260159363Author:Martin, Terry R., Prentice-craver, CynthiaPublisher:McGraw-Hill Publishing Co.Inquiry Into Life (16th Edition)BiologyISBN:9781260231700Author:Sylvia S. Mader, Michael WindelspechtPublisher:McGraw Hill Education
![Text book image](https://www.bartleby.com/isbn_cover_images/9780134580999/9780134580999_smallCoverImage.gif)
Human Anatomy & Physiology (11th Edition)
Biology
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:PEARSON
![Text book image](https://www.bartleby.com/isbn_cover_images/9781947172517/9781947172517_coverImage_Textbooks.gif)
Biology 2e
Biology
ISBN:9781947172517
Author:Matthew Douglas, Jung Choi, Mary Ann Clark
Publisher:OpenStax
![Text book image](https://www.bartleby.com/isbn_cover_images/9781259398629/9781259398629_smallCoverImage.gif)
Anatomy & Physiology
Biology
ISBN:9781259398629
Author:McKinley, Michael P., O'loughlin, Valerie Dean, Bidle, Theresa Stouter
Publisher:Mcgraw Hill Education,
![Text book image](https://www.bartleby.com/isbn_cover_images/9780815344322/9780815344322_smallCoverImage.gif)
Molecular Biology of the Cell (Sixth Edition)
Biology
ISBN:9780815344322
Author:Bruce Alberts, Alexander D. Johnson, Julian Lewis, David Morgan, Martin Raff, Keith Roberts, Peter Walter
Publisher:W. W. Norton & Company
![Text book image](https://www.bartleby.com/isbn_cover_images/9781260159363/9781260159363_smallCoverImage.gif)
Laboratory Manual For Human Anatomy & Physiology
Biology
ISBN:9781260159363
Author:Martin, Terry R., Prentice-craver, Cynthia
Publisher:McGraw-Hill Publishing Co.
![Text book image](https://www.bartleby.com/isbn_cover_images/9781260231700/9781260231700_smallCoverImage.gif)
Inquiry Into Life (16th Edition)
Biology
ISBN:9781260231700
Author:Sylvia S. Mader, Michael Windelspecht
Publisher:McGraw Hill Education
QCE Biology: Introduction to Gene Expression; Author: Atomi;https://www.youtube.com/watch?v=a7hydUtCIJk;License: Standard YouTube License, CC-BY