Biological Science (7th Edition)
7th Edition
ISBN: 9780134678320
Author: Scott Freeman, Kim Quillin, Lizabeth Allison, Michael Black, Greg Podgorski, Emily Taylor, Jeff Carmichael
Publisher: PEARSON
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Chapter 17, Problem 4TYK
Summary Introduction
Introduction:
In eukaryotes, the poly (A) tail at the 3’ (3-prime) end of the pre-mRNA (pre-messenger ribonucleic acid) stabilizes the mRNA. The mRNA is protected from enzymatic degradation in the cytoplasm by the presence of poly (A) tail at the end of the mRNA sequence. This poly (A) tail also helps in the movement of mRNA from the nucleus to the cytosol and promotes the mRNA translation by the ribosomes.
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A geneticist induces a mutation in eukaryote cells. The mutation results in an inability to form the poly(A) tail during processing of pre-mRNA. What does this mean for the mature mRNA and what will be the effect on these cells?
Possible Answers:
A. The mRNA will be spliced, but will not have a 5' cap.
B. The mRNA will likely be degraded.
C. The mRNA will not be cleaved.
D. The mRNA will have too many Gs and Cs.
Which of the following statements about RNA processing in eukaryotes is INCORRECT?
A. The excision of introns from pre-mRNA is the only modification required to produce a mature mRNA.
B. A protein/RNA complex is used to remove introns from the pre-mRNA.
C. A poly A tail is added on to the 3′ end of the mRNA.
D. A 7-methylguanosine cap is added on to the 5′end of the mRNA.
E. Modification occurs in the nucleus.
The addition of the poly-A tail adds more than 200 units of adenine to the strand of mRNA, yet no protein has a continuous line of more than 200 phenylalanines in its structure. Why is this so?
A. RNA splicing occurs and removes the noncoding sequences.
B. The poly-A tail and 5' GTP cap do not translate into proteins.
C. The adenines are reabsorbed by the cell and help to form other forms of RNA.
D. The tRNA does not recognize the poly-A tail.
Chapter 17 Solutions
Biological Science (7th Edition)
Ch. 17 - Prob. 1TYKCh. 17 - Prob. 3TYKCh. 17 - Prob. 4TYKCh. 17 - 5. RNases and proteases are enzymes that destroy...Ch. 17 - Prob. 6TYUCh. 17 - The nucleotide shown below is called cordycepin...Ch. 17 - Prob. 10TYPSSCh. 17 - What better not be for dinner? Eating even a...Ch. 17 - 12. α-Amanitin inhibits transcription by binding...Ch. 17 - Prob. 13PIAT
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- Transcription in prokaryotes produces mRNA that is ready to translate, while in eukaryotes the RNA must be processed by... A. Adding a 5' cap, which is a version of a guanine nucleotide B. Adding a 3' poly A tail, which is a series of adenosines C. Removing introns D. A and B E. A, B, and Carrow_forwardThere are 61 mRNA codons that specify an amino acid, but only 45 tRNAs. This is best explained by the fact that A. some tRNAs have anticodons that recognize two or more different codons. B. the rules for base pairing between the third base of a codon and tRNA are flexible. C. many codons are never used, so the tRNAs that recognize them are dispensable. D. A and B only E. A, B, and Carrow_forwardIf you imagine a messenger RNA molecule in the cytoplasm of a cell, which of the following will likely affect how much protein is made by translation of this message? A. The presence of appropriate snRNPs. B. The length of the polyA tail. C. The strength of hydrogen bonds holding the mRNA to ribosomal RNA. D. The ability of the mRNA to pair with itself to form a helix-turn-helix structure.arrow_forward
- Which of the following is TRUE in translation? A. Amino acyl TRNA containing one amino acid is attached to the P site B. Amino acids/peptides attached to the amino acyl tRNA at the P site are transferred to amino acids at the A site, followed by translocation. C. Empty TRNAS are immediately released from the ribosomes D. The E site is always empty after translocation to receive incoming empty TRNAS. E. The anticodon binding to the codon is stringent, i.e. there must be complete complementary base-pairing between the bases in the codon and anticodon before translation can proceed.arrow_forwardWhat is one function of the 5' cap in eukaryotic mRNA? Select one: a. It is involved in translation termination. b. It is an intron splicing signal. c. It is the initial attachment site for ribosomes. d. It is involved in polyadenylation of the 5' end of the mRNAarrow_forwardDuring translation, when a stop codon is read on the mRNA strand at the ribosome... a the mRNA is digested by a protease complex b a repressor attached to the ribosome that inhibits the movement of the ribosome along the mRNA c the enzyme helicase binds to terminate the polypeptide d a release factor enters the A site of the ribosome and stimulates the disassembly of the translation complex Codons are... a triplets coding for a single amino acid. b redundant in their coding for various amino acids. c matched with anticodons during translation d triplets found on transfer RNA Question 6 (1 point) In order to produce many copies of the same protein in a short period of time, the cell uses... a intron self-splicing. b many RNA polymerase molecules to produce multiple mRNA transcripts at the same time. c single-unit ribosomes for high speed translation. d codon-anticodon reciprocal…arrow_forward
- During the processing of pre-mRNA in eukaryotes Select one: a. Exons are joined together using polyadenylate polymerase b. The spliceosome breaks covalent bonds at 5' and 3' splice sites c. A 5'methyl cytosine cap is added using specific enzyme d. A 3'-poly-A tail is attached using an unusual 5'-5 ester linkagearrow_forwardIf an MRNA is alternatively spliced, then different introns are removed from a pre-MRNA, producing transcripts that will potentially encode proteins with different primary structures. I. the MRNA is found in a bacterial cell. II. transcription and translation of the MRNA will occur simultaneously. the alternative splicing happened in the cytoplasm. IV. Ay different exons from a pre-mRNA will be spliced together. V. the different MRNAS will all have poly-A tails. VI.arrow_forwardWhat would be the direct consequence to a cell of loss-of-function of Elongation Factor-Tu (EF-Tu)? You may select multiple answers. a. tRNAs would fail to exit the E site after giving up their amino acid. b. The error rate of translation would increase. c. The ribosome would frequently fail to identify the correct start codon and initiation of translation would become less efficient. d. There would be no pause between the entry of a tRNA into the A site and peptidyl transfer.arrow_forward
- tRNAs a. carry amino acids b. bind to the anticodon present in the mRNA c. adapt the genetic information to the ribosome d. catalyze the peptide bondarrow_forwardWhich of the following statements is INCORRECT? a. In simultaneous transcription of mRNA, many messenger RNA may be transcribed from different DNA strand happening all at once. b. All of the following statements are incorrect c. A poly A - tail is added at the end of the 3’ base. d. In eukaryotic cells, messenger RNA must exit the nucleus and enter the cytoplasmarrow_forwardFor each of the following, identify the type of RNA involved (mRNA, rRNA, or tRNA). a. Transports the correct amino acid to the ribosome, using the information encoded in the mRNA. b. Is a major component of ribosomes. c. Specifies the order of amino acids in a protein, using a series of three-base codons, where different amino acids are specified by particular codons. d. Contains a three-base anticodon that pairs with a complementary codon revealed in the mRNA. e. Assists in making the bonds that link amino acids together to make a protein.arrow_forward
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