BIOL 308: BIOL-MSTBIO NEW DSGN ACCESS
BIOL 308: BIOL-MSTBIO NEW DSGN ACCESS
18th Edition
ISBN: 9781323838877
Author: Campbell
Publisher: Pearson Custom Publishing
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Chapter 17, Problem 11TYU

scientific inquiry Knowing that the genetic code is almost universal, a scientist uses molecular biological methods to insert the human β-globin gene (shown in Figure 17.12) into bacterial cells, hoping the cells will express it and synthesize functional β-globin protein. Instead, the protein produced is nonfunctional and is found to contain many fewer amino acids than does β-globin made by a eukaryotic cell. Explain why.

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One remarkable feature of the genetic code is that amino acids with similar chemical properties often have similar codons. thus codons with U or C as the second nucleotide tend to specify hydrophobic amino acids. Can you suggest a possible explanation for this phenomenon in terms of the early evolution of the protein-synthesis machinery?
Knowing that the genetic code is almost universal, a scientist uses molecular biological methods to insert the human β-globin gene (Shown in Figure 17.11) into bacterial cells, hoping the cells will express it and synthesize functional β-globin protein. Instead, the protein produced is nonfunctional and is found to contain many fewer amino acids than does β-globin made by a eukaryotic cell. Explain why.
EVOLUTION CONNECTION Most amino acids are coded forby a set of similar codons (see Figure 17.6). Propose at least oneevolutionary explanation to account for this pattern.

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BIOL 308: BIOL-MSTBIO NEW DSGN ACCESS

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