NESTER'S MICROBIOLOGY-ACCESS
NESTER'S MICROBIOLOGY-ACCESS
9th Edition
ISBN: 9781260518498
Author: Anderson
Publisher: MCG
bartleby

Concept explainers

Question
Book Icon
Chapter 17, Problem 2MC
Summary Introduction

Introduction:

ABO blood grouping was first discovered by Carl Landsteiner. This system is used to denote the presence of one, both, or neither of the A and B antigens on erythrocytes. In a humantransfusion, it is the most important of the 36 classification systems. A mismatched transfusion can cause serious potentially fatal adverse reactions. If an individual receives a mismatched transfusion of red blood cells with different antigens, it causes a transfusion reaction resulting in clumping, when antibodies bind to those cells. These cells are destroyed by releasing hemoglobin in the bloodstream, thus blocking blood vessels kidneys and other body organs.

Table: ABO Blood group antigens present on RBC and IgM antibodies present in serum

GROUP A GROUP B GROUP AB GROUP O
RED BLOOD CELL TYPE A B AB O
Antibodies in plasma Anti-B Anti-A NONE Anti-A and Anti-B
Antigens in RBC A antigen B antigen A and B antigens none

Blurred answer
Students have asked these similar questions
Which, if any, of the following statements is incorrect?a) Each person makes many millions of different HLA proteins so as to be able to recognize and bind foreign antigens.b) Classical HLA proteins are highly polymorphic; non-classical HLA proteins show very limited polymorphism.c) Classical class I HLA proteins are displayed on the surface of very few cell types, notably immune system cells.d) HLA proteins are the most polymorphic human proteins.
A person with type A+ blood gets a transfusion with type O- blood. What is most likely to happen to the recipient? A) The recipient's blood will agglutinate (clump) due to the presence of natural antibodies in the recipient's blood. B) Nothing because the donor's blood is compatible with the recipient's blood. C) The recipient's blood will agglutinate (clump) due to the presence of natural antigens on the recipient's blood cells.
Even though instances of fetal, maternal ABO, incompatibility are common, severe hemolytic disease due to ABO incompatibility is rare. Which of the following best explains this difference? A) ABO incompatibility causes extensive extra medullary hematopoiesis B) antibodies against ABO antigens do not bind complement C) the maternal immune system is tolerant to ABO ANTIGENS D) most anti- A or anti- B antibodies are of IgM type and do not cross the placenta E) the presence of concurrent Rh incompatibility decreases the immunogenicity of erythrocytes
Knowledge Booster
Background pattern image
Biology
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.
Similar questions
SEE MORE QUESTIONS
Recommended textbooks for you
Text book image
Human Anatomy & Physiology (11th Edition)
Biology
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:PEARSON
Text book image
Biology 2e
Biology
ISBN:9781947172517
Author:Matthew Douglas, Jung Choi, Mary Ann Clark
Publisher:OpenStax
Text book image
Anatomy & Physiology
Biology
ISBN:9781259398629
Author:McKinley, Michael P., O'loughlin, Valerie Dean, Bidle, Theresa Stouter
Publisher:Mcgraw Hill Education,
Text book image
Molecular Biology of the Cell (Sixth Edition)
Biology
ISBN:9780815344322
Author:Bruce Alberts, Alexander D. Johnson, Julian Lewis, David Morgan, Martin Raff, Keith Roberts, Peter Walter
Publisher:W. W. Norton & Company
Text book image
Laboratory Manual For Human Anatomy & Physiology
Biology
ISBN:9781260159363
Author:Martin, Terry R., Prentice-craver, Cynthia
Publisher:McGraw-Hill Publishing Co.
Text book image
Inquiry Into Life (16th Edition)
Biology
ISBN:9781260231700
Author:Sylvia S. Mader, Michael Windelspecht
Publisher:McGraw Hill Education