Campbell Biology (11th Edition)
Campbell Biology (11th Edition)
11th Edition
ISBN: 9780134093413
Author: Lisa A. Urry, Michael L. Cain, Steven A. Wasserman, Peter V. Minorsky, Jane B. Reece
Publisher: PEARSON
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Chapter 17.3, Problem 3CC
Summary Introduction

To determine: The effect on the cells that are treated with an agent which caused the removal of cap from messenger RNAs (mRNAs).

Concept introduction:

After transcription, pre-mRNA is synthesized and further modified before translation in the cytoplasm. This is called the RNA processing and it includes the modification of mRNA ends and RNA splicing. A modified guanine (7-methyl guanine) group is added to the 5′ end of the mRNA chain with the help of the capping enzymes. This is known as the 5′ cap. At the 3′ end of the eukaryotic mRNA chain, adenine groups (poly-A tail) are added by poly (A) polymerase enzyme. This is known as the polyadenylation.

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WHAT IF? Suppose the mRNA being degraded in Figure18.14 coded for a protein that promotes cell division ina multicellular organism. What would happen if a mutation disabled the gene for the miRNA that triggers thisdegradation?
Q.) A.)Search in human genome if any examples of mRNA translated from 2 different sites?and give examples? B.)aminoacyl tRNA synthetase is specialized or not ? And why?
WHAT IF? In eukaryotic cells, mRNAs have been foundto have a circular arrangement in which proteins holdthe poly-A tail near the 5¿ cap. How might this increasetranslation efficiency?

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Campbell Biology (11th Edition)

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