Chapter 18, Problem 18.109GP

Interpretation Introduction

Interpretation:

Solubility property in water should be explained when Peptide containing alanine and leucine or a peptide containing lysine and aspartic acid.

Concept introduction:

• Many amino acids are linked together through amide bonds to form a biologically large molecule known to be proteins.
• Amino functional group is $(-N{H}_2)$ and carboxyl functional group is $(-COOH)$ and a $R$ (alkyl) group is considered as side chain, when all these are bonded to same carbon atom.
• In protein the amide bond can link together with two amino acids to form a peptide bond ($O=C-NH-$).
• Dipeptide results from the linkage of two amino acids through one peptide bond.
• Tertiary structure of protein is the noncovalent interaction that holds the single protein in a three dimensional shape takes place primarily between amino acid side chain or side chain thiol groups.
• Hydrocarbon side chain are attracted to each other by dispersion forces caused as a result of uneven distribution of electrons give rise to hydrophobic interaction.
• Hydrogen bonding is the electrostatic force of attraction between hydrogen and the electronegative atom.