Principles of General, Organic, Biological Chemistry
Principles of General, Organic, Biological Chemistry
2nd Edition
ISBN: 9780073511191
Author: Janice Gorzynski Smith Dr.
Publisher: McGraw-Hill Education
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Chapter 18, Problem 18.51AP

(a)

Interpretation Introduction

Interpretation:

Chemical equation for conversion of fructose1,6-biphosphate to fructose6-phosphate has to be written.

Concept Introduction:

Nucleotide is defined as basic unit for formation of nucleic acid that is essential for completion of metabolic reactions in body. The three basic components of nucleotide are as follows:

1. Nitrogen-containing base

2. Pentose sugar

3. Phosphate group

Examples of nucleosides are GTP and ATP. Nucleotide on hydrolysis releases energy by cleavage of phosphoanhydride bond. The reaction of hydrolysis of ATP is as follows:

  ATP+H2OADP+Pi+energy

(b)

Interpretation Introduction

Interpretation:

Whether energy is released or absorbed in formation of fructose6-phosphate by fructose1,6-biphosphate has to be determined.

Concept Introduction:

Refer to part (a).

(c)

Interpretation Introduction

Interpretation:

Whether reaction is energetically favorable or not in formation of fructose6-phosphate by fructose1,6-biphosphate has to be determined.

Concept Introduction:

Refer to part (a).

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Write a balanced chemical equation for the pentose phosphate pathway in the first two modes depicted in Figure , where (a) ribose-5-phosphate synthesis is maximized and (b) NADPH production is maximized, by conversion of the sugar phosphate products to glucose-6-phosphate for repeated operations of the pathway
Draw the mechanism for the third reaction in glycolysis—the reaction of fructose-6-phosphate with ATP to form fructose-1,6-bisphosphate.
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