CAMPBELL BIO TXT+MOD.MAST.BIO W ETEXT
10th Edition
ISBN: 9781323257937
Author: Reece
Publisher: PEARSON C
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Chapter 18, Problem 18.5CR
Compare the usual functions of proteins encoded by proto-oncogenes with those of proteins encoded by tumor-suppressor genes.
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Compare and contrast the genetic defects that can lead to disruption of a tumor suppressor gene compared to the mechanisms for activation of oncogenes.
Compare and contrast oncogenes versus tumor-suppressorgenes.
Cancer-promoting mutations are likely to have different effects on the activity of proteins encoded byproto-oncogenes than they do on proteins encodedby tumor-suppressor genes. Explain.
Chapter 18 Solutions
CAMPBELL BIO TXT+MOD.MAST.BIO W ETEXT
Ch. 18.1 - How does binding of the trp corepressor to the trp...Ch. 18.1 - Describe the binding of RNA Polymerase,...Ch. 18.1 - WHAT IF? A certain mutation in E. coli changes...Ch. 18.2 - In general, what are the effects of histone...Ch. 18.2 - Compare the roles of general and specific...Ch. 18.2 - WHAT IF? Suppose you compared the nucleotide...Ch. 18.2 - Once mRNA encoding a particular protein reaches...Ch. 18.3 - Compare miRNAs and siRNAs, including their...Ch. 18.3 - WH AT IF? Suppose the mRNA being degraded in...Ch. 18.4 - MAKE CONNECTIONS As you learned in Chapter 12,...
Ch. 18.4 - MAKE CONNECTIONS Explain how the signaling...Ch. 18.4 - How do fruit fly maternal effect genes determine...Ch. 18.4 - Prob. 4CCCh. 18.5 - MAKE CONNECTIONS The p53 protein can activate...Ch. 18.5 - Under what circumstances is cancer considered to...Ch. 18.5 - Prob. 3CCCh. 18 - Compare and contrast the roles of a corepressor...Ch. 18 - Describe what must happen in a cell for a gene...Ch. 18 - Why are miRNAs called noncoding RNAs? Explsin how...Ch. 18 - Describe the two main processes that cause...Ch. 18 - Compare the usual functions of proteins encoded by...Ch. 18 - If a particular operon encodes enzymes for making...Ch. 18 - Muscle cells differ from nerve cells mainly...Ch. 18 - The functioning of enhancers is an example of (A)...Ch. 18 - Cell differentiation always involves (A)...Ch. 18 - Which of the following is an example of...Ch. 18 - What would occur if the repressor of an inducible...Ch. 18 - Absence of bicoid in mRNA from a Drosophila egg...Ch. 18 - Which of the following statements about the DNA in...Ch. 18 - Within a cell, the amount of protein made using a...Ch. 18 - Prob. 10TYUCh. 18 - Prob. 11TYUCh. 18 - Prob. 12TYUCh. 18 - Prob. 13TYUCh. 18 - Prob. 14TYUCh. 18 - WRITE ABOUT A THEME: INTERACTIONS In a Short essay...Ch. 18 - SYNTHESIZE YOUR KNOWLEDGE The flashlight fish has...
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- What is the difference between a proto-oncogene and a tumor-suppressor gene?arrow_forward________ are changes to the nucleotides in a segment of DNA that codes for a protein. a. Proto-oncogenes b. Tumor suppressor genes c. Gene mutations d. Negative regulatorsarrow_forwardExplain the difference between a proto-oncogene and a tumor-suppressor gene.arrow_forward
- Explain in general what is meant by a proto-oncogene and how they are involved in the formation of a tumorarrow_forwardDescribe the genetic changes that inactivate tumor-suppressor genes.arrow_forwardClassify the following genes as proto-oncogenes or tumor-suppressor genes: p53, ras, Bcl-2, telomerase, jun, andarrow_forward
- What is the difference between an oncogene and a tumor-suppressorgene? Give two examples of each type of gene.arrow_forwardExplain how mutations in oncogenes and in tumor suppressorgenes cause cancer.arrow_forwardDescribe, using specific examples, the differences in how a growth factor gene and a tumor suppressor gene can become oncogenes.arrow_forward
- "In the cellular regulatory pathways that control cell growth and proliferation, the products of oncogenes are stimulatory components and the products of tumor suppressor genes are inhibitory components" is true or false.arrow_forwardDistinguish between proto-oncogenes and tumor-suppressor genes. To become cancer promoting, do proto-oncogenes and tumor-suppressor genes undergo gain-of-function or loss-of-function mutations? Classify the following genes as proto-oncogenes or tumor-suppressor genes: p53, ras, BCL-2, JUN, MDM2, and p16.arrow_forwardExplain why many oncogenic viruses contain genes whose products interact with tumor-suppressor proteins.arrow_forward
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