Biological Science (6th Edition)
6th Edition
ISBN: 9780321976499
Author: Scott Freeman, Kim Quillin, Lizabeth Allison, Michael Black, Emily Taylor, Greg Podgorski, Jeff Carmichael
Publisher: PEARSON
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Question
Chapter 19, Problem 7TYU
Summary Introduction
To review:
The activity of the drug inhibiting the histone deacetylase (HDAC) on the gene expression.
Introduction:
The deoxyribonucleic acid (DNA) must be separated from the histone proteins for the ribonucleic acid (RNA) polymerases to get attach to DNA template for initiation of transcription.
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(a) Describe how dna binding proteins contact the dna
(b)How does the acetylation of lysines on the N-terminal tails of histones influences gene expression?
New drugs are being developed that decrease DNA methylation and prevent the removal of acetyl groups from histone Explain how these drugs could affect gene expression to help kill tumor cells.
Explain how methylation of cytosine nucleotides can affect gene expression in one way.
Explain how methylation of histone proteins can affect gene expression in one way.
Chapter 19 Solutions
Biological Science (6th Edition)
Ch. 19 - What is chromatin? a. the histone-containing...Ch. 19 - Prob. 2TYKCh. 19 - Prob. 3TYKCh. 19 - Prob. 4TYKCh. 19 - Compare and contrast the items in each pair: (a)...Ch. 19 - Prob. 6TYUCh. 19 - Prob. 7TYUCh. 19 - Prob. 8TYUCh. 19 - Prob. 9TYPSSCh. 19 - 10. QUANTITATIVE Imagine repeating the experiment...
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Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.Similar questions
- Which statement regarding UTRs is TRUE? a) Transcription begins at the start of the 5' UTR b) Translation begins at the start of the 5' UTR c) The 5' and 3' UTRs are spliced from the mRNA transcript d) The translation stop codon is found downstream of the 3' UTRarrow_forwarda) Define the term gene expression b) State 4 difference between prokaryotes and eukaryotes gene expression c) state the importance of regulating gene expressionarrow_forwardNew drugs are being developed that decrease DNA methylation and prevent the removal of acetyl groups from histone proteins. Explain how these drugs could affect gene expression to help kill tumor cells.arrow_forward
- Post-translational control refers to: a. regulation of gene expression after transcription b. regulation of gene expression after translation c. control of epigenetic activation d. period between transcription and translationarrow_forwardBriefly describe how transcription works and show that you understand the difference between transcription of a gene located on the upper strand and transcription of a gene located on the lower strand Transcription occurs when DNA becomes RNA using RNA polymerase that copies DNA to mRNAarrow_forwardExplain how the genetic code is used in the expression of a gene.arrow_forward
- Describe the role of DNA methylation in gene expression in mammalian cells.arrow_forwardCompare and contrast oncogenes and supressor genes. Give an example of a gene of each kind and a cancer type associated with mutations in said gene.arrow_forwardWhich is the expected outcome following the deacetylation of histones? a) Coiling of chromatin, preventing it from being accessed by transcriptional machinery b) Coiling of chromatin, allowing it to be accessed by transcriptional machinery c) Uncoiling of chromatin, preventing it from being accessed by transcriptional machinery d) Uncoiling of chromatin, allowing it to be accessed by transcriptional machineryarrow_forward
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