(a)
Interpretation:
The synthesis of the given compound using direct alkylation is to be stated.
Concept introduction:
(b)
Interpretation:
The synthesis of the given compound using direct alkylation is to be stated.
Concept introduction:
Amine alkylation is the reaction in which an alkyl halide reacts with ammonia or an amine. This is a type of nucleophilic aliphatic substitution. Exhaustive alkylation of an amine leads to the successive substitution of a hydrogen by an alkyl group and the formation of quaternary ammonium salt takes place.
(c)
Interpretation:
The synthesis of the given compound using direct alkylation is to be stated.
Concept introduction:
Amine alkylation is the reaction in which an alkyl halide reacts with ammonia or an amine. This is a type of nucleophilic aliphatic substitution. Exhaustive alkylation of an amine leads to the successive substitution of a hydrogen by an alkyl group and the formation of quaternary ammonium salt takes place.
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ORGANIC CHEMISTRY MASTERINGCHEM ACCESS
- Primary amines can also be prepared by the reaction of an alkyl halide with azide ion, followed by catalytic hydrogenation. What advantage do this method and the Gabriel synthesis have over the synthesis of a primary amine using an alkyl halide and ammonia?arrow_forwardPrimary amines can also be prepared by the reaction of an alkyl halide with azide ion, followed by catalytic hydrogenation. What advantage do this method and the Gabriel synthesis have over the synthesis of a primaryamine using an alkyl halide and ammonia?arrow_forwardhow to synthesize 2-phenylclohexanone from cyclohexanone?arrow_forward
- Provide an explanation (in detail) on how base catalysts speed up nucleophilic reactions of carbonyl compounds.arrow_forwardGive the shortest route to produce the desired products 1. cyclobutanoic acid to ethyl-cyclobutyl ketone 2. 2-butanone to pentatonic acid 3. propane to butanaminearrow_forwardWhat product will be made with aqueous acid?arrow_forward
- Why can you not use this reaction to make a secondary amine? a) Alkyl halides are weak electrophiles.b) Primary amines are weak nucleophiles.c) The primary amine is too nucleophilic, so over-reaction will occur.d) The secondary amine product is more nucleophilic than the primary amine reactant, so over-reaction will occur.arrow_forwardWhich reagent(s) can be used to convert an aldehyde to a carboxylic acid? Choose all that apply. OH А. Jone's reagent and Tollen's reagent В. Sodium Borohydride С. Tollen's reagent D. PCC and Jone's reagent Е. O E. Grignard reagents and Lithium Aluminum Hydridearrow_forwardWhich of the following reaction or reagent does not produce an amine molecule? A. Curtius rearrangementB. Reaction of oximes with metallic sodium in ethanolC. Reaction of N-alkylphthalimide with hydrazineD. Hofmann transformationE. Wolff transformationarrow_forward
- Organic ChemistryChemistryISBN:9781305580350Author:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. FootePublisher:Cengage Learning