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The pH of human stomach acid ranges from 1.0 to 3.0, whereas a healthy esophagus has a pH of approximately 7.0. In gastroesophageal reflux disease (GERD), often called acid reflux, stomach acid flows backward from the stomach into the esophagus. Repeated episodes in which esophageal pH goes below 4.0, considered clinical acid reflux, can result in bleeding ulcers and damage to the esophageal lining. The data in the Figure, from a patient with GERD, show esophageal pH during a sleeping reflux event. How many minutes does it take to go from the peak of the reflux event (when pH is most acidic) to when the reflux event is over? Source: Based on T. Demeester et al. 1976. Patterns of gastroesophageal reflux in health and disease. Annals of Surgery 184:459–469.

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Biology: The Dynamic Science (Mind...

4th Edition
Peter J. Russell + 2 others
Publisher: Cengage Learning
ISBN: 9781305389892
BuyFind

Biology: The Dynamic Science (Mind...

4th Edition
Peter J. Russell + 2 others
Publisher: Cengage Learning
ISBN: 9781305389892

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Chapter 2, Problem 1ITD
Textbook Problem
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The pH of human stomach acid ranges from 1.0 to 3.0, whereas a healthy esophagus has a pH of approximately 7.0. In gastroesophageal reflux disease (GERD), often called acid reflux, stomach acid flows backward from the stomach into the esophagus. Repeated episodes in which esophageal pH goes below 4.0, considered clinical acid reflux, can result in bleeding ulcers and damage to the esophageal lining. The data in the Figure, from a patient with GERD, show esophageal pH during a sleeping reflux event.

Chapter 2, Problem 1ITD, The pH of human stomach acid ranges from 1.0 to 3.0, whereas a healthy esophagus has a pH of

How many minutes does it take to go from the peak of the reflux event (when pH is most acidic) to when the reflux event is over?

Source: Based on T. Demeester et al. 1976. Patterns of gastroesophageal reflux in health and disease. Annals of Surgery 184:459–469.

Expert Solution
Summary Introduction

To review:

The time pH takes to go from the peak of the reflux event to when the reflux event is finished, in case of GERD (gastroesophageal reflux disease) patient.

Introduction:

Gastroesophageal reflux disease is known to be a digestive disorder, which mainly affects the lower segment of esophageal sphincter, which is basically the ring of muscle found between the stomach and esophagus. It is also referred as acid reflex or digestive system disorder.

Explanation of Solution

The condition when pH (potential of hydrogen) of esophagus drops below 7, the reflux is said to occur. Reflux is that condition when hydrochloric acid in stomach reaches esophagus and decreases its pH from 7.0 (normal condition) to acidic (below 7.0)...

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