Genetics: From Genes to Genomes, 5th edition
5th Edition
ISBN: 9780073525310
Author: Leland H. Hartwell, Michael L. Goldberg, Janice A. Fischer, Leroy Hood, Charles F. Aquadro
Publisher: McGraw-Hill Education
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Textbook Question
Chapter 2, Problem 33P
For each of the following human pedigrees, indicate whether the inheritance pattern is recessive or dominant. What feature(s) of the pedigree did you use to determine the mode of inheritance? Give the genotypes of affected individuals and of individuals who carry the disease allele but are not affected.
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Cystic fibrosis (CF) is an autosomal recessive trait. A three-generation pedigree is shown below for a family that carries the mutant allele for cystic fibrosis. Note that carriers are not colored in to allow you to figure out their genotypes. Normal allele = F CF mutant allele = f
What is the genotype of individual #13?
A) ff
B) FF
C) Ff
D) it is impossible to tell
This pedigree (below) shows inheritance of a genetic disorder in a family. Assume the trait is
rare.
What is the mode of inheritance for this trait? [Select]
You know this because that mode of inheritance is characterized by:
[Select]
individuals who have the allele express it and
• An affected male parent passes the allele to [Select]
and [Select]
of his daughters.
• An affected female parent passes the allele to
sons and [Select]
[Select]
of her daughters.
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This pedigree (below) shows inheritance of a genetic disorder in a family. Assume the trait is
rare.
What is the mode of inheritance for this trait? [Select]
You know this because that mode of inheritance is characterized by:
[ Select]
• An affected male parent passes the allele to [Select]
and [Select]
individuals who have the allele express it and
and [Select]
of his daughters.
• An affected female parent passes the allele to [Select]
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Chapter 2 Solutions
Genetics: From Genes to Genomes, 5th edition
Ch. 2 - For each of the terms in the left column, choose...Ch. 2 - During the millennia in which selective breeding...Ch. 2 - Describe the characteristics of the garden pea...Ch. 2 - An albino corn snake is crossed with a...Ch. 2 - Two short-haired cats mate and produce six...Ch. 2 - Piebald spotting is a condition found in humans in...Ch. 2 - As a Drosophila research geneticist, you keep...Ch. 2 - A mutant cucumber plant has flowers that fail to...Ch. 2 - In a particular population of mice, certain...Ch. 2 - In humans, a dimple in the chin is a dominant...
Ch. 2 - Among Native Americans, two types of earwax...Ch. 2 - Imagine you have just purchased a black stallion...Ch. 2 - If you roll a die singular of dice, what is the...Ch. 2 - Prob. 14PCh. 2 - How many genetically different eggs could be...Ch. 2 - What is the probability of producing a child that...Ch. 2 - Prob. 17PCh. 2 - Galactosemia is a recessive human disease that is...Ch. 2 - Albinism is a condition in which pigmentation is...Ch. 2 - A cross between two pea plants, both of which grew...Ch. 2 - A third-grader decided to breed guinea pigs for...Ch. 2 - The self-fertilization of an pea plant produced...Ch. 2 - Prob. 23PCh. 2 - A pea plant from a pure-breeding strain that is...Ch. 2 - Prob. 25PCh. 2 - A pea plant heterozygous for plant height, pod...Ch. 2 - In the fruit fly Drosophila melanogaster, the...Ch. 2 - Prob. 28PCh. 2 - Considering the yellow and green pea color...Ch. 2 - Prob. 30PCh. 2 - Prob. 31PCh. 2 - Prob. 32PCh. 2 - For each of the following human pedigrees,...Ch. 2 - Consider the pedigree that follows for cutis laxa,...Ch. 2 - A young couple went to see a genetic counselor...Ch. 2 - Huntington disease is a rare fatal, degenerative...Ch. 2 - Is the disease shown in the following pedigree...Ch. 2 - Figure 2.22 shows the inheritance of Huntington...Ch. 2 - Prob. 39PCh. 2 - People with nail-patella syndrome have poorly...Ch. 2 - Midphalangeal hair hair on top of the middle...Ch. 2 - A man with Huntington disease he is heterozygous...Ch. 2 - Explain why disease alleles for cystic fibrosis CF...
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- For the pedigrees below, name the inheritance pattern of the depicted disorder: If more than one pattern is possible, name all possibilities. For any recessive disorder, clearly mark all individuals who must be carriers by placing a dot inside the corresponding circle or square. Assume that each disorder is rare (i.e. any individual "marrying into" the pedigree is normal and not carrying a mutant allele). A) I II III IV C) I II III IV 1 2 E) 몽 I II III IV B) D) I II III IV II III IV 3E% 2arrow_forwardThe following pedigree shows the pattern of inheritance for an uncommon human disease. Filled symbols indicate individuals with the disease: open symbols indicate normal individuals. Using the symbols A and a, answer the following questions about this pedigree. 1. What are the most probable genotypes of individuals II-9 and II-10 2. If individuals II-1 and II-2 have another child, what is the probability that it will have the disease?arrow_forwardUsing the pedigree chart, explain: a) The number of generations seen. b) If all blue-coloured shapes are affected with disease X- how many males are affected? how many females are affected? c) Does this disease have a dominant or recessive inheritance pattern? Justify your answer.arrow_forward
- The pedigree below traces the inheritance of Albinism, a genetic disorder. Affected individuals, indicated here by the colored gray circles and squares, are unable to make a normal amount of melanin, the chemical that is responsible for eye, skin, and hair color. Does Albinism appear to be caused by a dominant allele or by a recessive allele? Fill in the genotypes of the individuals whose genotypes can be deduced. What genotypes are possible for each of the other individuals? Explain!arrow_forwarda) Which of the four modes of inheritance are consistent with the disease shown in this human pedigrees below? (List the compatible mode or modes) Give an answer for a, b and c b) If the parents in pedigree c have 2 other children, what is the probability that they will carry the disease?arrow_forwardThe pedigree below tracks the inheritance of a genetic disorder through a family's generation. Determine the probable inheritance mode for the trait shown in the affected individual (the shaded symbols) by answering the following questions. I II 2 3 4 5 7 III 2 3 6 7 8 5 (i) Based on the pedigree, Y-linked inheritance can be excluded at a glance. Give your reason. (ii) What TWO (2) other modes of inheritance can be definitely excluded? Explain your answer. Of the remaining modes of inheritance, which is the most likely? Which is less likely? Explain your answers. (ii)arrow_forward
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