Concept explainers
Interpretation:The pH of lysine at isoelectric point needs to be determined.
Concept introduction:
The pH at which molecule does not carry any net electric charge is said to be its isoelectric point. In this case, it is electrically neutral and the amino acids do not migrate in an electric field.
Answer to Problem 153AE
The pH of lysine at isoelectric point is 6.07
Explanation of Solution
The equilibrium constant of reaction Key is known and the value is as follows:
This can be depicted as:
Considering the equation
The equilibrium constant can be represented as follows:
Since,
Thus,
Since,
Thus,
To compute the pH at isoelectric point is done below
Hence, the pH of glycine at isoelectric point is 6.07.
The pH of glycine at isoelectric point is 6.07.
Want to see more full solutions like this?
Chapter 21 Solutions
CHEM.PRINC.W/OWL2+REBATE+2 SUPPL.>IP<
- For the tripeptide SerArgIle which amino acid residues a. are hydrophilic b. are hydrophobic c. possess polar neutral R groups d. participate in two amide linkagesarrow_forward22-21 Explain why an amino acid cannot exist in an un-ionized form at any pH.arrow_forward22-49 Based on your knowledge of the chemical properties of amino acid side chains, suggest a substitution for leucine in the primary structure of a protein that would probably not change the character of the protein very much.arrow_forward
- Consider the tripeptide tyrosylleucylisoleucine. a. Specify its structure using three-letter symbols for the amino acids. b. How many peptide bonds are present within the peptide? c. Which of the amino acid residues has the largest R group? d. Which of the amino acid residues, if any, has an acidic side chain?arrow_forwardExplain why a protein is least soluble in an aqueous medium that has a pH equal to the isoelectric point of the protein.arrow_forwardConsider the tripeptide leucylvalyltryptophan. a. Specify its structure using three-letter symbols for the amino acids. b. How many peptide bonds are present within the peptide? c. Which of the amino acid residues has the largest R group? d. Which of the amino acid residues, if any, has a basic side chain?arrow_forward
- Chemistry: An Atoms First ApproachChemistryISBN:9781305079243Author:Steven S. Zumdahl, Susan A. ZumdahlPublisher:Cengage LearningChemistryChemistryISBN:9781305957404Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCostePublisher:Cengage Learning
- Chemistry: The Molecular ScienceChemistryISBN:9781285199047Author:John W. Moore, Conrad L. StanitskiPublisher:Cengage LearningIntroduction to General, Organic and BiochemistryChemistryISBN:9781285869759Author:Frederick A. Bettelheim, William H. Brown, Mary K. Campbell, Shawn O. Farrell, Omar TorresPublisher:Cengage LearningGeneral, Organic, and Biological ChemistryChemistryISBN:9781285853918Author:H. Stephen StokerPublisher:Cengage Learning