(a)
Interpretation: The lactol formed from intramolecular cyclization of given hydroxyl aldehyde is to be predicted.
Concept introduction:
Cyclic hemiacetals containing five or six-membered rings are generally stable and can be isolated.
(b)
Interpretation: The lactol formed from intramolecular cyclization of given hydroxyl aldehyde is to be predicted.
Concept introduction: Aldehydes or ketones on reaction with one equivalent of alcohol form hemiacetal and on reaction with two equivalents of alcohol it forms acetals. This is nucleophilic addition reaction. These reactions takes place in presence of acids, commonly
Cyclic hemiacetals containing five or six-membered rings are generally stable and can be isolated.
Trending nowThis is a popular solution!
Chapter 21 Solutions
ORGANIC CHEMISTRY
- Draw a stepwise mechanism for the following reaction that forms ether D. D can be converted to the antidepressant fluoxetine (trade name Prozac) in a single step.arrow_forwardWhich of the following are a. hemiacetals? b. acetals? c. hydrates?arrow_forwardGive the IUPAC name for each aldehyde.arrow_forward
- Draw a stepwise mechanism for the following reaction that forms ether D. D can be converted to the antidepressant uoxetine (trade name Prozac) in a single step.arrow_forwardDraw a stepwise mechanism for the formation of A from an alcohol and acid chloride. A was converted in one step to blattellaquinone, the sex pheromone of the female German cockroach Blattella germanica.arrow_forwardDraw a stepwise mechanism for the attached reaction that forms ether D. D can be converted to the antidepressant fluoxetine (trade name Prozac) in a single steparrow_forward
- Draw the stepwise mechanism for the following reaction. 1. LDA, THF 2. Brarrow_forward2. How many different ß-hydroxyaldehydes and ß-hydroxyketones, including constitutional isomers and stereoisomers, are formed upon treatment of a mixture of acetone and benzaldehyde with base? a. b. 2 c. 3 d. 4arrow_forwardSafrole is a naturally occurring acetal isolated from sassafras plants. Once used as a common food additive in root beer and other beverages, it is now banned because it is carcinogenic. What compounds are formed when safrole is hydrolyzed with aqueous acid? safrolearrow_forward
- Chemistry for Today: General, Organic, and Bioche...ChemistryISBN:9781305960060Author:Spencer L. Seager, Michael R. Slabaugh, Maren S. HansenPublisher:Cengage Learning