Essentials of Genetics (9th Edition) - Standalone book
9th Edition
ISBN: 9780134047799
Author: William S. Klug, Michael R. Cummings, Charlotte A. Spencer, Michael A. Palladino
Publisher: PEARSON
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Chapter 22, Problem 15PDQ
One of the first Mendelian traits identified in humans was a dominant condition known as brachydactyly. This gene causes an abnormal shortening of the fingers or toes (or both). At the time, some researchers thought that the dominant trait would spread until 75 percent of the population would be affected (because the
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Consider Mendelian traits versus polygenic traits. What impact do modifications, such as those offered by CRISPR and genetic testing, have on the generational lineage of these traits?Are some traits (e.g., susceptibility to Sickle Cell Anemia) worth removing from our genome? Support your position.
Which of the following is not true of the sickle-cell allele?
a)it became an important genetic factor after slash-and-burn agriculture was introduced
b)it became an important genetic factor after fields were cleared that put humans near mosquitos
c)it became an important genetic factor approximately 2000 years ago
d)it provides a reproductive advantage to heterozygotes
e)only homozygous normals will survive thanks to this trait
What do you notice is similar about the distribution of the HERC2 variant for blue eyes and the F374 allele for lighter skin pigmentation? Based on what you know about skin color and human variation, what evolutionary circumstances might have caused this distribution of the blue-eye variant?
Chapter 22 Solutions
Essentials of Genetics (9th Edition) - Standalone book
Ch. 22 - CASE STUDY |An unexpected outcome A newborn...Ch. 22 - CASE STUDY |Anunexpected outcome A newborn...Ch. 22 - CASE STUDY|An unexpected outcome A newborn...Ch. 22 - HOW DO WE KNOW? Population geneticists study...Ch. 22 - Review the Chapter Concepts on page 441. All these...Ch. 22 -
3. Price et al. (1999. J. Bacteriol. 181:...Ch. 22 -
4. The genetic difference between two Drosophila...Ch. 22 - The use of nucleotide sequence data to measure...Ch. 22 - Calculate the frequencies of the AA, Aa, and aa...Ch. 22 - Prob. 7PDQ
Ch. 22 -
8. What must be assumed in order to validate the...Ch. 22 - In a population where only the total number of...Ch. 22 -
10. If 4 percent of a population in equilibrium...Ch. 22 -
11. Consider a population in which the frequency...Ch. 22 - If the initial allele frequencies are p = 0.5 and...Ch. 22 -
13. Under what circumstances might a lethal...Ch. 22 - Assume that a recessive autosomal disorder occurs...Ch. 22 -
15. One of the first Mendelian traits identified...Ch. 22 -
16. Describe how populations with substantial...Ch. 22 - Achondroplasia is a dominant trait that causes a...Ch. 22 -
18. A recent study examining the mutation rates...Ch. 22 - A form of dwarfism known as Ellis–van Creveld...Ch. 22 -
20. List the barriers that prevent interbreeding...Ch. 22 - What are the two groups of reproductive isolating...Ch. 22 - Prob. 22PDQCh. 22 -
23. In a recent study of cichlid fish inhabiting...Ch. 22 - What genetic changes take place during speciation?Ch. 22 - Some critics have warned that the use of gene...Ch. 22 - Comparisons of Neanderthal mitochondrial DNA with...
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- Evolution takes place through a combination of mechanisms at the level of populations. This process consists of a change in allele frequencies in a population over time. Consider the following scenario: You are observing a population of wild mice that has a dominant allele which produces white-colored fur, while the homozygous recessive alleles result in dark brown fur. Genetic studies have indicated that this gene for fur color follows Mendelian inheritance. Originally, the mice population was comprised of over 80% of white mice in a dark forest environment. As the local fox population increased, you noticed that there were fewer white mice and more brown-colored mice. By the end of your observation period of six months, you notice that brown-colored mice now make up over 60% of the total mice population. Based on this scenario, explain what force of evolution is at workarrow_forwardEvolution takes place through a combination of mechanisms at the level of populations. This process consists of a change in allele frequencies in a population over time. Consider the following scenario: You are observing a population of wild mice that has a dominant allele which produces white-colored fur, while the homozygous recessive alleles result in dark brown fur. Genetic studies have indicated that this gene for fur color follows Mendelian inheritance. Originally, the mice population was comprised of over 80% of white mice in a dark forest environment. As the local fox population increased, you noticed that there were fewer white mice and more brown-colored mice. By the end of your observation period of six months, you notice that brown-colored mice now make up over 60% of the total mice population. 1. Based on this scenario, explain what force of evolution is at work. 2. Are you observing microevolution or macroevolution? Explain your answer.arrow_forwardWhen Gregor Mendel first proposed his theories on genetics, they were not recognized. This was because: A. Charles Darwin didn't agree with Gregor Mendel's theories. B. The current theory was that traits from parents blended together in their offspring. C. Gregor Mendel proposed that individuals could change their physical traits during their lifetime and pass those new traits on to their offspring. D. Scientists believed there were 5 nucleotide bases, not 4 nucleotide bases.arrow_forward
- Tay-Sachs disease is a recessive genetic disease. Individuals with this disease rarely survive past the age of four. In the general population, approximately 1 person in 300 carries the allele for this disease. However, in some populations, including the Irish Americans, the Ashkenazi Jews and the Cajuns from Louisiana, the proportion of Tay-Sachs carriers is much higher (1 in 27 to 1 in 50) than in other populations. Which evolutionary scenario can be predicted to produce a high frequency of Tay-Sachs disease in these populations? Select one: a. All three populations descend from a small number of settlers b. The Tay-Sachs allele is advantageous at the heterozygous state c. These populations experienced disruptive selection d. These populations experienced stabilizing selection e. These populations have higher than average mutation ratesarrow_forwardYou are examining a population of snakes in which 20% of the individuals exhibit the recessive phenotype for albinism. If albinism is exhibited only by the genotype aa, how many snakes out of a population of 100 would you expect to CARRY the albinism allele (so be Aa), but be normal color?arrow_forwardRecently, scientists have identified a mutation that is found at high frequency in Finnish populations, located in northern Europe where the winter is very cold. This mutation is believed to be a “cold sensitive” allele that warns people of extreme cold temperatures. Could this allele have undergone a “selective sweep”, if it had suddenly appeared in this northern population of humans? How would such a selective sweep be detected with genome data?arrow_forward
- Gregor Johann Mendel carried out experiments with pea plants that demonstrated how certain physical traits were passed down from one generation to the next in a predictable pattern. He introduced the concepts of dominant and recessive traits and established fundamental laws of inheritance for what is known as Mendelian Genetics. A trait can be inherited when each parent passes down one copy of a gene. Different versions of the same gene are known as alleles. Both gene copies are an organism’s genotype, and the physical expression of those genes is a phenotype. 1. Explain one of the three laws of inheritance proposed by Mendelian genetics. Mendelian inheritance can be visualized using Punnett squares. The first row and column represent the parental alleles, while the squares predict the possible combination of alleles of the resulting offspring. Dominant alleles are indicated by uppercase letters while recessive alleles are indicated by lowercase letters. The combination of alleles in…arrow_forwardIf, within specific regional populations over two thousand years ago, sickle-cell anemia killed those individuals born with it before they could reproduce to pass it on to offspring, how did it persist in these populations? Group of answer choices A-Because of late-onset of the disease. B-Because it is cause by a virus and it spreads faster than people died. C-Because of the basic principles of mendelian inheritance that result in some heterozygote "carrier" combinations. D-Because malaria made it possible to survive sickle cell anemia since the parasite would carry oxygen on the blood cells with the mutated hemoglobin. E-It does not persist. Natural selection removes the allele because people die from both malaria and sickle-cell anemia.arrow_forwardIf the frequency of those exhibiting a monogenic autosomal recessive phenotype caused by a rare clinically relevant allele is 1/8500 in a given population, what is the carrier frequency? Please give your answer as a percentage to 3 decimal places, do not include the % symbol. ANSWER: In a population where the frequency of those exhibiting a monogenic autosomal recessive phenotype caused by only one known mutation is 1/8500 the carrier frequency is a percent.arrow_forward
- Sometimes, genetic make-ups do not show up as traits. Let us assume Jane has beautiful brown eyes. Her dad has beautiful blue eyes (pure-bred blue eyes, to say, he has only blue eye genes), while her mom has beautiful brown eyes (pure-bred brown eyes, to say, she has only brown eye genes). Then Jane must be a half brown eye and a half-blue eye, but she has only brown eyes. Why and how this could happen?arrow_forwardIn genetics, the dash symbol (–) is a “wild card” that stands for either the dominant allele or the recessive allele; for example, A– means the individual has either the genotype AA or Aa. Two genes that undergo independent assortment affect coat color in Duroc pigs. Each gene has two alleles, one of which is dominant for coat color. Genotypes of the form A– B– are red, those of the form A– bb and aa B– are sandy, and genotype aa bb is white. What ratio of red:sandy:white is expected from the cross Aa Bb x Aa Bb?arrow_forwardYou are studying a population of penguins in Antarctica. Your DNA analysis of this population reveals that for the feather color pattern gene, 35 individuals are homozygous dominant, 35 individuals are heterozygous, and 30 individuals are homozygous recessive. After observing this population for several years, you repeat your DNA study and find that the current generation of penguins has 15 individuals that are homozygous dominant, 10 individuals that are heterozygous, and 75 individuals that are homozygous recessive. Which of the following hypotheses for this data would be supported by this data based on your understanding of Hardy-Weinberg equilibrium? This population of penguins is maintaining Hardy-Weinberg equilibrium due to its large population size. The penguins are randomly choosing mates, which has led to Hardy-Weinberg equilibrium. The penguins are very isolated, which is preventing gene flow from affecting Hardy-Weinberg equilibrium. The recessive phenotype in…arrow_forward
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How to solve genetics probability problems; Author: Shomu's Biology;https://www.youtube.com/watch?v=R0yjfb1ooUs;License: Standard YouTube License, CC-BY
Beyond Mendelian Genetics: Complex Patterns of Inheritance; Author: Professor Dave Explains;https://www.youtube.com/watch?v=-EmvmBuK-B8;License: Standard YouTube License, CC-BY