(a)
Interpretation:
The reason for accumulation of phytanic acid should be determined.
Concept introduction:
The refsum disease is an autosomal recessive disease. It is caused due to the accumulation of phytanic acid in the body, which can lead to neurodegenerative disease. This disease occurs at the onset of adolescence and is diagnosed by the high levels of phytanic acid. This fatty acid is consumed by humans in regular diets.
(b)
Interpretation:
The enzyme activity that can be invented to prevent it from accumulation.
Concept introduction:
The refsum disease is an autosomal recessive disease. It is caused due to the accumulation of phytanic acid in the body, which can lead to neurodegenerative disease. This disease occurs at the onset of adolescence and is diagnosed by the high levels of phytanic acid. This fatty acid is consumed by the humans in the regular diets.
Want to see the full answer?
Check out a sample textbook solutionChapter 22 Solutions
Biochemistry
- Accepting. Which of the following compounds readily accepts amino groups from amino acids? a. Glutamine b. Isocitrate c. Malate d. a-Ketoglutarate-Ketoglutaratearrow_forwardCrohn’s disease. Omega-3 fatty acids have been tested asa means to prevent relapse of Crohn’s disease. Two large,randomized, placebo-controlled studies have shown nosuch benefit from omega-3 fatty acids. Suppose you areasked to design an experiment to further study this claim.Imagine that you have collected data on Crohn’s relapsesin subjects who have used these omega-3 fatty acids and similar subjects who have not used them and that you canmeasure incidences of relapse for these subjects. Statethe null and alternative hypotheses you would use in yourstudy.arrow_forwardNeed help, please. Not too sure why my answer is incorrect. Please show all steps/work.arrow_forward
- BIOCHEMISTRY. Could glycerol be used to regenerate the OAA for maintenance of TCA cycle activity? Yes or No? Explain.arrow_forwardBIOCHEMISTRY DRAWING. pls accept question only if 100% confident please and thank you. Enalapril is inactive until acted upon by an esterase. Draw the structure of the resulting bioactive derivative. Hintarrow_forwardplease explain. I will rate your response based on the accuracy of your answers. Two right answers get a thumbs up rating! Thank you.arrow_forward
- Need help, please.arrow_forwardI. Active site analysis. Below is a diagram of a putative active site for Monoamine oxidase. As we learned, the purpose of tertiary structure is to form a scaffold so you can orient just a few amino acids in the right orientation to promote binding and/or catalysis. The position where this occurs is the active site. The amino acid architecture of an active site is designed to bind substrates. Amino acid side chains are capable of hydrogen bonding, ionic and hydrophobic interactions. Fill in each amino acid that you think is suitable for interacting with the part of the substrate it is closest to. Assume the pH will be at 7.0 a.a.#1 a.a.#2 a.a.#6 HO Lond NH₂ НО a.a.#5 OH a.a.#3 a.a.#4arrow_forwardIs this correct? Thanks.arrow_forward
- BiochemistryBiochemistryISBN:9781319114671Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.Publisher:W. H. FreemanLehninger Principles of BiochemistryBiochemistryISBN:9781464126116Author:David L. Nelson, Michael M. CoxPublisher:W. H. FreemanFundamentals of Biochemistry: Life at the Molecul...BiochemistryISBN:9781118918401Author:Donald Voet, Judith G. Voet, Charlotte W. PrattPublisher:WILEY
- BiochemistryBiochemistryISBN:9781305961135Author:Mary K. Campbell, Shawn O. Farrell, Owen M. McDougalPublisher:Cengage LearningBiochemistryBiochemistryISBN:9781305577206Author:Reginald H. Garrett, Charles M. GrishamPublisher:Cengage LearningFundamentals of General, Organic, and Biological ...BiochemistryISBN:9780134015187Author:John E. McMurry, David S. Ballantine, Carl A. Hoeger, Virginia E. PetersonPublisher:PEARSON