Genetics: Analysis and Principles
6th Edition
ISBN: 9781259616020
Author: Robert J. Brooker Professor Dr.
Publisher: McGraw-Hill Education
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Textbook Question
Chapter 23, Problem 7EQ
A researcher is interested in a gene found on human chromosome 21. Describe the expected results of a FISH experiment using a probe that is complementary to this gene. How many spots would you see if the probe was used on a sample from an individual with 46 chromosomes versus an individual with Down syndrome?
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The figure shown describes the technique of FISH. Why is it necessaryto fix the cells (and the chromosomes inside of them) to the slides?What does it mean to fix them? Why is it necessary to denature thechromosomal DNA?
in the human genome project, scientists have identified the sequence of the base pairs of the human chromosome, and are working to determine what?
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Why do we only need 23 chromosomes for DNA sequencing, when the two homologous pairs do not have the exact same nucleotide sequences? Why don't we use all 46 chromosomes?
Chapter 23 Solutions
Genetics: Analysis and Principles
Ch. 23.1 - Prob. 1COMQCh. 23.2 - Prob. 1COMQCh. 23.3 - A molecular marker is a _____ found at a specific...Ch. 23.3 - 2. Which of the following is an example of a...Ch. 23.3 - To map the distance between molecular markers via...Ch. 23.4 - 1. What is a contig?
a. A fragment of DNA that...Ch. 23.4 - A vector that can carry a large fragment of...Ch. 23.4 - 3. Chromosomal walking is a method of _____ in...Ch. 23.5 - Prob. 1COMQCh. 23.5 - Prob. 2COMQ
Ch. 23.5 - 3. A prokaryotic genome is about 4 million bp in...Ch. 23.6 - Metagenomics is aimed at a. determining the...Ch. 23 - 1. A person with a rare genetic disease has a...Ch. 23 - For each of the following, decide if it could be...Ch. 23 - Which of the following statements about molecular...Ch. 23 - 1. Is each of the following a method used in...Ch. 23 - Prob. 2EQCh. 23 - Prob. 3EQCh. 23 - The cells from a persons malignant tumor were...Ch. 23 - 5. Figure 23.2 describes the technique of FISH....Ch. 23 - Explain how DNA probes with different fluorescence...Ch. 23 - 7. A researcher is interested in a gene found on...Ch. 23 - Prob. 8EQCh. 23 - Prob. 9EQCh. 23 - Prob. 10EQCh. 23 - Prob. 11EQCh. 23 - Prob. 12EQCh. 23 - In the Human Genome Project, researchers have...Ch. 23 - 14. Take a look at question 3 in More Genetic...Ch. 23 - 15. Place the following stages of a physical...Ch. 23 - 16. What is an STS? How are STSs generated...Ch. 23 - 17. Four cosmid clones, which we will call cosmids...Ch. 23 - A human gene, which we will call geneX, is located...Ch. 23 - 19. Describe how you would clone a gene by...Ch. 23 - 20. A bacterium has a genome size of 4.4 Mb. If a...Ch. 23 - 21. Discuss the advantages of next-generation...Ch. 23 - Prob. 22EQCh. 23 - Prob. 23EQCh. 23 - What is a molecular marker? Give two examples....Ch. 23 - Which goals of the Human Genome Project do you...
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Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.Similar questions
- Using a laser beam, you isolated several R bands from human chromosomes. Answer the following questions What kinds of genes are present in R bands? Which isochors do you expect to be present in the R band? What class of interspersed repeats will be present in R bands? What class of tandem repeats do you expect to find in RG bands? Would you expect to find telomere sequences in some R bands?arrow_forwardWhat percentage of the DNA in the genome actually corresponds to genes? How much is actually protein-coding exons? What makes up the rest?arrow_forwardCan you cite a situation in which it shows how important two strands on the same chromosome have identical genetic information?arrow_forward
- At the end of an experiment, you extract DNA from ten yeast colonies. You divide the DNA from each colony into two tubes, and send all twenty samples for sequencing. How many experimental replicates do you have?arrow_forwardIf you had the ability to do gene editing with ONE gene for the betterment of human kind, which one would you choose, and why? Assume you could either change an abnormal allele associated with a disease, such as the cystin gene associated with Cystic Fibrosis to its normal wild type, or add a pre-existing human allele to a genome.arrow_forwardDNA fingerprinting does not study the whole chromosome. Explain.arrow_forward
- What would happen if a chromosome didn't have telomeres, or telomerase was faulty?arrow_forwardCompare and contrast transposons and genomic islands.arrow_forwardBefore the advent of recombinant DNA technology, why was it so diffcult for geneticists to map human genes using pedigrees? How did recombinant DNA technology help move things forward?arrow_forward
- IF YOU WERE TO CREATE RECOMBINANT DNA OF YOUR OWN, WHAT GENE COMBINATION WOULD YOU LIKE TO HAVE AND WHY?arrow_forwardWhat is a recombinant DNA? Select one: a. During meiosis, sister chromatids cross over to produce daughter cells with recombinant DNA. b. Any genome that is non-parental is called a recombinant DNA. c. New DNA sequences are inserted into a genome to produce recombinant DNA. d. Bacterial plasmid with sticky ends are referred to as the recombinant DNA.arrow_forwardHypothetically, a cell has DNA that weighs 10 picograms. This cell goes through S phase and is about to undergo mitosis. How much does the DNA of this cell weight now? How much would the DNA of the two cells produced at the end of mitosis weigh? Explain your reasoning.arrow_forward
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