![BIOLOGY-TEXT](https://compass-isbn-assets.s3.amazonaws.com/isbn_cover_images/9781260169621/9781260169621_smallCoverImage.jpg)
BIOLOGY-TEXT
5th Edition
ISBN: 9781260169621
Author: BROOKER
Publisher: MCG
expand_more
expand_more
format_list_bulleted
Question
Chapter 24.4, Problem 2CC
Summary Introduction
To predict: The effect of the expression of Drosophila’s eyeless gene on the tip of the mouse’s tail.
Introduction: The Pax6 (paired box) is a transcription factor protein-encoding gene that controls the regulation of expression of many different genes. This gene is known to coordinate the development of the eye in rats and humans. Any mutation in the gene can cause underdevelopment leading to small eyes.
Expert Solution & Answer
![Check Mark](/static/check-mark.png)
Want to see the full answer?
Check out a sample textbook solution![Blurred answer](/static/blurred-answer.jpg)
Students have asked these similar questions
Dominguez et al. (2004) suggest that by studying genes that determine growth and tissue specification in the eye of Drosophila, much can be learned about human eye development. (a) What evidence suggests that genetic eye determinants in Drosophila are also found in humans? Include a discussion of orthologous genes in your answer. (b) What evidence indicates that the eyeless gene is part of a developmental network?
Dominguez et al. (2004) suggest that by studying genes that determine growth and tissue specification in the eye of Drosophila, much can be learned about human eye development. (a) What evidence suggests that genetic eye determinants in Drosophila are also found in humans? Include a discussion of orthologous genes in your answer. (b) What evidence indicates that the eyeless gene is part of a developmental network? (c) Are genetic networks likely to specify developmental processes in general? Explain fully and provide an example.
Compare and contrast the experimental advantages and disadvantages of Drosophila, C. elegans, mammals, and Arabidopsis.
Chapter 24 Solutions
BIOLOGY-TEXT
Ch. 24.1 - Can you think of another example of two different...Ch. 24.1 - Prob. 1CSCh. 24.1 - Is temporal isolation an example of a prezygotic...Ch. 24.1 - Prob. 3CCCh. 24.2 - Prob. 1CSCh. 24.2 - Prob. 1EQCh. 24.2 - Prob. 2EQCh. 24.2 - Prob. 3EQCh. 24.2 - Prob. 1CCCh. 24.2 - Prob. 2CC
Ch. 24.4 - Evo-Devo: Evolutionary Developmental Biology...Ch. 24.4 - Prob. 1CSCh. 24.4 - Prob. 2CCCh. 24 - Macroevolution refers to evolutionary changes that...Ch. 24 - Prob. 2TYCh. 24 - Prob. 3TYCh. 24 - Prob. 4TYCh. 24 - Prob. 5TYCh. 24 - Prob. 6TYCh. 24 - Prob. 7TYCh. 24 - Prob. 8TYCh. 24 - Prob. 9TYCh. 24 - Prob. 10TYCh. 24 - What is the key difference between prezygotic and...Ch. 24 - What are the key differences between gradualism...Ch. 24 - Prob. 3CQCh. 24 - Prob. 1COQCh. 24 - Discuss the type of speciation (allopatric or...
Knowledge Booster
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.Similar questions
- CONNECT Why is an understanding of gene regulation in eukaryotes crucial to an understanding of developmental processes? Explain your answerarrow_forwardprovide one example from the Drosophila AP toolkit for "Toolkit genes can be classified according to the phenotypes caused by their mutation. Similar mutant phenotypes often reflect genes that function in a single developmental pathway. Distinct pathways exist for the generation of body axes, for example, and for the formation and identity of fields."arrow_forwardIt seems that developmental genetics boils down to a complex network of gene regulation. Try to draw a structure of this network for Drosophila. How many genes do you think are necessary to complete the developmental network for the fruit fly? How many genes do you think are needed for a network to specify one segment? Do you think it is more difficult to identify genes that are involved in the beginning, middle, or end of this network? Suppose you were trying to identify all of the genes needed for development in a chicken. Knowing what you know about Drosophila development, would you first try to identify genes necessary for early development, or would you begin by identifying genes involved in cell differentiation?arrow_forward
- Explain hoxA3 and HoxD3 genes are nearly equivalent yet they play distinct roles in the development of mouse.arrow_forwardDiscuss the role of homeotic genes in development. Explain what happens to the phenotype of a fruit fly when a gain-of-function mutation in a homeotic gene causes the protein to be expressed in an abnormal region of the embryo. What are the consequences of a loss-of-function mutation in such a gene?arrow_forwardDiscuss the role of par genes in generating anterior/posterior polarity in the C. elegans embryo.arrow_forward
- Describe the role of coordinate genes, gap genes, pair rule genes, segment polarity genes, and homeotic genes in Drosophila development.arrow_forwardYou have identified a Drosophila gene that is expressed exclusively in the odd-numbered "stripes" in the cellular blastoderm. Assuming that this gene is not redundant, what would be the most likely phenotype cause by a loss-of-function mutation in this gene? an embryo missing odd numbered segments an adult fly with a second pair of wings instead of halteres an embryo with two anterior ends an embryo missing even-numbered segments an embryo missing larval segments 3-10arrow_forwardBriefly explain the transcriptional regulation of mammalian gene expression? Please explain at your own words.arrow_forward
- What is positional information? Discuss three different ways that cells obtain positional information. Which of these three ways do you think is the most important for the formation of a segmented body pattern in Drosophila?arrow_forwardYou are studying Hox genes in crane flies (Leptotarsus testaceus). The cranefly genome is sequenced, and in craneflies. Using your understanding of Hox genes, design an experiment testing where the homolog of the EVE gene is expressed in cranefly embryos. you have access to this sequence. You are interested in studying the EVE genearrow_forwardAnimal Models: The Search for Behavior Genes You are a researcher studying an autosomal dominant neurodegenerative disorder. You have cloned the gene underlying the disorder and have found that it encodes an enzyme that is overexpressed in the neurons of individuals who have the disorder. To better understand how this enzyme causes neurodegeneration in humans, you make a strain of transgenic Drosophila whose nerve cells overexpress the enzyme. a. How might you use these transgenic flies to try to gain insight into the disease or identify drugs that might be useful in the treatment of the disease? b. Can you think of any potential limitations of this approach?arrow_forward
arrow_back_ios
SEE MORE QUESTIONS
arrow_forward_ios
Recommended textbooks for you
- Biology (MindTap Course List)BiologyISBN:9781337392938Author:Eldra Solomon, Charles Martin, Diana W. Martin, Linda R. BergPublisher:Cengage LearningBiology: The Dynamic Science (MindTap Course List)BiologyISBN:9781305389892Author:Peter J. Russell, Paul E. Hertz, Beverly McMillanPublisher:Cengage LearningHuman Heredity: Principles and Issues (MindTap Co...BiologyISBN:9781305251052Author:Michael CummingsPublisher:Cengage Learning
![Text book image](https://www.bartleby.com/isbn_cover_images/9781337392938/9781337392938_smallCoverImage.gif)
Biology (MindTap Course List)
Biology
ISBN:9781337392938
Author:Eldra Solomon, Charles Martin, Diana W. Martin, Linda R. Berg
Publisher:Cengage Learning
![Text book image](https://www.bartleby.com/isbn_cover_images/9781305389892/9781305389892_smallCoverImage.gif)
Biology: The Dynamic Science (MindTap Course List)
Biology
ISBN:9781305389892
Author:Peter J. Russell, Paul E. Hertz, Beverly McMillan
Publisher:Cengage Learning
![Text book image](https://www.bartleby.com/isbn_cover_images/9781305251052/9781305251052_smallCoverImage.gif)
Human Heredity: Principles and Issues (MindTap Co...
Biology
ISBN:9781305251052
Author:Michael Cummings
Publisher:Cengage Learning
Embryology | Fertilization, Cleavage, Blastulation; Author: Ninja Nerd;https://www.youtube.com/watch?v=8-KF0rnhKTU;License: Standard YouTube License, CC-BY