Fundamentals of Biochemistry: Life at the Molecular Level
Fundamentals of Biochemistry: Life at the Molecular Level
5th Edition
ISBN: 9781118918401
Author: Donald Voet, Judith G. Voet, Charlotte W. Pratt
Publisher: WILEY
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Chapter 25, Problem 23E
Summary Introduction

To explain: The reason for the existence of hot spots in certain sites of E.coli chromosomes.

Introduction: Point mutation is the mutation that occurs at any one nucleobase present in the DNA strand. Certain bases in the DNA spontaneously mutate to form modified bases. One such modification is the spontaneous deamination of 5-methylcytosine to thymine base, which is the major cause of the observation of hot spots in E.coli chromosomes.

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Mitochondrial mutations; Author: Useful Genetics;https://www.youtube.com/watch?v=GvgXe-3RJeU;License: CC-BY