Chapter 25, Problem 9E

Summary Introduction

To explain: The reason why the association of RNA primer with clamp maximizes the efficiency of DNA replication rather than the association of RNA primer directly to DNA polymerase.

Introduction: DNA replication is a process that takes place in every biological cell involving the coping and producing two identical copies of a cell from a parent DNA molecule. There are different types of enzymes and factors whose co-participation mediate and help the other enzymes to replicate DNA efficiently. DNA clamp is a protein complex or a fold that helps the attachment of DNA polymerase enzyme to the template strand and prevents the enzyme fall-off from the strand.