Brock Biology Of Microorganisms - Package
Brock Biology Of Microorganisms - Package
14th Edition
ISBN: 9780134462660
Author: MADIGAN
Publisher: PEARSON
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Chapter 26.1, Problem 2MQ
Summary Introduction

Pathogen associated molecular patterns (PAMPs) are characterized by structural components of pathogenic organisms. Generally, they are composed of macromolecules such as nucleic acids, proteins, polysaccharides, and lipids. For instance, a lipopolysaccharide (LPS), situated in the gram-negative bacteria cell walls is an example of a PAMP. A set of membrane bound proteins of the host that are soluble and may interact with PAMPs are considered as pattern recognition receptors (PRRs). TLR-4 (a PRR) is an important constituent of innate immune mechanism, which acts towards LPS of bacteria.

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