Concept explainers
Interpretation:
A mechanism for the first step in the biological degradation of lysine, the reductive
Concept introduction:
The following steps involved in the reductive amination of lysine with α- ketoglutarate to yield saccharopine using nicotinamide adenine dinucleotide phosphate (NADPH) as the reducing agent. i) The attack of the amino acid N on the carbonyl group of α- ketoglutarate ii) A proton tranfer iii) Elimination of water iv) Reduction by NADPH.
To propose:
A mechanism for the first step in the biological degradation of lysine, the reductive amination with α- ketoglutarate to yield saccharopine using nicotinamide adenine dinucleotide phosphate (NADPH) as the reducing agent.
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Organic Chemistry
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