Genetics: Analysis and Principles
6th Edition
ISBN: 9781259616020
Author: Robert J. Brooker Professor Dr.
Publisher: McGraw-Hill Education
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Chapter 27, Problem 14EQ
Summary Introduction
To review:
Whether a 60% match between the DNA of the father and the daughter is too high, and if only a 50% match should be expected.
Introduction:
Professor Sir Alec Jeffrey discovered DNA fingerprinting based on the understanding that the differences in human DNA (deoxyribonucleic acid) can be detected on the basis of minisatellites. The pattern of DNA fragments is unique for every individual, and it forms the DNA fingerprint of that individual.
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Chapter 27 Solutions
Genetics: Analysis and Principles
Ch. 27.1 - A gene pool is a. all of the genes in a single...Ch. 27.1 - 2. In natural populations, most genes...Ch. 27.1 - A gene exists in two alleles designatedDandd. If...Ch. 27.1 - Prob. 4COMQCh. 27.2 - Which of the following is a factor that, by...Ch. 27.3 - 1. Darwinian fitness is a measure...Ch. 27.3 - 2. Within a particular population, darkly colored...Ch. 27.3 - 3. A population occupies heterogeneous...Ch. 27.3 - Prob. 4COMQCh. 27.4 - 1. Genetic drift is
a. a change in allele...
Ch. 27.4 - 2. Which of the following influences on genetic...Ch. 27.5 - Gene flow depends on a. migration. b. the ability...Ch. 27.6 - 1. Inbreeding is sexual reproduction between...Ch. 27.7 - The mutation rate is a. the likelihood that a new...Ch. 27.7 - 2. The transfer of an antibiotic resistance gene...Ch. 27.7 - Prob. 3COMQCh. 27 - 1. What is the gene pool? How is a gene pool...Ch. 27 - Prob. 2CONQCh. 27 - Prob. 3CONQCh. 27 - Prob. 4CONQCh. 27 - The termpolymorphismcan refer to both genes and...Ch. 27 - Prob. 6CONQCh. 27 - For a gene existing in two alleles, what are the...Ch. 27 - 8. In a population, the frequencies of two...Ch. 27 - The ability to roll your tongue is inherited as a...Ch. 27 - What evolutionary factors can cause allele...Ch. 27 - What is the difference between a neutral and an...Ch. 27 - Prob. 12CONQCh. 27 - Prob. 13CONQCh. 27 - Describe the similarities and differences among...Ch. 27 - 15. Is each of the following examples due to...Ch. 27 - Prob. 16CONQCh. 27 - Prob. 17CONQCh. 27 - 18. A group of four birds flies to a new location...Ch. 27 - 19. Describe what happens to allele frequencies as...Ch. 27 - With regard to genetic drift, are the following...Ch. 27 - When two populations frequently intermix due to...Ch. 27 - Two populations of antelope are separated by a...Ch. 27 - Prob. 23CONQCh. 27 - 24. Using the pedigree shown here, answer the...Ch. 27 - A family pedigree is shown here. A. What is the...Ch. 27 - 26. A family pedigree is shown here.
A. What is...Ch. 27 - Prob. 27CONQCh. 27 - Prob. 28CONQCh. 27 - 1. You will need to be familiar with the...Ch. 27 - You will need to refer to question 2 in More...Ch. 27 - Prob. 3EQCh. 27 - Prob. 4EQCh. 27 - You will need to refer to question 2 in More...Ch. 27 - Prob. 6EQCh. 27 - Prob. 7EQCh. 27 - In the Grants study of the medium ground finch, do...Ch. 27 - 9. A recessive lethal allele has achieved a...Ch. 27 - Among a large population of 2 million gray...Ch. 27 - In a donor population, the allele frequencies for...Ch. 27 - Prob. 12EQCh. 27 - Prob. 13EQCh. 27 - Prob. 14EQCh. 27 - 15. What would you expect to be the minimum...Ch. 27 - Discuss examples of positive and negative...Ch. 27 - Discuss the role of mutation in the origin of...Ch. 27 - Prob. 3QSDC
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- What is DNA fingerprinting? What types of sequences are examined in DNA fingerprinting?arrow_forwardWhat is DNA fingerprinting? Mention its applications?arrow_forwardDo you think an unintended consequence of genetic testing could be that people would be less liable to seek medical care out of fear that they could later be denied life or health insurance? What laws should be used to govern the use of genetic data of this type?arrow_forward
- Which of the following pairs of sequences would be considered different alleles in DNA profiling? a) ATGAATTCGG; ATGAAATCGG b) ATGAATTCGG; TACTTACTTACT c) GAAGAAGAA; GAAGAAGAAGAA d) AATAATAATAAT; AATTAATTAATTarrow_forwardIn 1967, a couple accused a hospital of switching their baby with another. DNA interpretation did not exist at this time so the hospital traced the blood types of the family in order to determine if a mistake was made. The mother had Type A blood, the father had Type AB blood, and the baby had Type O blood. Use the Punnett square to defend your answer to the following question: Did the hospital make a mistake and switch the baby? ____________arrow_forwardHow to find any evidence of cantamination or degradation of DNA in the DNA profiles you examined? how important is the detabase that is used to determine allele frequencies in DNA profiling casesarrow_forward
- What is the accuracy of DNA fingerprinting and How conclusive is the evidence of DNA fingerprinting?arrow_forwardPedigree Analysis Is a Basic Method in Human Genetics Using the pedigree provided, answer the following questions. a. Is the proband male or female? b. Is the grandfather of the proband affected? c. How many siblings does the proband have, and where is he or she in the birth order?arrow_forwardPedigree Analysis Is a Basic Method in Human Genetic: What does OMIM stand for? What kinds of information are in this database?arrow_forward
- Pedigree analysis is a fundamental tool for investigating whether or not a trait is following a Mendelian pattern of inheritance. It can also be used to help identify individuals within a family who may be at risk for the trait. Adam and Sarah, a young couple of Eastern European Jewish ancestry, went to a genetic counselor because they were planning a family and wanted to know what their chances were for having a child with a genetic condition. The genetic counselor took a detailed family history from both of them and discovered several traits in their respective families. Sarahs maternal family history is suggestive of an autosomal dominant pattern of cancer predisposition to breast and ovarian cancer because of the young ages at which her mother and grandmother were diagnosed with their cancers. If a mutant allele that predisposed to breast and ovarian cancer was inherited in Sarahs family, she, her sister, and any of her own future children could be at risk for inheriting this mutation. The counselor told her that genetic testing is available that may help determine if this mutant allele is present in her family members. Adams paternal family history has a very strong pattern of early onset heart disease. An autosomal dominant condition known as familial hypercholesterolemia may be responsible for the large number of deaths from heart disease. As with hereditary breast and ovarian cancer, genetic testing is available to see if Adam carries the mutant allele. Testing will give the couple more information about the chances that their children could inherit this mutation. Adam had a first cousin who died from Tay-Sachs disease (TSD), a fatal autosomal recessive condition most commonly found in people of Eastern European Jewish descent. Because TSD is a recessively inherited disorder, both of his cousins parents must have been heterozygous carriers of the mutant allele. If that is the case, Adams father could be a carrier as well. If Adams father carries the mutant TSD allele, it is possible that Adam inherited this mutation. Because Sarah is also of Eastern European Jewish ancestry, she could also be a carrier of the gene, even though no one in her family has been affected with TSD. If Adam and Sarah are both carriers, each of their children would have a 25% chance of being afflicted with TSD. A simple blood test performed on both Sarah and Adam could determine whether they are carriers of this mutation. Would you decide to have a child if the test results said that you carry the mutation for breast and ovarian cancer? The heart disease mutation? The TSD mutation? The heart disease and the mutant alleles?arrow_forwardPedigree analysis is a fundamental tool for investigating whether or not a trait is following a Mendelian pattern of inheritance. It can also be used to help identify individuals within a family who may be at risk for the trait. Adam and Sarah, a young couple of Eastern European Jewish ancestry, went to a genetic counselor because they were planning a family and wanted to know what their chances were for having a child with a genetic condition. The genetic counselor took a detailed family history from both of them and discovered several traits in their respective families. Sarahs maternal family history is suggestive of an autosomal dominant pattern of cancer predisposition to breast and ovarian cancer because of the young ages at which her mother and grandmother were diagnosed with their cancers. If a mutant allele that predisposed to breast and ovarian cancer was inherited in Sarahs family, she, her sister, and any of her own future children could be at risk for inheriting this mutation. The counselor told her that genetic testing is available that may help determine if this mutant allele is present in her family members. Adams paternal family history has a very strong pattern of early onset heart disease. An autosomal dominant condition known as familial hypercholesterolemia may be responsible for the large number of deaths from heart disease. As with hereditary breast and ovarian cancer, genetic testing is available to see if Adam carries the mutant allele. Testing will give the couple more information about the chances that their children could inherit this mutation. Adam had a first cousin who died from Tay-Sachs disease (TSD), a fatal autosomal recessive condition most commonly found in people of Eastern European Jewish descent. Because TSD is a recessively inherited disorder, both of his cousins parents must have been heterozygous carriers of the mutant allele. If that is the case, Adams father could be a carrier as well. If Adams father carries the mutant TSD allele, it is possible that Adam inherited this mutation. Because Sarah is also of Eastern European Jewish ancestry, she could also be a carrier of the gene, even though no one in her family has been affected with TSD. If Adam and Sarah are both carriers, each of their children would have a 25% chance of being afflicted with TSD. A simple blood test performed on both Sarah and Adam could determine whether they are carriers of this mutation. Would you want to know the results of the cancer, heart disease, and TSD tests if you were Sarah and Adam? Is it their responsibility as potential parents to gather this type of information before they decide to have a child?arrow_forwardPedigree analysis is a fundamental tool for investigating whether or not a trait is following a Mendelian pattern of inheritance. It can also be used to help identify individuals within a family who may be at risk for the trait. Adam and Sarah, a young couple of Eastern European Jewish ancestry, went to a genetic counselor because they were planning a family and wanted to know what their chances were for having a child with a genetic condition. The genetic counselor took a detailed family history from both of them and discovered several traits in their respective families. Sarahs maternal family history is suggestive of an autosomal dominant pattern of cancer predisposition to breast and ovarian cancer because of the young ages at which her mother and grandmother were diagnosed with their cancers. If a mutant allele that predisposed to breast and ovarian cancer was inherited in Sarahs family, she, her sister, and any of her own future children could be at risk for inheriting this mutation. The counselor told her that genetic testing is available that may help determine if this mutant allele is present in her family members. Adams paternal family history has a very strong pattern of early onset heart disease. An autosomal dominant condition known as familial hypercholesterolemia may be responsible for the large number of deaths from heart disease. As with hereditary breast and ovarian cancer, genetic testing is available to see if Adam carries the mutant allele. Testing will give the couple more information about the chances that their children could inherit this mutation. Adam had a first cousin who died from Tay-Sachs disease (TSD), a fatal autosomal recessive condition most commonly found in people of Eastern European Jewish descent. Because TSD is a recessively inherited disorder, both of his cousins parents must have been heterozygous carriers of the mutant allele. If that is the case, Adams father could be a carrier as well. If Adams father carries the mutant TSD allele, it is possible that Adam inherited this mutation. Because Sarah is also of Eastern European Jewish ancestry, she could also be a carrier of the gene, even though no one in her family has been affected with TSD. If Adam and Sarah are both carriers, each of their children would have a 25% chance of being afflicted with TSD. A simple blood test performed on both Sarah and Adam could determine whether they are carriers of this mutation. If Sarah carries the mutant cancer allele and Adam carries the mutant heart disease allele, what is the chance that they would have a child who is free of both diseases? Are these good odds?arrow_forward
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