Genetics: Analysis and Principles
Genetics: Analysis and Principles
6th Edition
ISBN: 9781259616020
Author: Robert J. Brooker Professor Dr.
Publisher: McGraw-Hill Education
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Chapter 27, Problem 6EQ
Summary Introduction

To analyze:

The allele frequencies at the equilibrium of the given data. The effect on equilibrium when rats are no longer exposed to warfarin.

Introduction:

The relative frequency of a variant of gene or allele being present at a particular locus, which could be expressed as percentage or fraction, is known as allele frequency or gene frequency. Over time, the change in frequencies in a particular population is due to microevolution. The organisms living in the same geographical area with the capability to interbreed is termed as population.

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If gene A/a is not in Hardy-Weinberg equilibrium due to natural selection such that individuals with the genotype AA have a fitness value of 1.0, heterozygotes have only slightly reduced fitness at 0.9, and individuals with the genotype aa have a fitness value of 0.6, what kind of change in allele frequency would you expect to see over time assuming you start with equal frequencies of the 2 alleles?
Resistance to the poison warfarin is a genetically determined trait in rats. Homozygotes carrying the resistance allele (WRWR) have a lower fitness because they suffer from vitamin K deficiency, but heterozygotes (WRWS) do not have this deficiency. However, the heterozygotes are still resistant to warfarin. In an area where warfarin is applied, a heterozygote has a survival advantage. Due to warfarin resistance, a heterozygote is also more fit than a homozygote (WSWS) that is sensitive to warfarin. If the relative fitness values for WRWS, WRWR, and WSWS individuals are 1.0, 0.37, and 0.19, respectively, in areas where warfarin is applied, calculate the allele frequencies at equilibrium. How would this equilibrium be affected if the rats were no longer exposed to warfarin?
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Chapter 27 Solutions

Genetics: Analysis and Principles

Ch. 27.4 - 2. Which of the following influences on genetic...Ch. 27.5 - Gene flow depends on a. migration. b. the ability...Ch. 27.6 - 1. Inbreeding is sexual reproduction between...Ch. 27.7 - The mutation rate is a. the likelihood that a new...Ch. 27.7 - 2. The transfer of an antibiotic resistance gene...Ch. 27.7 - Prob. 3COMQCh. 27 - 1. What is the gene pool? How is a gene pool...Ch. 27 - Prob. 2CONQCh. 27 - Prob. 3CONQCh. 27 - Prob. 4CONQCh. 27 - The termpolymorphismcan refer to both genes and...Ch. 27 - Prob. 6CONQCh. 27 - For a gene existing in two alleles, what are the...Ch. 27 - 8.  In a population, the frequencies of two...Ch. 27 - The ability to roll your tongue is inherited as a...Ch. 27 - What evolutionary factors can cause allele...Ch. 27 - What is the difference between a neutral and an...Ch. 27 - Prob. 12CONQCh. 27 - Prob. 13CONQCh. 27 - Describe the similarities and differences among...Ch. 27 - 15.  Is each of the following examples due to...Ch. 27 - Prob. 16CONQCh. 27 - Prob. 17CONQCh. 27 - 18. A group of four birds flies to a new location...Ch. 27 - 19. Describe what happens to allele frequencies as...Ch. 27 - With regard to genetic drift, are the following...Ch. 27 - When two populations frequently intermix due to...Ch. 27 - Two populations of antelope are separated by a...Ch. 27 - Prob. 23CONQCh. 27 - 24. Using the pedigree shown here, answer the...Ch. 27 - A family pedigree is shown here. A. What is the...Ch. 27 - 26. A family pedigree is shown here. A. What is...Ch. 27 - Prob. 27CONQCh. 27 - Prob. 28CONQCh. 27 - 1. You will need to be familiar with the...Ch. 27 - You will need to refer to question 2 in More...Ch. 27 - Prob. 3EQCh. 27 - Prob. 4EQCh. 27 - You will need to refer to question 2 in More...Ch. 27 - Prob. 6EQCh. 27 - Prob. 7EQCh. 27 - In the Grants study of the medium ground finch, do...Ch. 27 - 9. A recessive lethal allele has achieved a...Ch. 27 - Among a large population of 2 million gray...Ch. 27 - In a donor population, the allele frequencies for...Ch. 27 - Prob. 12EQCh. 27 - Prob. 13EQCh. 27 - Prob. 14EQCh. 27 - 15. What would you expect to be the minimum...Ch. 27 - Discuss examples of positive and negative...Ch. 27 - Discuss the role of mutation in the origin of...Ch. 27 - Prob. 3QSDC
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