Genetics: Analysis and Principles
6th Edition
ISBN: 9781259616020
Author: Robert J. Brooker Professor Dr.
Publisher: McGraw-Hill Education
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Chapter 29, Problem 18CONQ
Take a look at the α-globin and β-globin amino acid sequences in Figure 29.11. Which sequences are more similar, the α globin in humans and the α globin in horses, or the α globin in humans and the β globin in humans? Based on your answer, would you conclude that the gene duplication that gave rise to the α-globin and β-globin genes occurred before or after the divergence of humans and horses? Explain your reasoning.
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In a study of a muscle disorder, several affected families exhibited vision problems, muscle weakness, and deafness (M. Zeviani et al. 1990. American Journal of Human Genetics 47:904–914). Analysis of the mtDNA from affected members of these families revealed that large numbers of their mtDNA molecules possessed deletions of varying lengths. Different members of the same family and even different mitochondria from the same person possessed deletions of different sizes, so the underlying defect appeared to be a tendency for the mtDNA of affected persons to have deletions. A pedigree of one of the families studied is shown below. The researchers concluded that this disorder is inherited as an autosomal dominant trait, and they mapped the diseasecausing gene to a position on chromosome 10 in the nucleus.
Q. What characteristics of the pedigree rule out inheritance of a trait encoded by a gene in the mtDNA as the cause of this disorder?
In a study of a muscle disorder, several affected families exhibited vision problems, muscle weakness, and deafness (M. Zeviani et al. 1990. American Journal of Human Genetics 47:904–914). Analysis of the mtDNA from affected members of these families revealed that large numbers of their mtDNA molecules possessed deletions of varying lengths. Different members of the same family and even different mitochondria from the same person possessed deletions of different sizes, so the underlying defect appeared to be a tendency for the mtDNA of affected persons to have deletions. A pedigree of one of the families studied is shown below. The researchers concluded that this disorder is inherited as an autosomal dominant trait, and they mapped the diseasecausing gene to a position on chromosome 10 in the nucleus.
Q. Explain how a mutation in a nuclear gene might lead to deletions in mtDNA.
What is the importance of Gregor Mendel’s Law of Inheritance in Molecular
Biology?
Chapter 29 Solutions
Genetics: Analysis and Principles
Ch. 29.1 - Prob. 1COMQCh. 29.1 - Prob. 2COMQCh. 29.1 - 3. A pair of birds flies to a deserted island and...Ch. 29.1 - Prob. 4COMQCh. 29.2 - 1. Phylogenetic trees are based on
a. natural...Ch. 29.2 - Prob. 2COMQCh. 29.2 - An approach that is used to construct a...Ch. 29.2 - 4. Horizontal gene transfer is a process in which...Ch. 29.3 - Prob. 1COMQCh. 29.3 - Prob. 2COMQ
Ch. 29.3 - When the chromosomes of closely related species...Ch. 29 - 1. Discuss the two principles on which evolution...Ch. 29 - 2. Evolution, which involves genetic changes in a...Ch. 29 - Prob. 3CONQCh. 29 - Prob. 4CONQCh. 29 - 5. Would each of the following examples of...Ch. 29 - Distinguish between anagenesis and cladogenesis....Ch. 29 - 7. Describe three or more genetic mechanisms that...Ch. 29 - Explain the type of speciation (allopatric,...Ch. 29 - Prob. 9CONQCh. 29 - Prob. 10CONQCh. 29 - Discuss the major differences among allopatric,...Ch. 29 - Prob. 12CONQCh. 29 - Prob. 13CONQCh. 29 - Would the rate of deleterious or beneficial...Ch. 29 - 15. Which would you expect to exhibit a faster...Ch. 29 - Prob. 16CONQCh. 29 - 17. Plant seeds contain storage proteins that are...Ch. 29 - Take a look at the -globin and -globin amino acid...Ch. 29 - Compare and contrast the neutral theory of...Ch. 29 - Prob. 20CONQCh. 29 - 21. As discussed in Chapter 27, genetic variation...Ch. 29 - Prob. 22CONQCh. 29 - Two populations of snakes are separated by a...Ch. 29 - 2. Sympatric speciation by allotetraploidy has...Ch. 29 - 3. Two diploid species of closely related frogs,...Ch. 29 - A researcher sequenced a portion of a bacterial...Ch. 29 - F1hybrids between two species of cotton,Gossypium...Ch. 29 - 6. A species of antelope has 20 chromosomes per...Ch. 29 - Prob. 7EQCh. 29 - 8. Prehistoric specimens often contain minute...Ch. 29 - From the results of the experiment of Figure...Ch. 29 - InChapter 23, a technique called fluorescence in...Ch. 29 - Prob. 11EQCh. 29 - 12. Discuss how the principle of parsimony can be...Ch. 29 - 13. A homologous DNA region, which was 20,000 bp...Ch. 29 - Prob. 14EQCh. 29 - Prob. 1QSDCCh. 29 - 2. Compare the forms of speciation that are slow...Ch. 29 - 3. Do you think that Darwin would object to the...
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