Cardiovascular Disease The ankle-arm blood-pressure index (AAI) is defined as the ratio of ankle systolic blood pressure/arm systolic blood pressure and is used for the diagnosis of lower extremity arterial disease. A study was conducted to investigate whether the AAI can be used as a screening test for atherosclerotic diseases in general [20]. The subjects were 446 male workers in a copper smelter in Japan. Each subject had an AAI determination as well as an electrocardiogram (ECG). From the ECG, an S-T segment depression was defined as an S-T segment ≥ 0.1 mV below the baseline in at least 1 of 12 leads in a resting ECG. S-T segment depression is often used as one characterization of an abnormal ECG. The data in Table 3.22 were presented relating AAI to S-T segment depression. Table 3.22 Association between ankle-arm blood-pressure index (AAI) and S-T segment depression Suppose the reproducibility of the AAI test were improved using better technology. Would the sensitivity of the test increase, decrease, or remain the same? why?
Cardiovascular Disease The ankle-arm blood-pressure index (AAI) is defined as the ratio of ankle systolic blood pressure/arm systolic blood pressure and is used for the diagnosis of lower extremity arterial disease. A study was conducted to investigate whether the AAI can be used as a screening test for atherosclerotic diseases in general [20]. The subjects were 446 male workers in a copper smelter in Japan. Each subject had an AAI determination as well as an electrocardiogram (ECG). From the ECG, an S-T segment depression was defined as an S-T segment ≥ 0.1 mV below the baseline in at least 1 of 12 leads in a resting ECG. S-T segment depression is often used as one characterization of an abnormal ECG. The data in Table 3.22 were presented relating AAI to S-T segment depression. Table 3.22 Association between ankle-arm blood-pressure index (AAI) and S-T segment depression Suppose the reproducibility of the AAI test were improved using better technology. Would the sensitivity of the test increase, decrease, or remain the same? why?
Solution Summary: The author explains the association between ankle-arm blood pressure index (AAI) test in not working properly. If another test or better technology is used for classifying the patients according to correct outcomes, the sensitivity value might increase.
The ankle-arm blood-pressure index (AAI) is defined as the ratio of ankle systolic blood pressure/arm systolic blood pressure and is used for the diagnosis of lower extremity arterial disease. A study was conducted to investigate whether the AAI can be used as a screening test for atherosclerotic diseases in general [20]. The subjects were 446 male workers in a copper smelter in Japan. Each subject had an AAI determination as well as an electrocardiogram (ECG). From the ECG, an S-T segment depression was defined as an S-T segment ≥ 0.1 mV below the baseline in at least 1 of 12 leads in a resting ECG. S-T segment depression is often used as one characterization of an abnormal ECG. The data in Table 3.22 were presented relating AAI to S-T segment depression.
Table 3.22 Association between ankle-arm blood-pressure index (AAI) and S-T segment depression
Suppose the reproducibility of the AAI test were improved using better technology. Would the sensitivity of the test increase, decrease, or remain the same? why?
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