Concepts of Genetics (12th Edition)
12th Edition
ISBN: 9780134604718
Author: William S. Klug, Michael R. Cummings, Charlotte A. Spencer, Michael A. Palladino, Darrell Killian
Publisher: PEARSON
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Chapter 3, Problem 19PDQ
In assessing data that fell into two
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From the pedigree shown here, answer the following questions with regard to individual VII-1.
A. Who are the common ancestors of her parents?
B. What is the inbreeding coefficient for this individual?
A geneticist, in assessing data that fell into two phenotypic classes, observed values of 250:150. He decided to perform chisquare analysis using two different null hypotheses: (a) the data fit a 3:1 ratio; and (b) the data fit a 1:1 ratio. Calculate the x2 values for each hypothesis. What can you conclude about each hypothesis?
If the chi-square value came out to 14,224.221 and the p-value was said to be less than 0.01, what do you conclude about whether these traits follow a simple Mendelian inheritance pattern? Explain your answer.
Chapter 3 Solutions
Concepts of Genetics (12th Edition)
Ch. 3 - Pigeons may exhibit a checkered or plain color...Ch. 3 - Considering the Mendelian traits round versus...Ch. 3 - Using the forked-line, or branch diagram, method,...Ch. 3 - In one of Mendels dihybrid crosses, he observed...Ch. 3 - The following pedigree is for myopia...Ch. 3 - If they seek genetic counseling, what issues would...Ch. 3 - If you were in Thomass position, would you want to...Ch. 3 - If Thomas tests positive for the HD allele, should...Ch. 3 - HOW DO WE KNOW? In this chapter, we focused on the...Ch. 3 - CONCEPT QUESTION Review the Chapter Concepts list...
Ch. 3 - Albinism in humans is inherited as a simple...Ch. 3 - Which of Mendels postulates are illustrated by the...Ch. 3 - Discuss how Mendels monohybrid results served as...Ch. 3 - What advantages were provided by Mendels choice of...Ch. 3 - Mendel crossed peas having round seeds and yellow...Ch. 3 - Based on the preceding cross, what is the...Ch. 3 - Which of Mendels postulates can only be...Ch. 3 - In a cross between a black and a white guinea pig,...Ch. 3 - What is the basis for homology among chromosomes?Ch. 3 - In Drosophila, gray body color is dominant to...Ch. 3 - How many different types of gametes can be formed...Ch. 3 - Mendel crossed peas having green seeds with peas...Ch. 3 - In a study of black guinea pigs and white guinea...Ch. 3 - Mendel crossed peas having round green seeds with...Ch. 3 - Prob. 17PDQCh. 3 - The following are F2 results of two of Mendels...Ch. 3 - In assessing data that fell into two phenotypic...Ch. 3 - Prob. 20PDQCh. 3 - Consider the following pedigree. Predict the mode...Ch. 3 - Draw all possible conclusions concerning the mode...Ch. 3 - For decades scientists have been perplexed by...Ch. 3 - A wrongful birth case was recently brought before...Ch. 3 - TaySachs disease (TSD) is an inborn error of...Ch. 3 - Datura stramonium (the Jimsonweed) expresses...Ch. 3 - The wild-type (normal) fruit fly, Drosophila...Ch. 3 - To assess Mendels law of segregation using...Ch. 3 - Albinism, caused by a mutational disruption in...Ch. 3 - (a) Assuming that Migaloos albinism is caused by a...
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Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.Similar questions
- Using the HardyWeinberg Law in Human Genetics Suppose you are monitoring the allelic and genotypic frequencies of the MN blood group locus (see Question 2 for a description of the MN blood group) in a small human population. You find that for 1-year-old children, the genotypic frequencies are MM = 0.25, MN = 0.5, and NN = 0.25, whereas the genotypic frequencies for adults are MM = 0.3, MN = 0.4, and NN = 0.3. a. Compute the M and N allele frequencies for 1-year-olds and adults. b. Are the allele frequencies in equilibrium in this population? c. Are the genotypic frequencies in equilibrium?arrow_forwardA pedigree analysis was performed on the family of a man with schizophrenia. Based on the known concordance statistics, would his MZ twin be at high risk for the disease? Would the twins risk decrease if he were raised in an environment different from that of his schizophrenic brother?arrow_forwardAssume that a Chi-square test was conducted to test the goodness of fit to a 9:3:3:1 ratio and a Chi-square value of 10.62 was obtained. Should the null hypothesis be accepted?arrow_forward
- While studying the genetics of the "Cute Faced Bat" face structure gene, three alleles ) are identified that produce 6 genotypes and 4 phenotypes “Cute”, “Super Cute Nose”, “Super Cute Face”, and “Super, Duper Cute” (equally expressing both Super Cute Face and Super Cute Nose). Given these observations, what can you conclude about the allele interactions?arrow_forwardIn assessing data that fell into two phenotypic classes, a geneticist observed values of 250:150. She decided to perform a x2 analysis by using the following two different null hypotheses: (a) the data fit a 3:1 ratio, and (b) the data fit a 1:1 ratio. Calculate the x2 values for each hypothesis. What can be concluded about each hypothesis?arrow_forwardCystic fibrosis is an autosomal recessive disease characterized by two copies of a mutated CFTR gene. If one in 100 (hypothetical scenario, not reality) people in the United States have cystic fibrosis, calculate the p and q frequency for the normal allele (p) and the mutated allele (q). Based on those calculations, what percentage of individuals would be expected to be homozygous dominant?arrow_forward
- Using the numbers provided in the attached image for the observed progeny counted for the testcross shown in the question above, perform a Chi-square analysis to determine whether you are correct as to the genotype of the unknown individual. Be sure to include a properly phrased hypothesis, the degrees of freedom, a complete Chi-square table, the Chi-square value, p-value range, and your determination of whether your hypothesis was correct.arrow_forwardWhat is the first variable that can be calculated given these data, and what is the final variable we are requesting you to calculate? "In Finland, 256 people out of 10,000 are homozygous for the CCR5 allele mutation resulting in HIV resistance. Assuming the locus is in Hardy-Weinberg equilibrium, what is the expected genotype frequency of heterozygous carriers for the CCR5 mutation?"arrow_forwardin the Hardy-Weinberg equation, what do the terms p2, q2, and 2pq represent, in terms of the genetic structure of a population?arrow_forward
- What is the mathematical expression of the genetic equilibrium for genes with two alleles? Is this statistical distribution the same as the statistical distribution of the respective phenotypes?arrow_forwardDoes Hardy-Weinberg equilibrium need to be tested for alleles resulting in only two genotypes?arrow_forwardYour friend does not believe you that the probability of losing an allele with a frequency of 0.3 is any different than losing an allele with a frequency of 0.4. Prove them wrong, mathematically. What do you assume in your answer? Is there any scenario where they are right?arrow_forward
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