(a) Interpretation: The number of atoms present in this structure is to be determined. Concept Introduction: These images are provided with the data for the representation of different variable in the structure. In PDB file of structure coordinates are used for the representation of protein, RNA and atoms and other different components present in structure.

Question

Using protein leptins' primary, secondary, and tertiary structure, explain your understanding on their differences. If you happen to mutate (change) the amino acid(s), then write or draw its possible primary, secondary and tertiary structure. Explain and compare this to the original structure of this protein.

Answer 1

Question

Chapter 30, Problem 18P

Interpretation Introduction

(a)

Interpretation:

The number of atoms present in this structure is to be determined.

Concept Introduction:

These images are provided with the data for the representation of different variable in the structure. In PDB file of structure coordinates are used for the representation of protein, RNA and atoms and other different components present in structure.

Interpretation Introduction

(b)

Interpretation:

The visibility of the bases of nucleotides that are present in the structure needs to be determined.

Concept Introduction:

These images are provided with the data for the representation of different variable in structure. In PDB file of structure coordinates are used for the representation of protein, RNA and atoms and other different components present in the structure.

Interpretation Introduction

(c)

Interpretation:

Double helical region of RNA in structure needs to be determined.

Concept Introduction:

These images are provided with the data for the representation of different variable in the structure. In PDB file of structure coordinates are used for the representation of protein, RNA and atoms and other different components present in the structure.

.

Interpretation Introduction

(d)

Interpretation:

Hit a right click on the image, after that select the ‘Select' option for all proteins. After that, again hit the right click on that image and now select ‘Render' option after this ‘Scheme' and then ‘CPK space fill' option. This results in highlighted ribosomal protein. Now, close the all protein selection tab and now select ‘Nucleic’ then select' ‘CPK space fill' from render nucleic acid. Macromolecular species which seems to pre-dominate the structure needs to be identified.

Concept Introduction:

These images are provided with the data for the representation of different variable in structure. In PDB file of structure, coordinates are used for the representation of protein, RNA and atoms and other different components present in structure.

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Using protein leptins' primary, secondary, and tertiary structure, explain your understanding on their differences. If you happen to mutate (change) the amino acid(s), then write or draw its possible primary, secondary and tertiary structure. Explain and compare this to the original structure of this protein.

(A) Give the polypeptide translation of the RNA sequence below. 5’-AUGGAAAUCAAAGUCAACCUUGAGUUUAGA-3’ (B) Write the chemical structure of the polypeptide sequence you determined in part (a) (C) Given the chemical structure of the polypeptide sequence you have written in part (b), answer True or False for each of the 5 statements below. (1) At least one of the amino acids in the sequence can undergo phosphorylation (2) The sequence looks like it could form a β turn (3) The sequence looks like it could form a β strand with one surface facing the interior of the protein and the other surface exposed to water (4) At least one of the amino acids in the polypeptide sequence can undergo oxidation to form a disulfide bridge to another polypeptide (5) The sequence looks like it could form an α helix that would be part of a coiled coil structure within a protein

True or False: Beta sheets are helical structures please explain the answer, thanks

Answer 2

Question

Chapter 30, Problem 18P

Interpretation Introduction

(a)

Interpretation:

The number of atoms present in this structure is to be determined.

Concept Introduction:

These images are provided with the data for the representation of different variable in the structure. In PDB file of structure coordinates are used for the representation of protein, RNA and atoms and other different components present in structure.

Interpretation Introduction

(b)

Interpretation:

The visibility of the bases of nucleotides that are present in the structure needs to be determined.

Concept Introduction:

These images are provided with the data for the representation of different variable in structure. In PDB file of structure coordinates are used for the representation of protein, RNA and atoms and other different components present in the structure.

Interpretation Introduction

(c)

Interpretation:

Double helical region of RNA in structure needs to be determined.

Concept Introduction:

These images are provided with the data for the representation of different variable in the structure. In PDB file of structure coordinates are used for the representation of protein, RNA and atoms and other different components present in the structure.

.

Interpretation Introduction

(d)

Interpretation:

Hit a right click on the image, after that select the ‘Select' option for all proteins. After that, again hit the right click on that image and now select ‘Render' option after this ‘Scheme' and then ‘CPK space fill' option. This results in highlighted ribosomal protein. Now, close the all protein selection tab and now select ‘Nucleic’ then select' ‘CPK space fill' from render nucleic acid. Macromolecular species which seems to pre-dominate the structure needs to be identified.

Concept Introduction:

These images are provided with the data for the representation of different variable in structure. In PDB file of structure, coordinates are used for the representation of protein, RNA and atoms and other different components present in structure.

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Answer 3

Question

Chapter 30, Problem 18P

Interpretation Introduction

(a)

Interpretation:

The number of atoms present in this structure is to be determined.

Concept Introduction:

These images are provided with the data for the representation of different variable in the structure. In PDB file of structure coordinates are used for the representation of protein, RNA and atoms and other different components present in structure.

Interpretation Introduction

(b)

Interpretation:

The visibility of the bases of nucleotides that are present in the structure needs to be determined.

Concept Introduction:

These images are provided with the data for the representation of different variable in structure. In PDB file of structure coordinates are used for the representation of protein, RNA and atoms and other different components present in the structure.

Interpretation Introduction

(c)

Interpretation:

Double helical region of RNA in structure needs to be determined.

Concept Introduction:

These images are provided with the data for the representation of different variable in the structure. In PDB file of structure coordinates are used for the representation of protein, RNA and atoms and other different components present in the structure.

.

Interpretation Introduction

(d)

Interpretation:

Hit a right click on the image, after that select the ‘Select' option for all proteins. After that, again hit the right click on that image and now select ‘Render' option after this ‘Scheme' and then ‘CPK space fill' option. This results in highlighted ribosomal protein. Now, close the all protein selection tab and now select ‘Nucleic’ then select' ‘CPK space fill' from render nucleic acid. Macromolecular species which seems to pre-dominate the structure needs to be identified.

Concept Introduction:

These images are provided with the data for the representation of different variable in structure. In PDB file of structure, coordinates are used for the representation of protein, RNA and atoms and other different components present in structure.

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Answer 4

Question

Chapter 30, Problem 18P

Interpretation Introduction

(a)

Interpretation:

The number of atoms present in this structure is to be determined.

Concept Introduction:

These images are provided with the data for the representation of different variable in the structure. In PDB file of structure coordinates are used for the representation of protein, RNA and atoms and other different components present in structure.

Interpretation Introduction

(b)

Interpretation:

The visibility of the bases of nucleotides that are present in the structure needs to be determined.

Concept Introduction:

These images are provided with the data for the representation of different variable in structure. In PDB file of structure coordinates are used for the representation of protein, RNA and atoms and other different components present in the structure.

Interpretation Introduction

(c)

Interpretation:

Double helical region of RNA in structure needs to be determined.

Concept Introduction:

These images are provided with the data for the representation of different variable in the structure. In PDB file of structure coordinates are used for the representation of protein, RNA and atoms and other different components present in the structure.

.

Interpretation Introduction

(d)

Interpretation:

Hit a right click on the image, after that select the ‘Select' option for all proteins. After that, again hit the right click on that image and now select ‘Render' option after this ‘Scheme' and then ‘CPK space fill' option. This results in highlighted ribosomal protein. Now, close the all protein selection tab and now select ‘Nucleic’ then select' ‘CPK space fill' from render nucleic acid. Macromolecular species which seems to pre-dominate the structure needs to be identified.

Concept Introduction:

These images are provided with the data for the representation of different variable in structure. In PDB file of structure, coordinates are used for the representation of protein, RNA and atoms and other different components present in structure.

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Answer 5

Chapter 30, Problem 18P

Interpretation Introduction

(a)

Interpretation:

The number of atoms present in this structure is to be determined.

Concept Introduction:

These images are provided with the data for the representation of different variable in the structure. In PDB file of structure coordinates are used for the representation of protein, RNA and atoms and other different components present in structure.

Interpretation Introduction

(b)

Interpretation:

The visibility of the bases of nucleotides that are present in the structure needs to be determined.

Concept Introduction:

These images are provided with the data for the representation of different variable in structure. In PDB file of structure coordinates are used for the representation of protein, RNA and atoms and other different components present in the structure.

Interpretation Introduction

(c)

Interpretation:

Double helical region of RNA in structure needs to be determined.

Concept Introduction:

These images are provided with the data for the representation of different variable in the structure. In PDB file of structure coordinates are used for the representation of protein, RNA and atoms and other different components present in the structure.

.

Interpretation Introduction

(d)

Interpretation:

Hit a right click on the image, after that select the ‘Select' option for all proteins. After that, again hit the right click on that image and now select ‘Render' option after this ‘Scheme' and then ‘CPK space fill' option. This results in highlighted ribosomal protein. Now, close the all protein selection tab and now select ‘Nucleic’ then select' ‘CPK space fill' from render nucleic acid. Macromolecular species which seems to pre-dominate the structure needs to be identified.

Concept Introduction:

These images are provided with the data for the representation of different variable in structure. In PDB file of structure, coordinates are used for the representation of protein, RNA and atoms and other different components present in structure.

Answer 6

Chapter 30, Problem 18P

Interpretation Introduction

(a)

Interpretation:

The number of atoms present in this structure is to be determined.

Concept Introduction:

These images are provided with the data for the representation of different variable in the structure. In PDB file of structure coordinates are used for the representation of protein, RNA and atoms and other different components present in structure.

Answer 7

Chapter 30, Problem 18P

Interpretation Introduction

(a)

Interpretation:

The number of atoms present in this structure is to be determined.

Concept Introduction:

These images are provided with the data for the representation of different variable in the structure. In PDB file of structure coordinates are used for the representation of protein, RNA and atoms and other different components present in structure.

Answer 8

Interpretation Introduction

(b)

Interpretation:

The visibility of the bases of nucleotides that are present in the structure needs to be determined.

Concept Introduction:

These images are provided with the data for the representation of different variable in structure. In PDB file of structure coordinates are used for the representation of protein, RNA and atoms and other different components present in the structure.

Answer 9

Interpretation Introduction

(b)

Interpretation:

The visibility of the bases of nucleotides that are present in the structure needs to be determined.

Concept Introduction:

These images are provided with the data for the representation of different variable in structure. In PDB file of structure coordinates are used for the representation of protein, RNA and atoms and other different components present in the structure.

Answer 10

Interpretation Introduction

(c)

Interpretation:

Double helical region of RNA in structure needs to be determined.

Concept Introduction:

These images are provided with the data for the representation of different variable in the structure. In PDB file of structure coordinates are used for the representation of protein, RNA and atoms and other different components present in the structure.

.

Answer 11

Interpretation Introduction

(c)

Interpretation:

Double helical region of RNA in structure needs to be determined.

Concept Introduction:

These images are provided with the data for the representation of different variable in the structure. In PDB file of structure coordinates are used for the representation of protein, RNA and atoms and other different components present in the structure.

.

Answer 12

Interpretation Introduction

(d)

Interpretation:

Hit a right click on the image, after that select the ‘Select' option for all proteins. After that, again hit the right click on that image and now select ‘Render' option after this ‘Scheme' and then ‘CPK space fill' option. This results in highlighted ribosomal protein. Now, close the all protein selection tab and now select ‘Nucleic’ then select' ‘CPK space fill' from render nucleic acid. Macromolecular species which seems to pre-dominate the structure needs to be identified.

Concept Introduction:

These images are provided with the data for the representation of different variable in structure. In PDB file of structure, coordinates are used for the representation of protein, RNA and atoms and other different components present in structure.

Answer 13

Interpretation Introduction

(d)

Interpretation:

Hit a right click on the image, after that select the ‘Select' option for all proteins. After that, again hit the right click on that image and now select ‘Render' option after this ‘Scheme' and then ‘CPK space fill' option. This results in highlighted ribosomal protein. Now, close the all protein selection tab and now select ‘Nucleic’ then select' ‘CPK space fill' from render nucleic acid. Macromolecular species which seems to pre-dominate the structure needs to be identified.

Concept Introduction:

These images are provided with the data for the representation of different variable in structure. In PDB file of structure, coordinates are used for the representation of protein, RNA and atoms and other different components present in structure.

Answer 14

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Answer 15

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Answer 25

Ch. 30 - Prob. 1P Ch. 30 - Prob. 2P Ch. 30 - The Second Genetic Code Review the evidence...Ch. 30 - Codon-Anticodon Recognition: Base-Pairing...Ch. 30 - Consequences of the Wobble Hypothesis Point out...Ch. 30 - Prob. 6P Ch. 30 - Prob. 7P Ch. 30 - Prob. 8P Ch. 30 - Prob. 9P Ch. 30 - The Consequences of Ribosome Complexity Eukaryotic...

Solution Summary: The author explains that the number of atoms present in the structure is to be determined.

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