Genetics: From Genes to Genomes, 5th edition
5th Edition
ISBN: 9780073525310
Author: Leland H. Hartwell, Michael L. Goldberg, Janice A. Fischer, Leroy Hood, Charles F. Aquadro
Publisher: McGraw-Hill Education
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Textbook Question
Chapter 4, Problem 15P
One of the first microscopic observations of chromosomes in cell division was published in 1905 by Nettie Stevens. Because it was hard to reproduce photographs at the time, she recorded these observations as camera lucida sketches. One such drawing, of a completely normal cell division in the mealworm Tenebrio molitor, is shown here. The techniques of the time were relatively unsophisticated by today’s standards, and they did not allow her to resolve chromosomal structures that must have been present.
a. | Describe in as much detail as possible the kind of cell division and the stage of division depicted in the drawing. |
b. | What chromosomal structure(s) cannot be resolved in the drawing? |
c. | How many chromosomes are present in normal Tenebrio molitor gametes? |
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In order to investigate the cell cycle in HEK293 cells in culture, I ran a flow cytometry experiment. I labeled their nuclei with DAPI to analyze DNA content. In these flow cytometry plots below, label the two main phases of the cell cycle that you can see. Briefly, explain your answer.
1) What phase of mitosis is this?
Answer:
2) What is the indicated structure 1? select one.
a. chromosome
b. chromosome with two sister chromatids
c. centrioles/centrosome
d. spindle fibres
e. metaphase plate
3)If the diploid (2n) number of this cell is 8 how many chromosomes are present?
4) If the diploid (2n) number of this cell is 8 how many sister chromatids are present?
5) If the diploid (2n) number of this cell is 8 how many homologous pairs are present?
Why do eukaryotic cells need to go through the elaborate procedure of mitosis rather than simply dividing during interphase? Select as many answers as apply.
1.Daughter cells must be genetically identical to the mother cell, for homeostasis and ordered tissue growth.
2.Bivalent chromosomes must condense and be separated in an orderly fashion, to allow equal distribution of copies into daughter cells
3.Physically dividing the nucleus during interphase would likely lead to gross chromosome breakage and highly unequal assortment of genetic information into daughter cells.
4.Dividing the nucleus during interphase would have the same outcome as mitosis
5.Daughter cells must have half the number of chromosomes after mitosis than the mother cells
6.The homologous pairs of chromosomes need to be separated, to ensure copies go to the daughter cells.
Chapter 4 Solutions
Genetics: From Genes to Genomes, 5th edition
Ch. 4 - Choose the best matching phrase in the right...Ch. 4 - Humans have 46 chromosomes in each somatic cell....Ch. 4 - The figure that follows shows the metaphase...Ch. 4 - XX males who are sex-reversed because they have a...Ch. 4 - Researchers discovered recently that the sole...Ch. 4 - One oak tree cell with 14 chromosomes undergoes...Ch. 4 - Indicate which of the cells numbered iv matches...Ch. 4 - a. What are the four major stages of the cell...Ch. 4 - Answer the questions that follow for each stage of...Ch. 4 - Does any reason exist that would prevent mitosis...
Ch. 4 - One oak tree cell with 14 chromosomes undergoes...Ch. 4 - Which types of cell division mitosis, meiosis I,...Ch. 4 - Complete the following statements using as many of...Ch. 4 - The five cells shown in figure a e on the next...Ch. 4 - One of the first microscopic observations of...Ch. 4 - A person is simultaneously heterozygous for two...Ch. 4 - Assuming i that the two chromosomes in homologous...Ch. 4 - In the moss Polytrichum commune, the haploid...Ch. 4 - Does any reason exist that would prevent meiosis...Ch. 4 - Sister chromatids are held together through...Ch. 4 - The pseudoautosomal regions PARs of the X and Y...Ch. 4 - Somatic cells of chimpanzees contain 48...Ch. 4 - In humans: a. How many sperm develop from 100...Ch. 4 - Women sometimes develop benign tumors called...Ch. 4 - In a certain strain of turkeys, unfertilized eggs...Ch. 4 - Imagine you have two pure-breeding lines of...Ch. 4 - A system of sex determination known as...Ch. 4 - In Drosophila, the autosomal recessive brown eye...Ch. 4 - Barred feather pattern is a Z-linked dominant...Ch. 4 - When Calvin Bridges observed a large number of...Ch. 4 - In a vial of Drosophila, a research student...Ch. 4 - In 1919, Calvin Bridges began studying an X-linked...Ch. 4 - In Drosophila, a cross was made between a...Ch. 4 - As we learned in this chapter, the white mutation...Ch. 4 - The following is a pedigree of a family in which a...Ch. 4 - Each of the four pedigrees that follow represents...Ch. 4 - The pedigree that follows indicates the occurrence...Ch. 4 - Duchenne muscular dystrophy DMD is caused by a...Ch. 4 - The X-linked gene responsible for DMD encodes a...Ch. 4 - Males have hemophilia when they are hemizygous for...Ch. 4 - Consider the following pedigrees from human...Ch. 4 - Several different antigens can be detected in...Ch. 4 - The ancestry of a white female tiger bred in a...Ch. 4 - The pedigree at the bottom of the page shows the...Ch. 4 - In 1995, doctors reported a Chinese family in...Ch. 4 - In cats, the dominant 0 allele of the X-linked...Ch. 4 - In marsupials like the opposum or kangaroo, X...Ch. 4 - The pedigree diagram below shows a family in which...
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