Human Physiology
15th Edition
ISBN: 9781259864629
Author: Fox, Stuart Ira
Publisher: Mcgraw-hill Education,
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Question
Chapter 7, Problem 8CP
Summary Introduction
To review:
Opening up of ligand gated channels with the help of nicotinic ACh (acetylcholine) receptors as a reference.
Introduction:
A neurotransmitter molecule performs the function of a ligand that fuses with its respective specific and unique receptor protein and for those ion channels that are ligand gated. This protein acts as an ion channel thus performing twin functions. For instance, there is a family of ligand gated channels which comprises five polypeptide chains around the ion channels, namely nicotinic ACh receptors.
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Explain how ligand-gated channels are opened, using nicotinic ACh receptors as an example.
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Chapter 7 Solutions
Human Physiology
Ch. 7 - Draw a neuron, label its parts, and describe the...Ch. 7 - Distinguish between sensory neurons, motor...Ch. 7 - Describe the structure of the neurilemma, and...Ch. 7 - Explain how myelin sheaths are formed in the CNS....Ch. 7 - Explain what is meant by the blood-brain barrier....Ch. 7 - Define the terms depolarization and...Ch. 7 - Prob. 4bCPCh. 7 - Describe how gating of Na+andK+ in the axon...Ch. 7 - Prob. 5aCPCh. 7 - Prob. 5bCP
Ch. 7 - Prob. 6aCPCh. 7 - Describe the location of neurotransmitters within...Ch. 7 - Describe the sequence of events by which action...Ch. 7 - Explain how chemically regulated channels differ...Ch. 7 - Prob. 8CPCh. 7 - Prob. 9aCPCh. 7 - Prob. 9bCPCh. 7 - Prob. 10CPCh. 7 - Prob. 11CPCh. 7 - Prob. 12aCPCh. 7 - Prob. 12bCPCh. 7 - Prob. 13aCPCh. 7 - Prob. 13bCPCh. 7 - Prob. 14aCPCh. 7 - Describe the mechanism of action of glycine and...Ch. 7 - Give examples of endogenous opioid polypeptides,...Ch. 7 - Prob. 15bCPCh. 7 - Prob. 16CPCh. 7 - Prob. 17aCPCh. 7 - Prob. 17bCPCh. 7 - Prob. 17cCPCh. 7 - Prob. 1RACh. 7 - Prob. 2RACh. 7 - Prob. 3RACh. 7 - Prob. 4RACh. 7 - Repolarization of an axon during an action...Ch. 7 - As the strength of a depolarizing stimulus to an...Ch. 7 - Prob. 7RACh. 7 - Which of these is not a characteristic of synaptic...Ch. 7 - Prob. 9RACh. 7 - Prob. 10RACh. 7 - Prob. 11RACh. 7 - Prob. 12RACh. 7 - Prob. 13RACh. 7 - Prob. 14RACh. 7 - Prob. 15RACh. 7 - Prob. 16RACh. 7 - Prob. 17RACh. 7 - Which of these may be produced by the action of...Ch. 7 - Prob. 19RACh. 7 - In a step-by-step manner, explain how the...Ch. 7 - Prob. 21RACh. 7 - Prob. 22RACh. 7 - Prob. 23RACh. 7 - Prob. 24RACh. 7 - Once an EPSP is produced in a dendrite, how does...Ch. 7 - Prob. 26RACh. 7 - List the endogenous opioids in the brain and...Ch. 7 - Explain what is meant by long-term potentiation...Ch. 7 - Prob. 29RACh. 7 - Prob. 30RACh. 7 - Prob. 31RACh. 7 - Prob. 32RACh. 7 - Prob. 33RACh. 7 - Explain the nature of the endocannabinoids....Ch. 7 - Prob. 35RACh. 7 - Prob. 36RACh. 7 - Prob. 37RACh. 7 - Prob. 38RACh. 7 - Prob. 39RACh. 7 - Use the figure below (from figure 7.34) to answer...
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Similar questions
- Draw and label an action potential, indicating the ion movements responsible for the rising phase and the falling phase.arrow_forwardExplain what will happen in an axon undergoing an action potential but which is unable to utilise monosaccharides for cellular respirationarrow_forwardExplain how inhibition can be produced by (a) muscarinic ACh receptors in the heart; and (b) GABAreceptors in neurons of the CNS.arrow_forward
- Describe how the permeability of the axon membrane to Na+ and K+ is regulated and how changes in permeability to these ions affect the membrane potential.arrow_forwardDescribe how gating of Na+ and K+ in the axon membrane results in the production of an action potential.arrow_forwardMuscarinic receptors binda. epinephrine.b. norepinephrine.c. acetylcholine.d. cholinesterase.e. neuropeptides.arrow_forward
- Describe the intracellular response to activation of α and β adrenergic receptorsarrow_forwardWhat are the neurotransmitters that bind to ionotropic channels and allow for cation influx? Select all that apply. Group of answer choices A. glutamate B. GABA C. dopamine D. acetylcholinearrow_forward• Why would one use the Goldman-Hodgkin-Katz equation? • What is the role of the Na+/K+ pump in establishing ionic concentration differences and membrane potentials across the nerve membrane? • Describe the process of depolarization of the nerve membrane.arrow_forward
- Give an account of signalling at a neuromuscular junction through the nicotinic acetylcholine receptor.arrow_forwardWhich statement about nicotinic acetylcholine receptors (nAChRs) is true? a. Each nAChR is composed of seven different protein subunits. b. They are ionotropic receptors and conduct Na+ and Ca2+ ions across the cell membrane causing depolarization and a fast excitatory response. c. They are ionotropic receptors and conduct K+ ions across the cell membrane, causing depolarization and a fast excitatory response. d. They are found in all areas of the nervous system except the brain.arrow_forwardCaffeine and nicotine have excitatory effects because they: reduce the threshold for excitation increase the threshold for excitation open potassium ion leakage channels open chemically-gated chloride ion channels close chemically-gated calcium ion channels ( explain deeply with step by step type the answer).arrow_forward
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