An experiment was conducted to examine the influence of avian pancreatic polypeptide (aPP), cholecystokinin (CCK), vasoactive intestinal peptide (VIP), and secretin on pancreatic and biliary secretions in laying hens. In particular, researchers were concerned with the extent to which these hormones increase or decrease biliary and pancreatic flows and their pH values.
White leghorn hens, 14−29 weeks of age, were surgically fitted with cannulas for collecting pancreatic and biliary secretions and a jugular cannula for continuous infusion of aPP, CCK, VIP, or secretin. One trial per day was conducted on a hen, as long as her implanted cannulas remained
Each trial began with infusion of physiologic saline for 20 minutes. At the end of this period, pancreatic and biliary secretions were collected and the cannulas were attached to new vials. The biliary and pancreatic flow rates (in microliters per minute) and pH values (if possible) were measured. Infusion of a hormone was then begun and continued for 40 minutes. Measurements were then repeated.
Data Set HORMONE.DAT (at www.cengagebrain com) contains data for the four hormones and saline, where saline indicates trials in which physiologic saline was infused in place of an active hormone during the second period. Each trial is one record in the file. There are 11 variables associated with each trial, as shown in Table 8.22.
Table 8.22 Format of HORMONE.DAT
Compare the changes in secretion rate or pH levels for each active hormone vs. the placebo (saline) group. Use methods of hypothesis testing and/or CIs to express these comparisons statistically.
![Check Mark](/static/check-mark.png)
Trending nowThis is a popular solution!
![Blurred answer](/static/blurred-answer.jpg)
Chapter 8 Solutions
WebAssign for Rosner's Fundamentals of Biostatistics, 8th Edition [Instant Access], Single-Term
- The Lion’sMane. In a study by P. M.West titled “The Lion’s Mane” (American Scientist, Vol. 93, No. 3, pp. 226–236), the effects of the mane of a male lion as a signal of quality to mates and rivals was explored. Four life-sized dummies of male lions provided a tool for testing female response to the unfamiliar lions whose manes varied by length (long or short) and color (blonde or dark). The female lions were observed to see whether they approached each of the four life-sized dummies. a. experimental units. b. response variable. c. factor(s). d. levels of each factor. e. treatments.arrow_forwardA recent study examined the effects of carbon monoxide exposure to a group of construction workers. The following table presents the number of workers who reported various symptoms, along with shift that they worked.arrow_forwardA study was conducted to examine the effect of diet cola consumption on calcium levels in women. A sample of 16 healthy women aged 18 to 40 were randomly assigned to drink 24 ounces of either diet cola or water. Their urine was collected for three hours after ingestion of the beverage and calcium excretion (in mg) was measured. The data are stored in ColaCalcium.arrow_forward
- Captivity can influence immunological responses in some mammals. Seeber et al. (2020) investigated various aspects of immunological responses in captive and free-ranging zebras. One aspect of the study involved samples of 12 free-ranging zebras from Namibia, 9 from Tanzania, and 38 captive zebras from various zoos in Europe. (All of these were non-lactating females.) One of the measured variables from blood samples was lysozyme concentration (μg/L). (Lysozyme is a biomarker of the immune response.) The researchers were interested in investigating possible differences in lysozyme concentration between zebras in the various locations. As part of the analysis, they carried out a one-way ANOVA on the lysozyme concentrations for the zebras from the 3 locations, and found the following output. Df Sum Sq Mean Sq F value Pr(>F) Location 2 50.65 25.33 42.24 6.54e-12Residuals 56 33.57 0.60 Suppose the assumptions of one-way ANOVA…arrow_forwardA study of the effect of caffeine on muscle metabolism used 24 male volunteers who each underwent arm exercise tests. 12 of the men were randomly selected to take a capsule containing pure caffeine one hour before the test. The other men received a placebo capsule. During each exercise the subject's respiratory exchange ratio (RER) was measured. (RER is the ratio of CO2 produced to O2 consumed and is an indicator of whether energy is being obtained from carbohydrates or fats). The question of interest to the experimenter was whether, on average, caffeine changes RER. Data is in: Placebo Caffeine 105 96 119 99 100 94 97 89 96 96 101 93 94 88 95 105 98 88 95 90 103 97 102 92 Construct a hypothesis test that detect whether there is difference in RER between two groups at .05 significant level (show steps) Construct a hypothesis test that detect whether Caffeine reduces RER compared to placebo at .05…arrow_forwardAnemia (low healthy blood cells or hemoglobin) has an important role in exercise performance. However, the direct link between rapid changes of hemoglobin and exercise performance is still unknown. A study investigated 18 patients with a blood disorder (beta-thalassemia). Participants in the study performed an exercise test before and the day after receiving a blood transfusion. Data are given in the table. HB = Hemoglobin RER = Respiratory exchange ID Change in HB Obese RER > 1.1 ratio No No 1 -1.4 No -1.5 No Yes No Yes 3 -2 No 4 -2.1 No -1.9 Yes Yes No -1.6 -1.8 -0.8 6 7 No Yes No Yes 8 9. -1 No No -1.2 No Yes 10 11 No No -0.8 -1.5 12 Yes No No Yes 13 14 -1.4 -2.6 -1.7 No No Yes Yes 15 Yes No Yes Yes 16 -2.6 No 17 18 -2.7 -1.5 Noarrow_forward
- A study of the effect of caffeine on muscle metabolism used eighteen male volunteers who each underwent arm exercise tests. Nine of the men were randomly selected to take a capsule containing pure caffeine one hour before the test. The other men received a placebo capsule. During each exercise the subject's respiratory exchange ratio (RER) was measured. (RER is the ratio of CO2 produced to O2 consumed and is an indicator of whether energy is being obtained from carbohydrates or fats). The question of interest to the experimenter was whether, on average, caffeine changes RER. The two populations being compared are “men who have not taken caffeine” and “men who have taken caffeine” the results were as follows: Develop the hypothesis, Do the test Write the result of the hypothesisarrow_forwardElissa Epel, a professor of health psychology at the University of California-San Francisco, studied women in high- and low-stress situations. She found that women with higher cortisol responses to stress ate significantly more sweet food and consumed more calories on the stress day compared with those with low cortisol responses, and compared with themselves on lower stress days. Increases in negative mood in response to the stressors were also significantly related to greater food consumption. These results suggest that psychophysiological responses to stress may influence subsequent eating behavior. Over time, these alterations could impact both weight and health. You are interested in studying whether college juniors or college sophomores consume more calories. You ask a sample of n, = 35 college juniors and n2 = 40 college sophomores to record their daily caloric intake for a week. The average daily caloric intake for college juniors was M1 2,423 calories, with a standard…arrow_forwardThe Joint Commission on Accreditation of Healthcare Organizations mandated that hospitals ban smoking by 1994. To study the effects of this ban on smoking behaviors, subjects were randomly selected from two different populations: those from hospitals with the ban and those from hospitals without the ban. Investigators were interested in determining if this smoking ban had any impact on the proportion of smokers employed at each hospital that then quit smoking. Let px be the proportion of smokers from hospitals that implemented the ban who quit smoking during the study period. Let py be the proportions of smokers from hospitals without the ban who quit smoking during the study period. Please select the appropriate hypotheses. H0: px = 0.50 HA: px ≠ 0.50 H0: px-py ≥ 0 HA: px-py H0: px-py ≤ 0 HA: px-py > 0 H0: px-py = 0 HA: px-py ≠ 0arrow_forward
- Hoaglin, Mosteller, and Tukey (1983) presented data on blood levels of beta-endorphin as a function of stress. They took beta-endorphin levels for 19 patients 12 hours before surgery and again 10 minutes before surgery. The data are presented below, in fmol/ml Based on these data, what effect does increased stressed have on endorphin levels. What type of test is this? Participant 12 hours before 10 minutes before 1 10 6.5 2 6.5 14.0 3 8.0 13.5 4 12 18 5 5.0 14.5 6 11.5 9.0 7 5.0 18.0 8 3.5…arrow_forwardSuppose a study investigated the effects of vitamin A, vitamin C, and omega-3 fatty acids supplements on improving eye health and vision. 300 adults volunteered to take part in the study. In the study, participants were randomly assigned to one of 3 different levels of Vitamin A (Level A, Level B, or Level C) and randomly assigned to one of 2 different levels of Vitamin C (Level 1 or Level 2) and randomly assigned to one of 2 different levels of omega-3 fatty acid (Level I or Level II). a. Identify the subjects of the study. b. Identify the factor(s) for the study and the number of treatment level(s) for each factor. c. How many different treatment groups are there in this study?arrow_forwardResearchers have sought to examine the effect of various types of music on agitation levels in patients who are in the early and middle stages of Alzheimer's disease. Patients were selected to participate in the study based on their stage of Alzheimer's disease. Three forms of music were tested: Easy listening, Mozart, and piano interludes. While listening to music, agitation levels were recorded for the patients with a high score indicating a higher level of agitation. Scores are recorded below. Group Piano Interlude Mozart Easy Listening Early Stage Alzheimer's 2124221820 Mean=21.0 9121059 Mean=9.0 2926302426 Mean=27.0 Middle Stage Alzheimer's 2220251820 Mean=21.0 141811913 Mean=13.0 1518201319 Mean=17.0 Complete the following ANOVA table. Source df SS MS F Type of Music 2 740 Degree of Alzheimer's 1 30 Interaction 2 260 Error 24 178 Total 29 1208…arrow_forward
- Calculus For The Life SciencesCalculusISBN:9780321964038Author:GREENWELL, Raymond N., RITCHEY, Nathan P., Lial, Margaret L.Publisher:Pearson Addison Wesley,Glencoe Algebra 1, Student Edition, 9780079039897...AlgebraISBN:9780079039897Author:CarterPublisher:McGraw HillBig Ideas Math A Bridge To Success Algebra 1: Stu...AlgebraISBN:9781680331141Author:HOUGHTON MIFFLIN HARCOURTPublisher:Houghton Mifflin Harcourt
![Text book image](https://www.bartleby.com/isbn_cover_images/9780321964038/9780321964038_smallCoverImage.gif)
![Text book image](https://www.bartleby.com/isbn_cover_images/9780079039897/9780079039897_smallCoverImage.jpg)
![Text book image](https://www.bartleby.com/isbn_cover_images/9781680331141/9781680331141_smallCoverImage.jpg)