Biochemistry
9th Edition
ISBN: 9781319114671
Author: Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher: W. H. Freeman
expand_more
expand_more
format_list_bulleted
Question
Chapter 9, Problem 15P
Interpretation Introduction
Interpretation:
The catalytic powers for subtilisin and carbonic anhydrase should be calculated.
Concept introduction:
The catalytic power of an enzyme can be found by,
Expert Solution & Answer
Want to see the full answer?
Check out a sample textbook solutionStudents have asked these similar questions
kcat = ?
an enzyme has an aspartic acid in the active site with a pKa = 4.0 and the kcat for this enzyme is directly proportional to the fraction of this side chain that is ionized. If the kcat at pH = 4.0 is 52.9x103 s-1 what is the kcat for this enzymes at pH 3.5
Serine protease enzyme mutation
To show differences in the effect of the nucleophilic attack of the carbonyl group (C=O) of peptide bond between the catalytic triad of serine, histidine and aspartic acid, and another catalytic triad contains alanine, histidine and aspartic acid
Provide/ draw an example of catalytic mechanism with catalytic triad contains alanine, histidine and aspartic
Please answer completely will give rating surely
Chymotrypsin information about enzyme?
Trivial/Common Name
Systematic (EC) name and number
Chemical reaction catalyzed
Metabolic pathway
Function and cellular localization
Size (kDa) and structure (tertiary and quaternary)
pH stability
Kinetic properties (Km- and Kcat value/s for natural substrates)
Stability and potential inhibitors
Knowledge Booster
Similar questions
- multiple choice, choose the correct answer Under which of the following conditions would an enzyme fail to be accurately described by the M-M equation:1. kcat >> k1 or k-12. In the presence of a negative allosteric effector3. At low concentrations, the reaction is first order with respect to substrate concentration4. At high concentrations the reaction is zero order with respect to substratearrow_forwardATP yield. Each of the following molecules is processed by glycolysis to lactate. How much ATP is generated from each molecule?arrow_forwardEtiology? What does that mean? What does the fact that rotenone appears to increase the susceptibility to Parkinson disease indicate about the etiology of Parkinson disease?arrow_forward
- MULTIPLE CHOICE In patients with Lesch Nyhan Syndrome, purine nucleotides are overproduced and over excreted. The hypoxanthine analogue Allopurinol, which effectively treats gout , has no effect on the severe neurological symptoms of Lesch- Nyhan patients because it does not A. decrease de novo pyrimidine synthesis B. decrease de novo purine synthesis C. decrease urate synthesis D. increase PRPP levels (Phosphoribosyl pyrophosphate)arrow_forwardWhy is the reaction rate low at pH7? Be specific and say something about the enzyme structure at the molecular level!arrow_forwardMost individuals with genetic defects in oxidative phosphorylation are found to have relatively high concentrations of alanine in their blood. how this in biochemical terms? please help :)arrow_forward
- BIOMOLECULES - MULTIPLE CHOICE - Please answer properly QUESTION : In human beings, what is the major control of de novo pyrimidine nucleotide synthesis? A. substrate availability B. competitive inhibition of carbamoyl phosphate synthetase II C. feedback inhibition of glutamine-PRPP amidotransferase D. vailability of N-acetyl glutamatearrow_forwardWhy bother to eat? What are the three primary uses for cellular energy?arrow_forwardEnzyme: Crystal Structure of Wild-Type Human Phosphoglucomutase-1 (PGM1) the description of the mechanism of how this enzyme is regulated (e.g., depending on the enzyme, the mechanism could range from being solely dependent on gene regulation to protein structure-based mechanism).arrow_forward
- Enzyme Activity and Physiological Function, The Vmax of the enzyme glycogen phosphorylase from skeletal muscle is much greater than the Vmax of the same enzyme from liver tissue. (a) What is the physiological function of glycogen phosphorylase in skeletal muscle?arrow_forwardIsoform of Lactate dehydrogenase LDHarrow_forwardwool consists of alpha keratin, pure wool sweaters exposed to hot water shrink alarmingly, after shrinkage, it is virtually impossible to stretch the seweater back to its original shape, what do you think is the biochemical cause of this phenomenon?arrow_forward
arrow_back_ios
SEE MORE QUESTIONS
arrow_forward_ios
Recommended textbooks for you
- BiochemistryBiochemistryISBN:9781305577206Author:Reginald H. Garrett, Charles M. GrishamPublisher:Cengage Learning
Biochemistry
Biochemistry
ISBN:9781305577206
Author:Reginald H. Garrett, Charles M. Grisham
Publisher:Cengage Learning