Biochemistry: Molecular. -Std. S. G. Solutions Format: Paperback
6th Edition
ISBN: 9780190209919
Author: MCKEE
Publisher: Oxford University Press
expand_more
expand_more
format_list_bulleted
Question
Chapter 9, Problem 8RQ
Summary Introduction
To review:
The process of transfer of acetyl-CoA(coenzyme A) from mitochondria to the cytoplasm for fatty acid synthesis.
Introduction:
Acetyl-CoA is produced from pyruvate in the mitochondria by the enzyme, pyruvate dehydrogenase. Acetyl-CoA is the precursor for citric acid synthesis. This molecule also helps in fatty acid synthesis that takes place in the cytoplasm. In order to take part in the fatty acid synthesi, scetyl-CoA gets transported to cytoplasm from mitochondria.
Expert Solution & Answer
Want to see the full answer?
Check out a sample textbook solutionStudents have asked these similar questions
In the glyoxylate cycle, two molecules of acetyl-CoA areconverted into _______________ and malate.
_____________ pathways can function in both anabolic and catabolic processes.
_____________ is a small matrix protein that functions as an electron acceptor for dehydrogenases in fatty acid oxidation.
Chapter 9 Solutions
Biochemistry: Molecular. -Std. S. G. Solutions Format: Paperback
Ch. 9 - Prob. 1QCh. 9 - Prob. 2QCh. 9 - Prob. 3QCh. 9 - Prob. 4QCh. 9 - Prob. 5QCh. 9 - Prob. 6QCh. 9 - Prob. 7QCh. 9 - Prob. 1RQCh. 9 - Prob. 2RQCh. 9 - Prob. 3RQ
Ch. 9 - Prob. 4RQCh. 9 - Prob. 5RQCh. 9 - Prob. 6RQCh. 9 - Prob. 7RQCh. 9 - Prob. 8RQCh. 9 - Prob. 9RQCh. 9 - Prob. 10RQCh. 9 - Prob. 11RQCh. 9 - Prob. 12RQCh. 9 - Prob. 13RQCh. 9 - Prob. 14RQCh. 9 - Prob. 15RQCh. 9 - Prob. 16RQCh. 9 - Prob. 17RQCh. 9 - Prob. 18RQCh. 9 - Prob. 19RQCh. 9 - Prob. 20RQCh. 9 - Prob. 21RQCh. 9 - Prob. 22RQCh. 9 - Prob. 23RQCh. 9 - Prob. 24RQCh. 9 - Prob. 25RQCh. 9 - Prob. 26RQCh. 9 - Prob. 27RQCh. 9 - Prob. 28FBCh. 9 - Prob. 29FBCh. 9 - Prob. 30FBCh. 9 - Prob. 31FBCh. 9 - Prob. 32FBCh. 9 - Prob. 33FBCh. 9 - Prob. 34FBCh. 9 - Prob. 35FBCh. 9 - Prob. 36FBCh. 9 - Prob. 37FBCh. 9 - Prob. 38SACh. 9 - Prob. 39SACh. 9 - Prob. 40SACh. 9 - Prob. 41SACh. 9 - Prob. 42SACh. 9 - Prob. 43TQCh. 9 - Prob. 44TQCh. 9 - Prob. 45TQCh. 9 - Prob. 46TQCh. 9 - Prob. 47TQCh. 9 - Prob. 48TQCh. 9 - Prob. 49TQCh. 9 - Prob. 50TQCh. 9 - Prob. 51TQCh. 9 - Prob. 52TQCh. 9 - Prob. 53TQCh. 9 - Prob. 54TQCh. 9 - Prob. 55TQCh. 9 - Prob. 56TQCh. 9 - Prob. 57TQCh. 9 - Prob. 58TQCh. 9 - Prob. 59TQ
Knowledge Booster
Similar questions
- The carrier of molecules of carbon dioxide in fatty acid synthesis is _____________.arrow_forwardQuestion #15 Which of the following transporters we discussed in this part of the course transports a phosphorylated metabolite? A) The GLUT transporter in liver cells B) The pyruvate transporter involved in the first gluconeogenesis bypass in mitochondria C) Glucose 6-phosphatase D) The G6-P transporter (also known as T1) in liver cells E) The malate transporters involved in the first gluconeogenesis bypass in mitochondria Question # 16: Which of the follou ells to mairarrow_forwardThe pyruvate dehydrogenase complex catalyzes the oxidative decarboxylation of pyruvate to form acetyl‑CoA. E1E1 , E2E2 , and E3E3 are abbreviations for the enzymes of the complex. Classify the enzyme names, prosthetic groups, and reactions as E1E1 , E2E2 , or E3E3 .arrow_forward
- QUESTION 12.10 Identify each of the following biomolecules: H HN `NH CH3 -CH2 COA-S CH2 CH3 S-ACP -R (a) (b) (c) (d) What is the function of each?arrow_forwardA metabolic pathway that functions in both anabolic andcatabolic processes is called an _____________________pathway.arrow_forwardWhen transaminated, the three branched-chain amino acids (valine, leucine, and isoleucine) form compounds that have the characteristic odor of maple syrup. An enzyme known as branched-chain a-keto acid dehydrogenase converts these compounds into CoA esters. People who do not have this enzyme have the genetic disease known as maple syrup urine disease, so called because their urine smells like maple syrup. a. Draw the compounds that smell like maple syrup.b. Draw the CoA esters.c. Branched-chain a-keto acid dehydrogenase has five coenzymes. Identify them.d. Suggest a way to treat maple syrup urine disease.arrow_forward
- Cells that lack mitochondrial PEP carboxykinase transferoxaloacetate into the cytoplasm using the ________________shuttle.arrow_forwardAmino acids that degrade yielding acetyl-CoA or acetoacetyl-CoA are referred to as _____________.arrow_forwardPhosphoglucokinase catalyzes the phosphorylation of the C6-OH group of G1P. Why is this enzyme important for the normal function of phosphoglucomutase?arrow_forward
- What is succinate dehydrogenase (SDH)? How is it useful in determining mitochondria activity in your collected solutions?arrow_forwardProstaglandins are a class of eicosanoids, fatty acid derivatives with a variety of extremely potent actions on vertebrate tissues. They are responsible for producing fever and inflammation and its associated pain. Prostaglandins are derived from the 20-carbon fatty acid arachidonic acid in a reaction catalyzed by the enzyme prostaglandin endoperoxide synthase. This enzyme, a cyclooxygenase, uses oxygen to convert arachidonic acid to PGG2, the immediate precursor of many different prostaglandins. Arachidonic Rate of formation Rate of formation of PGG2 with 10 mg/ml acid (mM) of PGG2 (mM/min) ibuprofen (mM/min) 0.280 15.3 9.58 0.336 17.3 11.0 0.504 21.8 14.8 0.840 27.6 20.3 1.96 35.8 29.8 The kinetic data given in the table are for the reaction catalyzed by a mutant of prostaglandin endoperoxide synthase. Focusing here on the first two columns, determine the Vmax and Km of the enzyme. mM/min Vmax %3Darrow_forwardProstaglandins are a class of eicosanoids, fatty acid derivatives with a variety of extremely potent actions on vertebrate tissues. They are responsible for producing fever and inflammation and its associated pain.Prostaglandins are derived from the 20-carbon fatty acid arachidonic acid in a reaction catalyzed by the enzyme prostaglandin endoperoxide synthase. This enzyme, a cyclooxygenase, uses oxygen to convert arachidonic acid to PGG2 , the immediate precursor of many different prostaglandins .(a) The kinetic data given below are for the reaction catalyzed by prostaglandin endoperoxide synthase. Focusing here on the first two columns, determine the Vmax and Km of the enzyme. (b) Ibuprofen is an inhibitor of prostaglandin endoperoxide synthase. By inhibiting the synthesis of prostaglandins, ibuprofen reduces inflammation and pain. Using the data in the first and third columns of the table, determine the type of inhibition that ibuprofen exerts on prostaglandin endoperoxide synthase.arrow_forward
arrow_back_ios
SEE MORE QUESTIONS
arrow_forward_ios
Recommended textbooks for you
- BiochemistryBiochemistryISBN:9781319114671Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.Publisher:W. H. FreemanLehninger Principles of BiochemistryBiochemistryISBN:9781464126116Author:David L. Nelson, Michael M. CoxPublisher:W. H. FreemanFundamentals of Biochemistry: Life at the Molecul...BiochemistryISBN:9781118918401Author:Donald Voet, Judith G. Voet, Charlotte W. PrattPublisher:WILEY
- BiochemistryBiochemistryISBN:9781305961135Author:Mary K. Campbell, Shawn O. Farrell, Owen M. McDougalPublisher:Cengage LearningBiochemistryBiochemistryISBN:9781305577206Author:Reginald H. Garrett, Charles M. GrishamPublisher:Cengage LearningFundamentals of General, Organic, and Biological ...BiochemistryISBN:9780134015187Author:John E. McMurry, David S. Ballantine, Carl A. Hoeger, Virginia E. PetersonPublisher:PEARSON
Biochemistry
Biochemistry
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:W. H. Freeman
Lehninger Principles of Biochemistry
Biochemistry
ISBN:9781464126116
Author:David L. Nelson, Michael M. Cox
Publisher:W. H. Freeman
Fundamentals of Biochemistry: Life at the Molecul...
Biochemistry
ISBN:9781118918401
Author:Donald Voet, Judith G. Voet, Charlotte W. Pratt
Publisher:WILEY
Biochemistry
Biochemistry
ISBN:9781305961135
Author:Mary K. Campbell, Shawn O. Farrell, Owen M. McDougal
Publisher:Cengage Learning
Biochemistry
Biochemistry
ISBN:9781305577206
Author:Reginald H. Garrett, Charles M. Grisham
Publisher:Cengage Learning
Fundamentals of General, Organic, and Biological ...
Biochemistry
ISBN:9780134015187
Author:John E. McMurry, David S. Ballantine, Carl A. Hoeger, Virginia E. Peterson
Publisher:PEARSON