Concept explainers
(a)
Interpretation:
The residue in the active site of elastase that is most likely to form a covalent bond with the
Concept introduction:
The organic compounds that contain
(b)
Interpretation:
The type of covalent link that would be formed between residue and aldehyde is to be identified.
Concept introduction:
Acetal is an organic compound with general formula
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- On the trail of carbons. Tissue culture cells were incubated with glutamine labeled with 15NN in the amide group. Subsequently, IMP was isolated and found to contain some 15N.N. Which atoms in IMP were labeled?arrow_forwardNeed help, please.arrow_forwardChemical labeling of chymotrypsin by the compound tosylphenylalanine chloromethyl ketone (TPCK) modifies the His 57 in the enzyme's active site. The structure of this derivative is shown below. TPCK inactivates the enzyme because the bulky addition prevents it from cleaving nearby covalent bonds. HCI + CH, C-O Chymotrypsin-His 57 TPCK Modified enzyme True O Falsearrow_forward
- I. Active site analysis. Below is a diagram of a putative active site for Monoamine oxidase. As we learned, the purpose of tertiary structure is to form a scaffold so you can orient just a few amino acids in the right orientation to promote binding and/or catalysis. The position where this occurs is the active site. The amino acid architecture of an active site is designed to bind substrates. Amino acid side chains are capable of hydrogen bonding, ionic and hydrophobic interactions. Fill in each amino acid that you think is suitable for interacting with the part of the substrate it is closest to. Assume the pH will be at 7.0 a.a.#1 a.a.#2 a.a.#6 HO Lond NH₂ НО a.a.#5 OH a.a.#3 a.a.#4arrow_forwardSweet proteins. List the key classes of glycoproteins, their defining characteristics, and their biological functions.arrow_forwardStep by step explain. Asaparrow_forward
- Only galactose need. Solve like samplearrow_forwardFor 100 words. What are the two essential requirements to effectively carry out metabolic work?arrow_forwardMORSE TYPE. The following questions are associated with given headings. There are three descriptions per heading. Assess and answer by choosing from the choices below. ROPERTIES OF FATTY ACIDS: I. Contains polar hydrocarbon and nonpolar carboxyl groups II. Carboxyl portion undergoes halogenation III. Forms ester bond on the hydrocarbon chain CHOICES: I onlyII onlyIII onlyI and IIII and IIII and IIII, II, IIINone of the above 2. PROPERTIES OF POLYUNSATURATED FATS: I. Forms single bonds and double bonds with hydrogen II. Undergo hydrogenation on bonds saturated with hydrogen III. Hardens when saturated with hydrogen, CHOICES: I onlyII onlyIII onlyI and IIII and IIII and IIII, II, IIINone of the above 3. OXIDATION: I. Saturated fats are more susceptible II. Degree of oxidation can be measured by acid value determination III. Can be avoided by adding a natural anti-oxidant, BHA CHOICES: I onlyII onlyIII onlyI and IIII and IIII and IIII, II, IIINone of the above 4. TRIGLYCERIDE:…arrow_forward
- BiochemistryBiochemistryISBN:9781305577206Author:Reginald H. Garrett, Charles M. GrishamPublisher:Cengage Learning