Principles of Biology
Principles of Biology
2nd Edition
ISBN: 9781259875120
Author: Robert Brooker, Eric P. Widmaier Dr., Linda Graham Dr. Ph.D., Peter Stiling Dr. Ph.D.
Publisher: McGraw-Hill Education
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Chapter 9.6, Problem 2TYK

Which of the following is the correct order for the progression of chromatin compaction seen in metaphase chromosomes?

  1. radial loop domains, further compaction of radial loop domains, nucleosomes, 30-nm fiber
  2. radial loop domains, further compaction of radial loop domains, 30- nm fiber, nucleosomes
  3. nucleosomes, 30-nm fiber, radial loop domains, further compaction of radial loop domains
  4. 30-nm fiber, nucleosomes, radial loop domains, further compaction of radial loop domains

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What is the relation between the concepts of chromatin andchromosome? Are euchromatin and heterochromatin part of chromosomes?
Draw and label G1 and G2 stages of interphase and each stage of mitosis (in order) for a cell that has two large and two small chromosomes, 2n=4. For unreplicated chromosome draw a line ( / ) and for replicated chromosome draw an X. Since we are focusing on the DNA, you can skip drawing the nuclear membrane or spindle fibers. For simplicity, do not indicate that the chromosomes are decondensed chromatin during interphase.  Mark and label a place on one of the large chromosomes with the dominant allele of the “A” gene and put the recessive allele “a” on the other homolog. Mark and label a place on one of the small chromosomes with allele “B” and put the recessive allele “b” on the other homolog.
The term heterochromatin refers to heavily condensed regions of chromosomes that are largely devoid of genes.  Since few genes exist there, these regions almost never decondense for transcription. At what point during the cell cycle would expect  to observe decondensation of heterochromatic regions? Why?
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