(i)When there is a deficiency of thiamine, blood levels of pyruvate and a- ketoglutarateincrease, especially after a high-glucose meal . Explain the observations mentioned.(ii) Explain how El of pyruvate dehydrogenase complex is regulated using covalentmodification

After a high glucose diet, glucose is utilized or glycolysis whose end product is pyruvate. Pyruvate…

Answered: (i) When there is a deficiency of…

Biochemistry

6th Edition

ISBN:9781305577206

Author:Reginald H. Garrett, Charles M. Grisham

Publisher:Reginald H. Garrett, Charles M. Grisham

Chapter18: Glycolysis

Section: Chapter Questions

Problem 7P: The Effect of lodoacetic Acid on the Glyceraldehyde-3-P Dehydrogenase Reaction (Integrates with...

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(i) When there is a deficiency of thiamine, blood levels of pyruvate and a- ketoglutarate increase, especially after a high-glucose meal . Explain the observations mentioned. (ii) Explain how El of pyruvate dehydrogenase complex is regulated using covalent modification