Biology 2e
2nd Edition
ISBN: 9781947172517
Author: Matthew Douglas, Jung Choi, Mary Ann Clark
Publisher: OpenStax
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Textbook Question
Chapter 10, Problem 21RQ
Which negative regulatory molecule can trigger cell suicide (apoptosis) if vital cell cycle events do not occur?
- p53
- p21
- retinoblastoma protein (Rb)
- cyclin-dependent kinase (Cdk)
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Which negative regulatory molecule can trigger cell suicide (apoptosis) if vital cell cycle events do not occur? a. p53 b. p21 c. retinoblastoma protein (Rb) d. cyclin-dependent kinase (Cdk)
In a healthy cell, which of the following proteins will be activated in order to suppress cell division if the cell is not ready or should not divide?
Select one:
a.
p53
b.
cdk
c.
cyclin
d.
seperase
e.
mitogen
Which of the following would lead to increased progression through the G1/S cell cycle check point?
CDK is produced at lower than normal levels.
E2F is produced at lower than normal levels.
Cyclin D and E are produced at lower than normal levels.
Retinoblastoma protein was never phosphorylated.
Retinoblastoma protein is produced at lower than normal levels.
Chapter 10 Solutions
Biology 2e
Ch. 10 - Figure 10.6 Which of the following is the correct...Ch. 10 - Figure 10.13 Rb and other proteins that negatively...Ch. 10 - Figure 10.14 Human papillomavirus can cause...Ch. 10 - A diploid cell has ________ the number of...Ch. 10 - An organism s traits are determined by the...Ch. 10 - The first level of DNA organization in a...Ch. 10 - Identical copies of chromatin held together by...Ch. 10 - S. Chromosomes are duplicated during what stage of...Ch. 10 - Which of the following events does not occur...Ch. 10 - The mitotic spindles arise from which cell...
Ch. 10 - Attachment of the mitotic spindle fibers to the...Ch. 10 - Unpacking of chromosomes and the formation of a...Ch. 10 - Separation of the sister chromatids is a...Ch. 10 - The chromosomes become visible under a light...Ch. 10 - The fusing of Golgi vesicles at the metaplhase...Ch. 10 - At which of the cell-cycle checkpoints do external...Ch. 10 - What is the main prerequisite for clearance at the...Ch. 10 - If the M checkpoint is not cleared, what stage of...Ch. 10 - Which protein is a positive regulator that...Ch. 10 - Many of the negative regulator proteins of the...Ch. 10 - Which negative regulatory molecule can trigger...Ch. 10 - are changes to the order of nucleotides in a...Ch. 10 - A gene that codes for a positive cell-cycle...Ch. 10 - A mutated gene that codes for an altered version...Ch. 10 - Which molecule is a Cdk inhibitor that is...Ch. 10 - Which eukaryotic cell-cycle event is missing in...Ch. 10 - FtsZ proteins direct the formation of a...Ch. 10 - Compare and contrast a human somatic cell to a...Ch. 10 - What is the relationship between a genome,...Ch. 10 - Eukaryotic chromosomes are thousands of times...Ch. 10 - Briefly describe the events that occur in each...Ch. 10 - Chemotherapy drugs such as vincristine (derived...Ch. 10 - Describe the similarities and differences between...Ch. 10 - List some reasons why a cell that has just...Ch. 10 - What cell-cycle events will be affected in a cell...Ch. 10 - Describe the general conditions that must be met...Ch. 10 - Compare and contrast the roles of the positive...Ch. 10 - What steps are necessary for Cdk to become fully...Ch. 10 - Rb is a negative regulator that blocks the cell...Ch. 10 - Outline the steps that lead to a cell becoming...Ch. 10 - Explain the difference between a proto-oncogene...Ch. 10 - List the regulatory mechanisms that might be lost...Ch. 10 - ______ can trigger apoptosis if certain cell-cycle...Ch. 10 - Name the common components of eukaryotic cell...Ch. 10 - Describe how the duplicated bacterial chromosomes...
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- Oscillations in the activity of which protein family propels the cell cycle forward and creates abrupt transitions between different cell cycle states? prophases kinetochores cyclin-dependent kinases microtubulesarrow_forwardThe cell cycle normally stops within the G1 phase of interphase unless the cell receives a go-ahead signal via certain control proteins. If that signal never arrives,the cell will switch into a permanently nondividing state. Select one: True Falsearrow_forwardIndicate whether each of the following statements related is likely to be true or false Similar to the Cdks, when activated, the anaphase-promoting complex phosphorylates its targets. The level of M-cyclin is constant throughout the cell cycle.arrow_forward
- At which of the cell-cycle checkpoints do external forces have the greatest influence? a. G1 checkpoint b. G2 checkpoint c. M checkpoint d. G0 checkpointarrow_forwardIn your own words, explain how cancer cells differ from normal cells in regard to the following: Molecular controls of the cell cycle (include Cdk and Cdk/cyclin complexes, p53 gene/protein, Rb gene/protein in response)arrow_forwardThe absence of p53 ____ the cell cycle. The absence of retinoblastoma ____ the cell cycle. Select one: a. promotes, promotes b. inhibits, promotes c. promotes, inhibits d. inhibits, inhibitsarrow_forward
- Which of the following is NOT a checkpoint that controls the progression of cell cycle? The metaphase checkpoint determines if all chromosomes are attached to the spindle apparatus Cytokinesis involves the formation of cleavage furrow to separate the cells The G2 checkpoint checks for DNA damage and determines if all of the DNA is replicated Cyclins and cyclin dependent kinases are protejns that are responsible for advancing a cell through the phases of the cell cyclearrow_forwardWhich of the following statements is true regarding cell cycle regulators? a. Cyclins determine which proteins each Cdks will act on. b. Cdks check the DNA for damage and repairs it. c. Cyclin binding to Cdks will result to Cdk inactivation. d. Cyclin levels remain constant through the cell cycle.arrow_forwardNormally functioning cell cycle regulators are molecular signals that do all of the following EXCEPT: Inhibit progression through the cell cycle Stimulate progression through the cell cycle Instruct cells to progress from M phase directly to G2 phase during the cell cycle Instruct cells to initiate programmed cell death during development Instruct cells to differentiate during developmentarrow_forward
- Fill in the blanks with the appropriate word/ phrase that correspond to each cell cycle check point.arrow_forwardCell cycle regulation does NOT include: - Checkpoints are certain intervals -Proteins that survey the cell for errors -Verifying the cell is big enough to divide -Using enzymes to cut up DNA into chunks immediately before cell divisionarrow_forwardWhat is a role of cyclines in regulating the cell cycle? Describe the significance of checkpoints monitoring proteins check for aberrant cell cycle events.arrow_forward
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