Biology 2e
2nd Edition
ISBN: 9781947172517
Author: Matthew Douglas, Jung Choi, Mary Ann Clark
Publisher: OpenStax
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Textbook Question
Chapter 10, Problem 24RQ
A mutated gene that codes for an altered version of Cdk that is active in the absence of cyclin is a(n) ___________ .
- kinase inhibitor
- tumor suppressor gene
- proto-oncogene
- oncogene.
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Chapter 10 Solutions
Biology 2e
Ch. 10 - Figure 10.6 Which of the following is the correct...Ch. 10 - Figure 10.13 Rb and other proteins that negatively...Ch. 10 - Figure 10.14 Human papillomavirus can cause...Ch. 10 - A diploid cell has ________ the number of...Ch. 10 - An organism s traits are determined by the...Ch. 10 - The first level of DNA organization in a...Ch. 10 - Identical copies of chromatin held together by...Ch. 10 - S. Chromosomes are duplicated during what stage of...Ch. 10 - Which of the following events does not occur...Ch. 10 - The mitotic spindles arise from which cell...
Ch. 10 - Attachment of the mitotic spindle fibers to the...Ch. 10 - Unpacking of chromosomes and the formation of a...Ch. 10 - Separation of the sister chromatids is a...Ch. 10 - The chromosomes become visible under a light...Ch. 10 - The fusing of Golgi vesicles at the metaplhase...Ch. 10 - At which of the cell-cycle checkpoints do external...Ch. 10 - What is the main prerequisite for clearance at the...Ch. 10 - If the M checkpoint is not cleared, what stage of...Ch. 10 - Which protein is a positive regulator that...Ch. 10 - Many of the negative regulator proteins of the...Ch. 10 - Which negative regulatory molecule can trigger...Ch. 10 - are changes to the order of nucleotides in a...Ch. 10 - A gene that codes for a positive cell-cycle...Ch. 10 - A mutated gene that codes for an altered version...Ch. 10 - Which molecule is a Cdk inhibitor that is...Ch. 10 - Which eukaryotic cell-cycle event is missing in...Ch. 10 - FtsZ proteins direct the formation of a...Ch. 10 - Compare and contrast a human somatic cell to a...Ch. 10 - What is the relationship between a genome,...Ch. 10 - Eukaryotic chromosomes are thousands of times...Ch. 10 - Briefly describe the events that occur in each...Ch. 10 - Chemotherapy drugs such as vincristine (derived...Ch. 10 - Describe the similarities and differences between...Ch. 10 - List some reasons why a cell that has just...Ch. 10 - What cell-cycle events will be affected in a cell...Ch. 10 - Describe the general conditions that must be met...Ch. 10 - Compare and contrast the roles of the positive...Ch. 10 - What steps are necessary for Cdk to become fully...Ch. 10 - Rb is a negative regulator that blocks the cell...Ch. 10 - Outline the steps that lead to a cell becoming...Ch. 10 - Explain the difference between a proto-oncogene...Ch. 10 - List the regulatory mechanisms that might be lost...Ch. 10 - ______ can trigger apoptosis if certain cell-cycle...Ch. 10 - Name the common components of eukaryotic cell...Ch. 10 - Describe how the duplicated bacterial chromosomes...
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- "In the cellular regulatory pathways that control cell growth and proliferation, the products of oncogenes are stimulatory components and the products of tumor suppressor genes are inhibitory components" is true or false.arrow_forwardLoss of heterozygosity of tumor suppressor gene_______________arrow_forwardThe genes for retinoblastoma (pRB) and p53, act as ________ in regulating the cell cycle. oncogenes proto-oncogenes pseudo-oncogenes tumor enhancer genes tumor suppressor genesarrow_forward
- A normally functioning gene that regulates the cell cycle by stopping cell division is most likely to be a(n) __________. Group of answer choices carcino-gene tumor suppressor proto-oncogene muta-gene oncogenearrow_forwardHenrietta Lacks was female, so, naturally, all the cells from her derived cancerous cell line have _______ chromosomes.arrow_forwardExplain why mutations in tumor suppressor genes are recessive (both copies of the gene must be defective for the regulation of cell division to be defective), whereas mutations in oncogenes are dominant.arrow_forward
- _____________________ describes the imbalance in genetic information due to the removal of controls at cell cycle checkpoints. Group of answer choices Tumor mosaicism Oncogene Benign tumor Genomic instabilityarrow_forwardAnswer each question with a paragraph; 3-5 sentences each. Explain the difference between a proto-oncogene and a tumor-suppressor gene. Explain the difference between prokaryotic and eukaryotic cell division. Explain the difference between positive regulation of the cell cycle and negative regulation of the cell cycle. Explain the difference between normal p53 and mutated p53. Find two differences and two similarities between binary fission and mitosis.arrow_forwardGas pedal that works normally and helps the cell to divide can be compare to what kind of gene ? Is it oncogene , proto - oncogene or tumor suppressor gene ? Explain your answer.arrow_forward
- True or false: When oncogenes are present, a cell is more likely to be normal (non-cancerous) than when they are not present.arrow_forwardWhich of these events do you think is likely to promote tumorigenesis in affected cells? Group of answer choices DNA methylation of the promoter region of a tumor suppressor gene Hypermethylation of transcription factors that antagonize Wntsignaling Open chromatin in the region of of DNA harboring an activating mutation of beta-catenin All of thesearrow_forwardCompare and contrast oncogenes versus tumor-suppressorgenes.arrow_forward
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