Biology 2e
2nd Edition
ISBN: 9781947172517
Author: Matthew Douglas, Jung Choi, Mary Ann Clark
Publisher: OpenStax
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Textbook Question
Chapter 10, Problem 25RQ
Which molecule is a Cdk inhibitor that is controlled by p53?
- cyclin
- anti-kinase
- Rb
- p21
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Which molecule is a Cdk inhibitor that is controlled by p53? a. cyclin b. anti-kinase c. Rb d. p21
Which protein is a positive regulator that phosphorylates other proteins when activated? a. p53 b. retinoblastoma protein (Rb) c. cyclin d. cyclin-dependent kinase (Cdk)
Which negative regulatory molecule can trigger cell suicide (apoptosis) if vital cell cycle events do not occur? a. p53 b. p21 c. retinoblastoma protein (Rb) d. cyclin-dependent kinase (Cdk)
Chapter 10 Solutions
Biology 2e
Ch. 10 - Figure 10.6 Which of the following is the correct...Ch. 10 - Figure 10.13 Rb and other proteins that negatively...Ch. 10 - Figure 10.14 Human papillomavirus can cause...Ch. 10 - A diploid cell has ________ the number of...Ch. 10 - An organism s traits are determined by the...Ch. 10 - The first level of DNA organization in a...Ch. 10 - Identical copies of chromatin held together by...Ch. 10 - S. Chromosomes are duplicated during what stage of...Ch. 10 - Which of the following events does not occur...Ch. 10 - The mitotic spindles arise from which cell...
Ch. 10 - Attachment of the mitotic spindle fibers to the...Ch. 10 - Unpacking of chromosomes and the formation of a...Ch. 10 - Separation of the sister chromatids is a...Ch. 10 - The chromosomes become visible under a light...Ch. 10 - The fusing of Golgi vesicles at the metaplhase...Ch. 10 - At which of the cell-cycle checkpoints do external...Ch. 10 - What is the main prerequisite for clearance at the...Ch. 10 - If the M checkpoint is not cleared, what stage of...Ch. 10 - Which protein is a positive regulator that...Ch. 10 - Many of the negative regulator proteins of the...Ch. 10 - Which negative regulatory molecule can trigger...Ch. 10 - are changes to the order of nucleotides in a...Ch. 10 - A gene that codes for a positive cell-cycle...Ch. 10 - A mutated gene that codes for an altered version...Ch. 10 - Which molecule is a Cdk inhibitor that is...Ch. 10 - Which eukaryotic cell-cycle event is missing in...Ch. 10 - FtsZ proteins direct the formation of a...Ch. 10 - Compare and contrast a human somatic cell to a...Ch. 10 - What is the relationship between a genome,...Ch. 10 - Eukaryotic chromosomes are thousands of times...Ch. 10 - Briefly describe the events that occur in each...Ch. 10 - Chemotherapy drugs such as vincristine (derived...Ch. 10 - Describe the similarities and differences between...Ch. 10 - List some reasons why a cell that has just...Ch. 10 - What cell-cycle events will be affected in a cell...Ch. 10 - Describe the general conditions that must be met...Ch. 10 - Compare and contrast the roles of the positive...Ch. 10 - What steps are necessary for Cdk to become fully...Ch. 10 - Rb is a negative regulator that blocks the cell...Ch. 10 - Outline the steps that lead to a cell becoming...Ch. 10 - Explain the difference between a proto-oncogene...Ch. 10 - List the regulatory mechanisms that might be lost...Ch. 10 - ______ can trigger apoptosis if certain cell-cycle...Ch. 10 - Name the common components of eukaryotic cell...Ch. 10 - Describe how the duplicated bacterial chromosomes...
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- Apoptosis can occur in a cell when the cell is damaged no longer needed infected by a virus all of the abovearrow_forwardA gene that codes for a positive cell cycle regulator is called a(n) _______. a. kinase inhibitor b. tumor suppressor gene c. proto-oncogene d. oncogenearrow_forwardThe protein that ensures the fidelity of DNA replication is the a. tumor repressor P53 protein. b. Mitotic arrest deficient protein. c. transcription factor E2F protein. d. Ataxia telangiectasia mutated protein.arrow_forward
- Which of the following types of mutations would be most likely to cause cells to undergo apoptosis (programmed cell death)? One that increases the affinity of p21 for Cdks One that decreases the affinity of Rb for the transcription factor E2F One that decreases the ability of p53 to bind to DNA One that causes p53 to be constitutively phosphorylatedarrow_forwardWhich of the following must occur for programmed cell death (apoptosis): 1. p53 must be stabilized 2. M-Cdk must be active 3. Caspases must be inactivated 4. There must be local inflammationarrow_forwardIn a healthy cell, which of the following proteins will be activated in order to suppress cell division if the cell is not ready or should not divide? Select one: a. p53 b. cdk c. cyclin d. seperase e. mitogenarrow_forward
- Cyclin D/cdk 4,6 inhibits retinoblastoma protein (Rb) binding to...., which ultimately affects gene expression. cycling-dependent kinase tramscription factor E2F p53 oncogenesarrow_forwardWhich of the following is an inhibitor of apoptosis? Question 3 options: a) Caspase b) cytochrome c c) Bcl-2 family d) p53arrow_forwardIn tumor cells Rb protein is hyperphosphorylated. In response to that, will p53 level increase or decrease? Why or why not? new answer pleasearrow_forward
- Radiation, which induces DNA damage, inhibits cancer progression by: Breaking down Rb Breaking down cohesin Activating p53 Phosphorylating Cdk Breaking down the mitotic spindlearrow_forwardA normally functioning gene that regulates the cell cycle by stopping cell division is most likely to be a(n) __________. Group of answer choices carcino-gene tumor suppressor proto-oncogene muta-gene oncogenearrow_forwardA mutated gene that codes for an altered version of Cdk that is active in the absence of cyclin is a(n) _____. a. kinase inhibitor. b. tumor suppressor gene. c. proto-oncogene. d. oncogene.arrow_forward
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