Human Heredity: Principles and Issues (MindTap Course List)
Human Heredity: Principles and Issues (MindTap Course List)
11th Edition
ISBN: 9781305251052
Author: Michael Cummings
Publisher: Cengage Learning
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Chapter 10.7, Problem 1EG
Summary Introduction

To explain: The way in which a single amino acid in beta globin chain can lead to  sickle cell anemia.

Introduction: Sickle cell anemia is a genetic disease that is inherited from one generation to next in an autosomal recessive manner. People suffering from this disease show mutations in the genes that code for the β-globin chain of hemoglobin. This results in the formation of improperly folded hemoglobin molecule. Red blood cells of people suffering from this disease are sickle shaped..

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The T-state of hemoglobin is favored over the R-state in blood under which of the listed conditions?
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