BuyFindarrow_forward

Human Heredity: Principles and Iss...

11th Edition
Michael Cummings
Publisher: Cengage Learning
ISBN: 9781305251052

Solutions

Chapter
Section
BuyFindarrow_forward

Human Heredity: Principles and Iss...

11th Edition
Michael Cummings
Publisher: Cengage Learning
ISBN: 9781305251052
Chapter 10.7, Problem 1EG
Textbook Problem
8 views

How might a single amino acid change in beta globin alter the molecule and cause sickle cell anemia?

Summary Introduction

To explain: The way in which a single amino acid in beta globin chain can lead to  sickle cell anemia.

Introduction: Sickle cell anemia is a genetic disease that is inherited from one generation to next in an autosomal recessive manner. People suffering from this disease show mutations in the genes that code for the β-globin chain of hemoglobin. This results in the formation of improperly folded hemoglobin molecule. Red blood cells of people suffering from this disease are sickle shaped..

Explanation of Solution

Sickle cell anemia is a disease caused due to genetic mutations in the genes that code for the β-globin chain of hemoglobin. In this mutation, adenine is replaced by thymine at sixth position of the gene that codes for β-globin chain of hemoglobin. This mutation results in formation of valine at the same codon position instead of glutamic acid in polypeptide sequence of β-globin chain...

Still sussing out bartleby?

Check out a sample textbook solution.

See a sample solution

The Solution to Your Study Problems

Bartleby provides explanations to thousands of textbook problems written by our experts, many with advanced degrees!

Get Started

Chapter 10 Solutions

Human Heredity: Principles and Issues (MindTap Course List)
Show all chapter solutions
add

Additional Science Textbook Solutions

Find more solutions based on key concepts
Show solutions add
Chloroplasts of green algae evolved from ______. a. cyanobacteria b. archaea c. red algae

Biology: The Unity and Diversity of Life (MindTap Course List)

Before athletic competitions, a moderate caffeine intake may interfere with concentration. may enhance performa...

Nutrition: Concepts and Controversies - Standalone book (MindTap Course List)

What behaviors would be most helpful in preventing osteoporosis?

Understanding Nutrition (MindTap Course List)

What is the usefulness of being camouflaged in natural environments?

Biology: The Dynamic Science (MindTap Course List)

As some molten metal splashes, one droplet flies off to the east with initial velocity vi at angle i above the ...

Physics for Scientists and Engineers, Technology Update (No access codes included)